Print This Page

Sign Up for Fundamentals

Stay up-to-date with the latest research findings from the Institute for Basic Biomedical Sciences.

Fundamentals Topics+

Profiles

Profiles

Dan O’Connor on the Importance of Touch

Dan O’Connor on the Importance of Touch

Neuroscientist Dan O’Connor’s research focuses on understanding what happens in our brain to perceive touch – a sense plays a crucial role in how we interpret our surroundings, move around and even our perception of pain. His lab has recently made a new discovery on how our brains process touch.

Learn More
David Zappulla on the Role of Telomeres in Aging

David Zappulla on the Role of Telomeres in Aging

David Zappulla is a research associate in the of Molecular Biology & Genetics. His lab studies the molecular mechanisms of telomerase function in yeast in the hopes of helping to pave the way for better understanding of telomere biology in humans, and to identify interventions to improve human health.
Learn More
 Natalia Trayanova on Virtual Hearts that Save Lives

Natalia Trayanova on Virtual Hearts that Save Lives

Natalia Trayanova is a professor of biomedical engineering and medicine. Her lab creates predictive computer simulations to generate personalized virtual hearts to assess patient risk of sudden cardiac death and to guide personalized anti-arrhythmia interventions 
Learn More
Xingde Li on Non Invasive Probes to Visualize Living Cells

Xingde Li on Non Invasive Probes to Visualize Living Cells

Xingde Li is a professor of biomedical engineering at the Johns Hopkins University School of Medicine. His lab focuses on novel endomicroscopy technologies in the hopes of someday diminishing our dependency on biopsies..

Learn More
Siobhán Cooke on Why Paleontologists Would Teach Anatomy

Siobhán Cooke on Why Paleontologists Would Teach Anatomy

Siobhán Cooke is an assistant professor of functional anatomy and evolution. Her research focuses on the evolution and eventual extinction of the native mammals of the Caribbean region. She also teaches human anatomy to medical students. 

Learn More
Seth Blackshaw on How the Brain Controls Sleep

Seth Blackshaw on How the Brain Controls Sleep

Seth Blackshaw is a professor of neuroscience, neurology and ophthalmology at the Johns Hopkins University School of Medicine. He recently published a paper describing newly identified brain cells in mice that play a major role in promoting sleep. 
Learn More
Haig Kazazian on ‘Jumping Genes’ and Their Relation to Genetic Disease

Haig Kazazian on ‘Jumping Genes’ and Their Relation to Genetic Disease

Haig Kazazian is a professor of pediatrics and molecular biology and genetics. His current research uses next generation DNA sequencing to investigate the role of LINE-1 (L1) genes in human diseases, such as cancer.

Learn More
Alan Scott on Next Generation Genome Sequencing

Alan Scott on Next Generation Genome Sequencing

Alan Scott, is an associate professor in the McKusick-Nathans Institute of Genetic Medicine. He recently led a team that developed a faster, less expensive method for whole genome sequencing which he plans to use to study genome evolution in rare and endangered species. 
Learn More
King-Wai Yau on Night Vision That’s Not “on the Brain”

King-Wai Yau on Night Vision That’s Not “on the Brain”

King-Wai Yau, professor of neuroscience and ophthalmology, investigates sight and smell. He is currently studying how nocturnalnon-primate animals make their pupils constrict without using their brain. 
Learn More
Alena Savonenko on Investigating the Role of Aging in the Development of Alzheimer’s Disease

Alena Savonenko on Investigating the Role of Aging in the Development of Alzheimer’s Disease

Alena Savonenko is an associate professor of pathology and neurology. She investigates the neurobiological mechanisms of aging, learning and memory. Her current research studies the mechanism of aging and why it is fundamental in the development of Alzheimer’s disease.
 
Learn More
Liz Tucker on Improving Outcomes for Children with Tuberculosis Meningitis.

Liz Tucker on Improving Outcomes for Children with Tuberculosis Meningitis.

Liz Tucker is an assistant professor of anesthesiology and critical care medicine and specializes in pediatric critical care in the PICU. Her most current research studies neuroinflammation caused by central nervous system TB, which occurs most commonly in children.
Learn More
Ben Larman on a New Method to Measure Gene Expression in Patient Tissues

Ben Larman on a New Method to Measure Gene Expression in Patient Tissues

Ben Larman is an assistant professor in the Department of Pathology, in the Division of Immunology. He spoke with Fundamentals about a new technique for analyzing the RNA content of human tissues.

Learn More
Dung Le on the Hard Work Behind a Historic Drug Approval

Dung Le on the Hard Work Behind a Historic Drug Approval

Dung Le is an associate professor of oncology at the Johns Hopkins University School of Medicine and member of the Johns Hopkins Bloomberg~Kimmel Institute. She co-led a clinical trial that was instrumental in the Food and Drug Administration’s recent approval of the drug pembrolizumab to treat cancers based on their genetic characteristics.
Learn More
Jody Tversky on a New Method to Analyze Skin Testing for Allergies

Jody Tversky on a New Method to Analyze Skin Testing for Allergies

Jody Tversky is an assistant professor and former Clinical Director of the Division of Allergy and Clinical Immunology. Here he discusses what scotch tape and drones have to do with allergy testing.

Learn More
Jiajia Zhang on her journey back to grad school.

Jiajia Zhang on her journey back to grad school.

Jiajia Zhang was a trained oncologist in China when she read news about former Vice President Joe Biden's visit to Johns Hopkins and the launch of the Bloomberg-Kimmel Institute for Cancer Immunotherapy. She decided to focus the rest of her career on research, and she was accepted into a master of public health program in the Johns Hopkins Bloomberg School of Public Health. 

Learn More
Kathleen Cullen on the Electric Appeal of the Brain

Kathleen Cullen on the Electric Appeal of the Brain

Kathleen Cullen is a professor of biomedical engineering. Here, she talks about the synergy of neuroscience and engineering, and how both come into play in an often-overlooked sixth sense.
Learn More
Kathleen Gabrielson on the toxic effects of stress

Kathleen Gabrielson on the toxic effects of stress

Kathleen Gabrielson is an associate professor in the Department of Molecular and Comparative Pathobiology. She investigates the side effects of medications, and the impact of stress on the body.

Learn More
Piotr Walczak on Visualizing Stem Cell Treatments

Piotr Walczak on Visualizing Stem Cell Treatments

Piotr Walczak is an associate professor of radiology and radiological science. He develops noninvasive imaging techniques to monitor stem cell therapies for neurological disorders, particularly those that affect the protective myelin sheath around nerves. 

Learn More
Albert Lau on the Mechanics of Biological Machines

Albert Lau on the Mechanics of Biological Machines

Albert Lau is an assistant professor of biophysics and biophysical chemistry. He studies the actions and interactions of molecules in atomic detail, focusing on signaling proteins in the brain.

Learn More
David Valle on the Johns Hopkins inHealth Initiative

David Valle on the Johns Hopkins inHealth Initiative

David Valle is director of the McKusick-Nathans Institute of Genetic Medicine. He works to discover the genetic causes of disease and is part of the Johns Hopkins inHealth steering committee.

Learn More
Carol Greider on the Importance of Sharing Results ‘ASAP’

Carol Greider on the Importance of Sharing Results ‘ASAP’

Carol Greider, a self-proclaimed rogue scientist and ASAPbio activist, talks about the initiative to change scientific publishing to better promote the free flow of ideas.

Learn More
Jordan Green on LEGOS and Nanoparticles

Jordan Green on LEGOS and Nanoparticles

Jordan Green is an associate professor of biomedical engineering. He designs sophisticated molecules with specialized tasks, such as delivering therapeutics to help the body heal.

Learn More
Kristina Nielsen on How the Brain Turns Pixels into Objects

Kristina Nielsen on How the Brain Turns Pixels into Objects

Kristina Nielsen is an assistant professor of neuroscience with the Zanvyl Krieger/Mind Brain Institute. She studies how nerve cells are organized in the brain’s visual areas to enable object recognition. 

Learn More
Sergi Regot on Seeing Cells as Individuals

Sergi Regot on Seeing Cells as Individuals

Sergi Regot is an assistant professor of molecular biology and genetics. He designs ways to study protein activity in real time, in living cells, one at a time.

Learn More