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George Rose Lab

George Rose, Ph.D.

Principal Investigator:
George Rose, Ph.D.
Department:
Anesthesiology and Critical Care Medicine

The George Rose Lab investigates protein folding, the spontaneous disorder transition that takes place under physiological conditions. The protein polymer is flexible in its unfolded state but takes on a unique native, three-dimensional form when folded. We propose that the folded state is selected from a set number of structural possibilities, each corresponding to either a distinct hydrogen-bonded arrangement of ??helices or a strand of ??sheet.

Research Areas: biophysics, biochemistry, protein folding, protein structure

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