Rana Rais is an Assistant Professor of Neurology responsible for conducting drug metabolism and pharmacokinetic evaluation of novel chemical entities as part of the Johns Hopkins Drug Discovery (JHDD) program.
Prior to joining Johns Hopkins, Dr. Rais was granted a Research Science Regulatory (RSR) fellowship at US FDA to evaluate the biopharmaceutic properties of new molecular entities from drug applications.
Dr. Rais received her Ph.D. in Pharmaceutical Sciences with substantial experience in biopharmaceutics, drug permeability, drug transport, drug metabolism, pharmacokinetics, and drug delivery including prodrug design and characterization. Rana now leads a drug metabolism, pharmacokinetic, and bio analysis laboratory and directs this unit as part of the Johns Hopkins Drug Discovery program.
Her laboratory routinely conducts assays essential for determining key pharmaceutic /biopharmaceutic properties including solubility, metabolic stability, plasma protein binding, permeability, plasma pharmacokinetics, and tissue/brain penetration of small molecule-based drugs. In addition, she has utilized her pharmaceutical experience in drug delivery strategies to apply intranasal and prodrug approaches for compounds with limited brain penetration and low intestinal permeability, respectively.