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Discoveries for a Better Tomorrow


The Hopkins Heart – Robert Higgins, M.D.

Heart failure has enormous costs, but existing therapies are often inadequate. Dr. Robert Higgins explains how a team of physicians, surgeons, engineers and biochemists are developing the next generation of replacement heart –“the Hopkins Heart.”

Therapy for Aortic Aneurysms—Dr. Hal Dietz

Johns Hopkins researchers have identified the genes responsible for aortic ballooning and the sequence of events leading to aortic aneurysms. Dr. Hal Dietz currently conducts clinical trials of therapies for people with inherited aortic aneurysms to improve health and quality of life for these patients.

The Missing Connection Between Heart Failure and Heart Arrhythmias — Dr. Mark Anderson

Heart failure means that the heart is unable to pump enough blood, while heart arrhythmias occur when the heart’s electrical system is disorganized. Dr. Anderson and his team want to understand why heart failure and heart arrhythmias often happen together—and how both can be better prevented.

Tapping into the Heart’s Strategy – Jennifer Lawton, M.D.

Jennifer Lawton, M.D., and her team study a channel in heart cells that opens when energy is low to protect the heart. With more knowledge of the channel, their hope is to be able to open it with medications to reduce harm to the heart following heart surgery, heart attack or times of stress.

Preventing Cardiovascular Disease – Erin Michos, M.D.

Erin Michos, M.D., is a preventive cardiologist and epidemiologist who studies populations to determine new risk factors that may contribute to cardiovascular diseases.

Preventing Heart Failure – David Alan Kass, M.D.

Over the course of his 30 years at Johns Hopkins, David Kass, M.D., has worked to understand why the heart fails and what we can do about it. He and his team developed a pacemaker-like treatment that coordinates the heartbeat. Called cardiac resynchronization, this treatment is now used worldwide.

Tailoring Treatments for Patients with Heart Failure – Pamela Ouyang, M.B.B.S., M.D.

Pamela Ouyang, M.B.B.S., M.D., and her team research specific biochemical pathways that may differ in women and men, and they explain why women are more likely to develop heart failure with preserved ejection fraction.

Heart Attack in a Dish – Dr. Brian O’Rourke

Dr. Brian O’Rourke and his laboratory study how mitochondria, the cellular powerhouses of the heart, contribute to heart attacks and heart failure.

Heart Rhythm Abnormalities – Dr. Hugh Calkins

Over the past three decades, Dr. Hugh Calkins’s research has focused on developing and perfecting a noninvasive technique called catheter ablation to treat heart rhythm abnormalities.

Cardiovascular Imaging | Joao A. C. Lima, M.D., M.B.A.

Joao Lima, M.D., M.B.A., uses specialized imaging to learn more about heart and neurodegenerative diseases.