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Precision Immunotherapy

Precision Immunotherapy

Developed from 30 years of basic research at Johns Hopkins and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, an immunotherapy drug has now been FDA approved for cancer based on disease genetics rather than type. Bert Vogelstein and Dung Le describe this research milestone.  
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 The Science Behind Memory Formation

The Science Behind Memory Formation

Richard Huganir explains how studies on the molecular basis of memory formation can help researchers find new therapies for Alzheimer’s, age-related dementia, post-traumatic stress disorder, schizophrenia and autism.  Learn More
Organizing the Nuclear Closet

Organizing the Nuclear Closet

Have you ever wondered how the nucleus can contain and protect all the cell’s chromosomes while still allowing genes to do their work? Kathy Wilson explains why the nucleus is the world’s most organized closet.

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Eliminating Eye Drops

Eliminating Eye Drops

When it comes to applying medication into our eyes, the struggle is real – we miss the target and sometimes even scratch our eyes.  Peter McDonnell’s team aims to solve this problem by developing a better delivery method. Learn More
Blocking Rogue Genes

Blocking Rogue Genes

Philip Cole discusses how his research group is synthesizing new molecules that can block the action of disease-causing genes. Their research can help in developing new cancer treatments.

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Ubiquitin Signals

Ubiquitin Signals

Cynthia Wolberger’s team studies how a protein called ubiquitin switches genes on and off or notifies the cell about DNA damage.  Studying this protein might help scientists to develop new drugs for certain types of cancer that currently have no effective treatment.

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The Importance of Platelets

The Importance of Platelets

Kelly Metcalf Pate studies how platelets in the blood team together to stop bleeding and fight infection. Her team is studying whether a low platelet number impairs the body’s ability to defend itself from HIV.

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Regenerative Medicine

Regenerative Medicine

Every cell in our body contains the instructions necessary to generate all of our tissues and organs. Here, Luis Garza explains how regenerative medicine can leverage this information to rebuild organs in adults.

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 Using Stem Cells to Treat Blood Disorders

Using Stem Cells to Treat Blood Disorders

Elias Zambidis cares for children suffering from leukemia and other blood disorders. His laboratory studies human stem cells, which may one day be used to treat not only blood disorders, but also heart disease, vascular disease, cancer and autoimmune diseases.

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