Roland Griffiths Laboratory

  • The Roland Griffiths Laboratory is studying the behavioral pharmacology of drugs of abuse. One research program focuses on the behavioral pharmacology of benzodiazepines and related compounds. Human studies involve assessment of subjective effects, behavioral changes, tolerance and drug self-administration. Another research program is examining the reinforcing, discriminative, tolerance-producing and physical dependence-producing effects of caffeine in humans and baboons. We are also studying several other classes of abused drugs: opioids, anorectic stimulants, phencyclidine derivatives and hallucinogens. These studies provide information about the behavioral pharmacology and abuse liability of these drugs.

    Research Areas: opioids, hallucinogens, caffeine, benzodiazepines, drugs, pharmacology, phencyclidine derivatives, anorectic stimulants