Research in the Neurofunction Section is focused on the development of novel MRI techniques to evaluate the brain's physiology, function, metabolism, and structure, as well as their clinical applications. Our work spans across humans to animal models and ranges from neonates to elderly individuals. Our central goal is to develop translatable MRI tools as candidate biomarkers in neurologic and psychiatric diseases.
Representative techniques that our team is actively developing include T2-Relaxation-Under-Spin-Tagging (TRUST) to measure oxygenation and oxidative metabolism, cerebrovascular reactivity (CVR) to evaluate the brain’s vascular reserve, water extraction with phase contrast arterial spin tagging (WEPCAST) for non-contrast assessment of BBB permeability, MR fingerprinting arterial spin labeling (MRF-ASL) for multi-parametric hemodynamic imaging, and brain atlases in special populations such as pediatric patients. Our team is looking forward to opportunities of collaboration and welcomes inquiries or requests of our techniques.