Irritable Bowel Disease Genetic Research Laboratory

  • Research in the Irritable Bowel Disease Genetic Research Laboratory focuses on the genetic variation in etiopathogenesis, disease manifestations and disease course in inflammatory bowel disease (IBD), Crohn’s disease and ulcerative colitis. We focus on familial IBD as well as IBD in the African-American and Ashkenazi Jewish populations. Our lab uses gene and genome-wide association mapping studies and whole genome sequencing to identify and characterize susceptibility genes for IBD in those populations. Additional studies examine how infectious diseases can possibly trigger Crohn’s disease and investigate the role of vitamin D and genetic modifiers of vitamin D in causing Crohn’s disease.

    Research Areas: inflammatory bowel disease, Crohn’s disease, colitis, vitamin D, genomics

    Lab Website

    Principal Investigator

    Steven Brant, M.D.