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  • Adam D. Sylvester Lab

    Research in the Adam D. Sylvester Lab primarily focuses on the way in which humans and primates... move through the environment, with the aim of reconstructing the locomotor repertoire of extinct hominins and other primates. We use a quantitative approach that involves the statistical analysis of three-dimensional biological shapes, specifically musculoskeletal structures, and then link the anatomy to function and function to locomotor behavior. view more

    Research Areas: anatomy, biomechanics, locomotion, evolution, skeletal morphology
  • Adam Sapirstein Lab

    Lab Website

    Researchers in the Adam Sapirstein Lab focus on the roles played by phospholipases A2 and their... lipid metabolites in brain injury. Using in vivo and in vitro models of stroke and excitotoxicity, the team is examining the roles of the cytosolic, Group V, and Group X PLA2s as well as the function of PLA2s in cerebrovascular regulation. Investigators have discovered that cPLA2 is necessary for the early electrophysiologic changes that happen in hippocampal CA1 neurons after exposure to N-methyl-d-aspartate (NMDA). This finding has critical ramifications in terms of the possible uses of selective cPLA2 inhibitors after acute neurologic injuries. view more

    Research Areas: phospholipases A2, brain, stroke, lipid metabolites, excitotoxicity, brain injury, neurological disorders
  • Adamo Cardiac Immunology Lab

    Lab Website
    Principal Investigator:
    Luigi Adamo, M.D., Ph.D.
    Medicine

    Over the last few decades, a growing body of evidence has shown that the immune system is intim...ately connected with cardiac development, function and adaptation to injury. However, there is still much to learn and currently there are no immunomodulatory treatments to prevent or treat heart dysfunction.

    The Adamo Lab aims to study applied immunology in the context of cardiac function and dysfunction, to both elucidate fundamental properties of the immune systems and to develop novel therapeutic options for the rapidly growing number of patients living with heart disease.
    view more

    Research Areas: heart disease, immunology, cardiac function and dysfunction
  • Adrian Dobs Lab

    Principal Investigator:
    Adrian Dobs, M.D., M.H.S.
    Medicine

    Researchers in the Adrian Dobs Lab study topics that include gonadal dysfunction, hyperlipidemi...a, diabetes mellitus, and the relationship between sex hormones and heart disease. We currently are investigating male gonadal function—with particular interest in new forms of male hormone replacement therapy—and hormonal changes related to aging. view more

    Research Areas: diabetes mellitus, hormones, hyperlipidemia, male gonadal function, cardiovascular diseases, endocrinology
  • Adult Cardiac Catheterization Laboratory

    Principal Investigator:
    Jon Resar, M.D.
    Medicine

    Our group is interested in the evaluation of basic pathophysiology in patients undergoing cardi...ac procedures, development and evaluation of new therapeutic strategies, and improving patient selection and outcomes following interventional procedures. view more

    Research Areas: cardiac catheterization, Acute Myocardial Infarction
  • Advanced Optics Lab

    Lab Website
    Principal Investigator:
    Scot Kuo, Ph.D.
    Biomedical Engineering

    The Advanced Optics Lab uses innovative optical tools, including laser-based nanotechnologies, ...to understand cell motility and the regulation of cell shape. We pioneered laser-based nanotechnologies, including optical tweezers, nanotracking, and laser-tracking microrheology. Applications range from physics, pharmaceutical delivery by phagocytosis (cell and tissue engineering), bacterial pathogens important in human disease and cell division.

    Other projects in the lab are related to microscopy, specifically combining fluorescence and electron microscopy to view images of the subcellular structure around proteins.
    view more

    Research Areas: optics, microscopy, physics, cellular biology, imaging, nanotechnology, drugs, tissue engineering
  • Agrawal Lab

    Lab Website

    The Agrawal Lab is focused on the medical and surgical treatment of otologic and neurotologic c...onditions. Research is focused on the vestibular system (the inner ear balance system), and how the function of the vestibular system changes with aging. Particular focus is given to study how age-related changes in vestibular function influence mobility disability and fall risk in older individuals. view more

    Research Areas: cognition, visuospatial ability, vertigo, aging, balance, vestibular system
  • Ahmet Gurakar Lab

    Principal Investigator:
    Ahmet Gurakar, M.D.
    Medicine

    The Ahmet Gurakar Lab is interested in bioartificial liver dialysis systems and the application... of total plasma exchange in the treatment of liver disorders. view more

    Research Areas: transplants, viral hepatitis, liver diseases, plasma exchange
  • Alan Baer Lab

    Principal Investigator:
    Alan Baer, M.D.
    Medicine

    Research in the Alan Baer Lab focuses on Sjogren's syndrome. Previously, we conducted the Sjogr...en's International Registry (SICCA), enrolling 300 patients and creating a valuable source of clinical data and biospecimens for research we're conducting with colleagues at Johns Hopkins and the University of California-San Francisco. Currently, we're conducting a longitudinal observational study of patients with Sjogren's syndrome. We're also collaborating with Dr. Ben Larman in the Department of Pathology, using phage immuno-precipation sequencing to work on a characterization of the complete autoantibody repertoire in Sjogren's syndrome patients. view more

    Research Areas: autoantibodies, Sjogren's syndrome, autoimmune rheumatic diseases, observational data
  • Alan Scott Lab

    Principal Investigator:
    Alan Scott, Ph.D.
    Medicine

    Research in the Alan Scott Lab involves several important areas of genomics. Our team collabora...tes on a study to investigate the exon and genome sequence variants that determine phenotype, with a specific focus on the genetic bases of cleft lip and palate. We are also involved in assessing and improving genomic technologies to provide next-generation sequencing and analysis of sequence data to the clinical environment. In addition, we have a longstanding interest in the problem of gene annotation and the evolutionary genomics of vertebrates, especially endangered species. view more

    Research Areas: evolutionary genomics, sequence analysis, genomics, genome annotation, genomic technologies, cleft lip and palate
  • Albert Lau Lab

    Lab Website
    Principal Investigator:
    Albert Lau, Ph.D.
    Biophysics and Biophysical Chemistry

    The Lau Lab uses a combination of computational and experimental approaches to study the atomic... and molecular details governing the function of protein complexes involved in intercellular communication. We study ionotropic glutamate receptors (iGluRs), which are ligand-gated ion channels that mediate the majority of excitatory synaptic transmission in the central nervous system. iGluRs are important in synaptic plasticity, which underlies learning and memory. Receptor dysfunction has been implicated in a number of neurological disorders. view more

    Research Areas: central nervous system, synaptic plasticity, computational biology, intracellular communication, ionotropic glutamate receptors, neurological disorders
  • Alex Kolodkin Laboratory

    Lab Website
    Principal Investigator:
    Alex Kolodkin, Ph.D.
    Neuroscience

    Research in the Alex Kolodkin Laboratory is focused on understanding how neuronal connectivity ...is established during development. Our work investigates the function of extrinsic guidance cues and their receptors on axonal guidance, dendritic morphology and synapse formation and function. We have investigated how neural circuits are formed and maintained through the action of guidance cues that include semaphorin proteins, their classical plexin and neuropilin receptors, and also novel receptors. We employ a cross-phylogenetic approach, using both invertebrate and vertebrate model systems, to understand how guidance cues regulate neuronal pathfinding, morphology and synaptogenesis. We also seek to understand how these signals are transduced to cytosolic effectors. Though broad in scope, our interrogation of the roles played by semaphorin guidance cues provides insight into the regulation of neural circuit assembly and function. Our current work includes a relatively new interest in understanding the origins of laminar organization in the central nervous system. view more

    Research Areas: central nervous system, neural circuits, neurodevelopment, neuronal connectivity, laminar organization
  • Aliaksei Pustavoitau Lab

    The Aliaksei Pustavoitau Lab conducts research on models and mechanisms of impaired consciousne...ss in patients who have suffered acute brain injury. Examples of our work include a study on the mechanisms of neurologic failure in critical illness and another on the use of intensivist-driven ultrasound at the PICU bedside. We also have a longstanding interest in patient safety and quality of care in the ICU setting. view more

    Research Areas: patient safety, brain, consciousness, ICU, brain injury
  • Alicia Arbaje Lab

    Research in the Alicia Arbaje Lab aims to help older adults maintain dignity and quality of lif...e as they age. We are particularly interested in creating health care systems to improve safety and outcomes for older adults. view more

    Research Areas: safety, gerontology, health care systems
  • Aline Charabaty Lab

    Principal Investigator:
    Aline Charabaty Pishvaian, M.D.
    Medicine

    The Aline Charabaty Lab performs clinical research on Inflammatory Bowel Disorder.

    Research Areas: Inflammatory Bowel Disorder
  • Alison E. Turnbull Lab

    Lab Website

    Research in the Alison E. Turnbull Lab focuses on patient-clinician interactions. We study deci...sion-making processes for ICU patients and their families and focus on the long-term outcomes of ICU survivors. Additional research examines ways to improve end-of-life care for patients. view more

    Research Areas: epidemiology, palliative care, medical decision making, ICU
  • Alison Miles Lab

    Research in the Alison Miles Lab focuses on moral distress among pediatric intensive care unit ...(PICU) clinicians. We have interviewed practitioners involved in the long-term care of patients in the PICU from two months to two years. By identifying the challenges of these cases and what was learned, we hope to develop more effective stress-management strategies for providers. Providers who have less stress are better equipped to care for patients, including those living with chronic diseases. Our team hopes to ultimately improve the field of pediatric palliative care for patients, families and care providers. view more

    Research Areas: stress, intensive care
  • Alison Moliterno Lab

    Principal Investigator:
    Alison Moliterno, M.D.
    Medicine

    The Alison Moliterno Lab studies the molecular pathogenesis of myeloproliferative disorders (MP...Ds), including polycythemia vera, essential thrombocytosis and idiopathic myelofibrosis. Our research is focused on the genetic and epigenetic lesions associated with MPDs, with the goal of improving diagnosis and treatment for these disorders. view more

    Research Areas: blood disorders, idiopathic myelofibrosis, essential thrombocytosis, epigenetics, genomics, polycythemia vera, myeloproliferative disorders
  • Allan Gelber Lab

    The Allan Gelber Lab conducts research on the clinical epidemiology of rheumatic disorders. Our... recent studies have explored topics that include the predicting factors of prevalent and incident gout; cardiovascular disease burden and risk in patients with rheumatoid arthritis; autoantibodies in both primary and secondary SjogrenÕs syndrome; and predictors of outcomes in patients with scleroderma. In addition, we have a long-standing interest in the ways in which racial differences affect disease manifestations in relation to rheumatic disorders. view more

    Research Areas: rheumatology, gout, Sjogren's syndrome, scleroderma, race, health disparities, rheumatoid arthritis
  • Allan Gottschalk Lab

    Research in the Allan Gottschalk Lab focuses on the mechanisms behind neuropathic pain, chronic... pain related to nerve injury. We are investigating biophysical models of the impact of general anesthesia on the central nervous system; informational aspects of sensory perception and the representation of sensory input; nonlinear dynamics of respiratory pattern generation; and acute perioperative pain. view more

    Research Areas: sensory perception, nerve injury, central nervous system, neuropathy, neuropathic pain, anesthesia, pain
  • ALS Center

    Lab Website
    Principal Investigator:
    Nicholas Maragakis, M.D.
    Neurology

    The ALS Center for Cell Therapy and Regeneration Research at Johns Hopkins is committed to iden...tifying the causes of the neurodegenerative disease, amyotrophic lateral sclerosis (ALS), and discovering new and effective treatment options. At the ALS Center, Johns Hopkins researchers work with other investigators, including those at the Robert Packard Center for ALS Research at Johns Hopkins and clinicians within the Johns Hopkins ALS Clinic to aggressively take groundbreaking scientific discoveries and turn them into clinical applications that will improve the quality of life of those diagnosed with ALS. view more

    Research Areas: ALS
  • Alyssa Parian Lab

    Principal Investigator:
    Alyssa Parian, M.D.
    Medicine

    The Alyssa Parian Lab works to identify early markers of dysplasia. We also study inflammatory ...bowel disease-associated cancers, conduct IBD clinical trials and examine IBD extraintestinal manifestations. view more

    Research Areas: inflammatory bowel disease, cancer, displaysia
  • Alzheimer's Disease Research Center

    Lab Website
    Principal Investigator:
    Marilyn Albert, Ph.D.
    Neurology

    The goal of the Johns Hopkins Alzheimer's Disease Research Center (ADRC) is to accelerate the d...iscovery of new treatments that are directed at the basic mechanisms of disease, and to hasten the time when effective treatments for AD and related disorders become a reality. We have a strong commitment to basic research regarding the underlying mechanisms of Alzheimer's Disease and related disorders, and how this may translate into effective treatment. We perform clinical research seeking to identify medications to delay or treat the symptoms of dementia. We also provided many educational programs for family members and professionals. view more

    Research Areas: dementia, Alzheimer's disease
  • Ami Shah Lab

    Lab Website
    Principal Investigator:
    Ami Shah, M.D.
    Medicine

    Researchers in the Ami Shah Lab study scleroderma and Raynaud’s phenomenon. We examine the rela...tionship between cancer and scleroderma, with a focus on how and if cancer causes scleroderma to develop in some patients. We are currently conducting clinical research to study ways to detect cardiopulmonary complications in patients with scleroderma, biological and imaging markers of Raynaud’s phenomenon, and drugs that improve aspects of scleroderma. view more

    Research Areas: Raynaud's phenomenon, cancer, scleroderma, drugs, cardiovascular diseases
  • Amit Pahwa Lab

    Principal Investigator:
    Amit Pahwa, M.D.
    Medicine

    The Amit Pahwa Lab conducts research on a variety of topics within internal medicine. Our most ...recent studies have explored misanalysis of urinalysis results, urinary fractional excretion indices in the evaluation of acute kidney injury and nocturnal enuresis as a risk factor for falls in older women. We also investigate cancer diagnostics and treatments. In this area, our recent research has included studying cutaneous shave biopsies for diagnosing primary colonic adenocarcinoma as well as growth inhibition and apoptosis in human brain tumor cell lines using selenium. view more

    Research Areas: acute kidney injury, cancer, internal medicine, urology
  • Amita Gupta Lab

    Principal Investigator:
    Amita Gupta, M.D., M.H.S.
    Medicine

    The Amita Gupta Lab focuses on drug trials to prevent and treat HIV, tuberculosis (TB) and othe...r co-morbidities in adults, including pregnant women and children who reside in low-income settings. We also conduct cohort studies assessing HIV, inflammation and nutrition in international settings; TB in pregnancy; and risk factors for TB in India (CTRIUMPH). We collaborate with several faculty in the Center for TB Research, Division of Infectious Diseases and the School of Public Health. view more

    Research Areas: global health, nutrition, infectious disease, HIV, inflammation, tuberculosis
  • Amy Kim Lab

    Principal Investigator:
    Amy K. Kim, M.D.
    Medicine

    The Amy Kim Lab performs basic, translational, and clinical research on liver lesions and hepat...ocellular carcinoma. view more

    Research Areas: Liver lesions, hepatocellular carcinoma
  • Amy Knight Lab

    Principal Investigator:
    Amy Knight, M.D.
    Medicine

    Research in the Amy Knight Lab focuses on methods by which information technology can improve t...he quality of health care. We investigate the role computer systems can play in expanding patient-doctor communication, streamlining healthcare tasks for both medical students and practitioners, and establishing a higher standard of care. Our studies have explored the effectiveness of semi-automating daily progress notes for improved documentation, peer assessment of professional performance among hospitalists, ways to enable patient-centered care using information technology and other topics. view more

    Research Areas: outcomes, patient-provider relationships, internal medicine, information technology
  • Ana-Marie Orbai Lab

    Lab Website
    Principal Investigator:
    Ana-Maria Orbai, M.D., M.H.S.
    Medicine

    The Ana-Marie Orbai Lab focuses on inflammatory arthritis. Current clinical research projects i...n the lab examine patient symptoms and experiences in rheumatic diseases and inflammatory arthritis. We focus on stiffness in rheumatoid arthritis and patient-reported outcomes. Previous research in the lab focused on systemic lupus erythemaous (SLE). view more

    Research Areas: autoimmune rheumatic diseases, arthritis, rheumatoid arthritis
  • Andrea Cox Lab

    Principal Investigator:
    Andrea Cox, M.D., Ph.D.
    Medicine

    Research in the Andrea Cox Lab explores the immune response in chronic viral infections, with a... focus on HIV and the hepatitis C virus (HCV). In our studies, we examine the role of the immune response upon exposure to HCV by examining responses to HCV in a longitudinal, prospective group of high-risk individuals. This enables us to compare the innate, humoral and cellular immune responses to infection with clearance versus persistence. Through our findings, we seek to identify mechanisms of protective immunity against HCV infection and improve HCV vaccine design. view more

    Research Areas: virology, vaccines, viral immunology, HIV, hepatitis C, T cells
  • Andrew Feinberg Laboratory

    Lab Website
    Principal Investigator:
    Andrew Feinberg, M.D., M.P.H.
    Medicine

    The Feinberg Laboratory studies the epigenetic basis of normal development and disease, includi...ng cancer, aging and neuropsychiatric illness. Early work from our group involved the discovery of altered DNA methylation in cancer as well as common epigenetic (methylation and imprinting) variants in the population that may be responsible for a significant population-attributable risk of cancer.

    Over the last few years, we have pioneered the field of epigenomics (i.e., epigenetics at a genome-scale level), founding the first NIH-supported NIH epigenome center in the country and developing many novel tools for molecular and statistical analysis. Current research examines the mechanisms of epigenetic modification, the epigenetic basis of cancer, the invention of new molecular, statistical, and epidemiological tools for genome-scale epigenetics and the epigenetic basis of neuropsychiatric disease, including schizophrenia and autism.
    view more

    Research Areas: autism, cancer, epigenetics, schizophrenia, human development, aging, DNA, genomics, neuropsychiatric disease
  • Andrew Laboratory: Center for Cell Dynamics

    Lab Website
    Principal Investigator:
    Deborah Andrew, Ph.D., M.S.
    Cell Biology

    Researchers in the Center for Cell Dynamics study spatially and temporally regulated molecular ...events in living cells, tissues and organisms. The team develops and applies innovative biosensors and imaging techniques to monitor dozens of critical signaling pathways in real time. The new tools help them investigate the fundamental cellular behaviors that underlie embryonic development, wound healing, cancer progression, and functions of the immune and nervous systems. view more

    Research Areas: immunology, cancer, epithelial tube, nervous system, molecular biology
  • Andrew Lane Lab

    The Lane laboratory is focused on understanding molecular mechanisms underlying chronic rhinosi...nusitis, particularly the pathogenesis of nasal polyps, as well as inflammation on the olfactory epithelium. Diverse techniques in molecular biology, immunology, and physiology are utilized to study epithelial cell innate immunity, olfactory loss, and response to viral infection. Ongoing work explores how epithelial cells of the sinuses and olfactory mucosa participate in the immune response and contribute to chronic inflammation. The lab creates and employs transgenic mouse models of chronic nasal/sinus inflammation to support research in this area. Collaborations are in place with the School of Public Health to explore mechanisms of anti-viral immunity in influenza and COVID-19. view more

    Research Areas: nasal polyps, immunology, COVID-19, olfaction, cell culture, transgenic mice, chronic rhinosinusitis, innate immunity, neuroscience, molecular biology
  • Andrew McCallion Laboratory

    Principal Investigator:
    Andy McCallion, Ph.D.
    Molecular and Comparative Pathobiology

    The McCallion Laboratory studies the roles played by cis-regulatory elements (REs) in controlli...ng the timing, location and levels of gene activation (transcription). Their immediate goal is to identify transcription factor binding sites (TFBS) combinations that can predict REs with cell-specific biological control--a first step in developing true regulatory lexicons.

    As a functional genetic laboratory, we develop and implement assays to rapidly determine the biological relevance of sequence elements within the human genome and the pathological relevance of variation therein. In recent years, we have developed a highly efficient reporter transgene system in zebrafish that can accurately evaluate the regulatory control of mammalian sequences, enabling characterization of reporter expression during development at a fraction of the cost of similar analyses in mice. We employ a range of strategies in model systems (zebrafish and mice), as well as analyses in the human population, to illuminate the genetic basis of disease processes. Our long-term objective is to use these approaches in contributing to improved diagnostic, prognostic and therapeutic strategies in patient care.
    view more

    Research Areas: cell biology, genomics, gene regulation, nervous system
  • Aniket Sidhaye Lab

    Lab Website
    Principal Investigator:
    Aniket Sidhaye, M.D.
    Medicine

    Dr. Sidhaye is interested in improving the care of persons with cystic fibrosis, type 1 diabete...s mellitus and hospitalized person with diabetes. research topics include bone health of persons with CF undergoing lung transplant, CF-related diabetes mellitus, Care of persons with type 1 diabetes mellitus transitioning from pediatrics to adult specialty clinics, Management of hospitalized persons with diabetes. view more

    Research Areas: biochemistry, obesity, hormones, diabetes, transitional care, endocrinology, thyroid
  • Anne Marie Lennon Lab

    The Lennon Lab does clinical and translational research on endoscopic ultrasound, esophageal ca...ncer, gastric cancer, gastroenterology, pancreatic cancer, pancreatic cysts, therapeutic endoscopy, Von Hippel-Lindau (VHL)

    view more

    Research Areas: Von Hippel-Lindau (VHL), gastroenterology, pancreatic cancer, Endoscopic Ultrasound, Esophageal Cancer, Pancreatic Cysts, Therapeutic Endoscopy, Gastric Cancer
  • Anne Rompalo Lab

    Principal Investigator:
    Anne Rompalo, M.D.
    Medicine

    Research in the Anne Rompalo Lab focuses on STD research and application. We recently examined ...the relationship between violence against women and HIV-related risk factors in women living in the United States. Past projects include a nine-year longitudinal observation study of HIV-infected women in Baltimore. view more

    Research Areas: women, HIV, sexually transmitted diseases, domestic violence
  • Antoine Azar Lab

    Principal Investigator:
    Antoine Azar, M.D.
    Medicine

    The Antoine Azar Lab conducts research on topics related to primary immunodeficiency diseases, ...allergies and lung disease. Specifically, we explore the role of primary immunodeficiency in certain difficult-to-treat chronic lung diseases, such as COPD, emphysema and asthma. view more

    Research Areas: emphysema, immunology, asthma, allergies, lung disease, COPD
  • Antony Rosen Lab

    Principal Investigator:
    Antony Rosen, M.B.Ch.B., M.S.
    Medicine

    Research in the Antony Rosen Lab investigates the mechanisms shared by the autoimmune rheumatic... diseases such as lupus, myositis, rheumatoid arthritis, scleroderma and SjogrenÕs syndrome. We focus on the fate of autoantigens in target cells during various circumstances, such as viral infection, relevant immune effector pathways and exposure to ultraviolet radiation. Our recent research has sought to define the traits of autoantibodies that enable them to induce cellular or molecular dysfunction. We also work to better understand the mechanisms that form the striking connections between autoimmunity and cancer. view more

    Research Areas: myositis, lupus, rheumatology, Sjogren's syndrome, scleroderma, autoimmune rheumatic diseases, rheumatoid arthritis
  • Ari Cedars Laboratory

    Principal Investigator:
    Ari Cedars, M.D.
    Medicine

    Ari Cedars, M.D., and his team have three primary research goals. First, the Cedars Lab is inte...rested in patient-centered outcomes in congenital heart disease, which they investigate using a digital tracking system to record participants’ symptoms and quality of life. Second, the Cedars Lab investigates outcomes with mechanical circulatory support and transplant in congenital heart disease, with a focus on those with end-stage heart disease and a Fontan circulation. Third, the Cedars Lab is interested in the biological mechanisms underlying circulatory deterioration and end-organ dysfunction in patients with a Fontan circulation. view more

    Research Areas: heart disease, congenital heart disease
  • Ariel Green Lab

    Research in the Ariel Green Lab focuses on informing and improving decisions surrounding the us...e of invasive medical technologies for older adults with complex medical diseases. Our long-term goals are to conduct epidemiologic research, create public health initiatives, and help shape policies that improve the lives of older adults. view more

    Research Areas: epidemiology, health care policy, decision making, gerontology
  • Arturo Casadevall Lab

    The Arturo Casadevall Lab uses a multidisciplinary approach to explore two key topics within mi...crobiology and immunology: how microbes cause disease and how hosts can protect themselves against those microbes. Much of our research focuses on the fungus Cryptococcus neoformans, which frequently causes lung infections in people with impaired immunity. We also work with the microorganism Bacillus anthracis, a bacterium that causes anthrax and is frequently used in biological warfare. Our goal is to devise antibody-based countermeasures to protect against this and other similar threats. view more

    Research Areas: microbiology, immunology, vaccines, cryptococcus neoformans, tuberculosis
  • Ashish Nimgoankar Lab

    The Ashish Nimgoankar Lab is interested in translational technology development and image-guide...d therapies. view more

    Research Areas: translational technology, imaging
  • Athir Morad Lab

    Lab Website

    Research in the Athir Morad Lab primarily focuses on perioperative pain management for neurosur...gery patients. Our team has conducted two randomized controlled trials to assess the efficacy of patient-controlled analgesia (PCA) following craniotomy. Our current research includes studies on the safety of opioid administration following craniotomy through the use of end-tidal CO2 detection, as well as research into the use of transcortical magnetic stimulation (TMS) for managing pain after spine surgery. view more

    Research Areas: neurosurgery, opioids, spine, anesthesiology, pain
  • Auditory Brainstem Laboratory

    Lab Website

    The overall goal of the Auditory Brainstem Library is to understand how abnormal auditory input... from the ear affects the brainstem, and how the brain in turn affects activity in the ear through efferent feedback loops. Our emphasis is on understanding the effects of different forms of acquired hearing loss (genetic, conductive, noise-induced, age-related, traumatic brain injury-related) and environmental noise. We are particularly interested in plastic changes in the brain that compensate for some aspects of altered auditory input, and how those changes relate to central auditory processing deficits, tinnitus, and hyperacusis. Understanding these changes will help refine therapeutic strategies and identify new targets for treatment. We collaborate with other labs in the Depts. of Otolaryngology, Neuroscience, Neuropathology, the Wilmer Eye Institute, and the Applied Physics Laboratory at Johns Hopkins, in addition to labs outside the university to increase the impact and clinical relevance of our research. view more

    Research Areas: hearing disorders, compound action potentials, auditory brainstem response, otoacoustic emissions, operation conditions, audiology, acoustic startle modification, hearing, neurology
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