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Fundamentals

Fueling the Hummingbird’s Extreme Biology

To keep up the blistering pace of their flight, hummingbirds need to maintain their blood sugar levels high enough to cause serious disease in human. Yet, these birds show no sign of diabetes or obesity. Researchers from Johns Hopkins are studying hummingbird’s metabolism in hopes that their work could yield insights into what goes wrong in human diabetes and obesity.

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Loeys-Dietz Syndrome– Hal Dietz

Hal Dietz, director of the Smilow Center for Marfan Syndrom, discusses the progress and promise of treatment and research on Loeys-Dietz syndrome, with support from the Kasper family to keep research moving forward.

Caroline Vissers

Caroline Vissers on Diversity in Science and Science Communication

Caroline Vissers is a graduate student in Biochemistry, Molecular and Cellular Biology at Johns Hopkins Medicine University School of Medicine. Her essay “Diversity at the Top of the Social Media Signaling Cascade” won 3rd place in the Lasker Foundation Essay Contest.

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Highlights

fish retina

Image of the Month: Fish Eyes

The strange glow is caused by jellyfish proteins inserted by researchers into different cell types. The proteins light up the retina, its photoreceptors (shown in red and yellow) and stem cells called Müller glia (shown in green). Tools such as this one help scientists monitor how Müller glia react to damage in the eye. This helps them determine how the Müller glia can be harnessed to restore vision to human patients with degenerative eye diseases. Follow us.
immune system cells

Failing Immune System ‘Brakes’ Help Explain Type 1 Diabetes

Study in mice on the immune dysfunction of type 1 diabetes points toward new drug targets to treat the disease. Read more.
nano particles

A New Way of Targeting Cancer Cells?

In a “proof of concept” study, scientists have successfully delivered nano-size packets of genetic code called microRNAs to treat human brain tumors implanted in mice. Read more.
virtual hearts

Virtual Hearts to Guide Treatment for Irregular Heartbeats

Scientists have successfully performed 3D personalized virtual simulations of the heart to accurately identify where specialists should destroy cardiac tissue to stop potentially fatal irregular heartbeats in patients with scarring in the heart. Read more.
cells

Defective Pores Inside the Cell May Contribute to Alzheimer’s Disease

Researchers have found that a defect in the nuclear pore complex in animal and human Alzheimer’s disease cells is associated with aggregation of proteins in neurons. Read more.