Print This Page

Sign Up for Fundamentals

Stay up-to-date with the latest research findings from the Institute for Basic Biomedical Sciences.

Fundamentals Topics+

Highlights

Highlights

Johns Hopkins Co-Organizes First International Meeting on Brain Health
Johns Hopkins Co-Organizes First International Meeting on Brain Health
About 300 people attended the meeting, held July 31 through Aug. 2, which also covered basic research and translational medicine, as well as the intersection of arts and the mind.
Learn more.
Genetic Clues Link Depression and Alcohol Dependence
Genetic Clues Link Depression and Alcohol Dependence
For more than a century, researchers have been trying to understand the association between depression and alcohol dependence. Research findings point to a shared genetic susceptibility that contributes to the co-occurrence of both conditions.
Read more.
Probing Deep Brain Stimulation for Alzheimer’s Disease
Probing Deep Brain Stimulation for Alzheimer’s Disease
Doctors Gwenn Smith and Constantine Lyketsos have been collaborating on a multicenter phase II study of deep brain stimulation in patients ages 45 to 85 with Alzheimer’s disease. The results are promising.
Learn more.
Engineering the Future of Medicine
Engineering the Future of Medicine
Michael Miller, director of the Johns Hopkins Department of Biomedical Engineering, details his plan for a new era of biomedical science discovery to respond to the challenges of the 21st century. 
 
Learn more.
Mitochondrial DNA Could Predict Risk for Sudden Cardiac Death, Heart Disease
Mitochondrial DNA Could Predict Risk for Sudden Cardiac Death, Heart Disease
Researchers report that the level of mitochondrial DNA is a novel and distinct biomarker able to predict the risk of heart attacks and sudden cardiac deaths a decade or more before they happen. 
 
Read more.
Fruit Fly Muscles Solve the mystery of Hypertrophic Cardiomyopathy
Fruit Fly Muscles Solve the mystery of Hypertrophic Cardiomyopathy

An inherited heart muscle disorder now mimicked in fruit flies helped researchers find the molecular flaw in hypertrophic cardiomyopathy. 

Learn more.
‘Bipolar’ Mice Help Researchers Understand the Biology of the Disorder
‘Bipolar’ Mice Help Researchers Understand the Biology of the Disorder

Genetically engineered mice displayed many of the behavioral hallmarks of human bipolar disorder. Behavior was reversed using well-established drug treatments. 

Read more.
Links Uncovered Between Genes and Body Tissues
 Links Uncovered Between Genes and Body Tissues

The results could help show how individual genetic differences contribute to disease and could guide treatments for heritable disorders such as Alzheimer’s disease, high cholesterol or Type 1 diabetes. 

Learn more.
3-D Printing Models of Human Organs
3-D Printing Models of Human Organs

A cardiac surgeon and a graduate student collaborated to solve a peculiar puzzle: Could they produce a three-dimensional model of a baby’s heart?

Read more.
Drunk Mice Experience Changes in Their Epigenome
 Drunk Mice Experience Changes in Their Epigenome

These changes may explain at least some of the differences in how cholesterol is processed in people who drink alcohol, or may affect those taking a new class of drugs designed to reduce LDL cholesterol. 

Learn more.