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Revising The Genome

Using CRISPR-Cas9, a revolutionary gene-editing technique, Geraldine Seydoux can delete, replace, or reprogram a nematode gene at will—and then step back and observe the result. 

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How Odor Sensitive Cells Regenerate

Odor-sensitive cells can warn of us of dangers and let us know when something is pleasant to eat. When exposed to the outside world, these cells can die but are quickly replaced. Randall Reed is trying to understand how regeneration happens in hopes to prevent people from losing their sense of smell.

Siobhan Cooke

Siobhán Cooke on Why Paleontologists Would Teach Anatomy

Siobhán Cooke is an assistant professor of functional anatomy and evolution. Her research focuses on the evolution and eventual extinction of the native mammals of the Caribbean region. She also teaches human anatomy to medical students. 

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‘Filter’ Hones Gwas Results to Help Researchers Avoid Dead Ends

Researchers develop a new strategy that gives scientists a biologically informed way to select genes to study and avoid “dead-end paths”. This can accelerate the study of study of diseases such as Parkinson’s, Alzheimer’s, schizophrenia and even addiction. Read more.

Image of the Month

An Instagram photo, by graduate student Kyla Britson, shows a battle between the body and its own muscle cells. Hopkins researchers: submit your images  here.
Itchy nose

An Itch You Can’t Scratch

Researchers have found that itch receptors previously discovered in skin are also present in the airways and that, when activated, these receptors appear to contribute to airway constriction and hypersensitivity, hallmarks of asthma and other respiratory disorders.  Read more.

How Short is Too Short?

Research shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure. Read more.

The Golgi Apparatus: The Cells’ Post Office and Now Stress Fighter

Researchers identified a biochemical pathway that allows the Golgi apparatus to combat stress caused by free radicals and oxidants. The findings could help in new ways to protect cells against the type of oxidative stress linked to Huntington’s disease. Learn more.