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Margaret Daniele Fallin, Ph.D.

Photo of Dr. Margaret Daniele Fallin, Ph.D.
  • Sylvia and Harold Halpert Professor and Chair, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health
  • Joint Appointment in Medicine

Research Interests

Epidemiology; Genetics; Epigenetics; Genetic epidemiology; Neuropsychiatric disorders; Mental health; Development; Single-nucleotide polymorphism (SNP); Autism; Alzheimer's disease; Schizophrenia; Bipolar disorder more


Dr. M. Daniele Fallin holds a joint appointment in medicine at the Johns Hopkins University School of Medicine. She is the Sylvia and Harold Halpert Professor and chair of the Department of Mental Health at the Johns Hopkins Bloomberg School of Public Health, where she holds joint appointments in biostatistics and genetic epidemiology.

An internationally recognized expert in aging and neuropsychiatric disorders, Dr. Fallin is the director of the Wendy Klag Center for Autism & Developmental Disabilities. She serves on the faculty of the Center for Global Health, Center for Mental Health Initiatives, and Center for Epigenics.

She earned her Ph.D. in genetic epidemiology from Case Western Reserve University. She also holds a B.S. from the University of Florida, Gainesville.

Dr. Fallin joined the Johns Hopkins faculty in 2000. more


  • Sylvia and Harold Halpert Professor and Chair, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health
  • Director, Wendy Klag Center for Autism & Developmental Disabilities
  • Co-Director, Genetics Core, Claude D. Pepper Older Americans Independence Center
  • Joint Appointment in Medicine
  • Joint Appointment in Psychiatry and Behavioral Sciences

Departments / Divisions

Centers & Institutes

Research & Publications

Research Summary

Dr. Fallin’s research focuses on the genetic basis of neuropsychiatric conditions such as autism, Alzheimer's disease, schizophrenia and bipolar disorder, as well as on the integration of genetic susceptibility and environmental risk. Her current work applies genetic epidemiology methods to both the study of these disorders and the development of applications and methods for epigenetic epidemiology, particularly as applied to mental health and development.

Selected Publications

View all on Pubmed

DiGuiseppi CG, Daniels JL, Fallin DM, Rosenberg SA, Schieve LA, Thomas KC, Windham GC, Goss CW, Soke GN, Currie DW, Singer AB, Lee LC, Bernal P, Croen LA, Miller LA, Pinto-Martin JA, Young LM, Schendel DE. "Demographic profile of families and children in the Study to Explore Early Development (SEED): Case-control study of autism spectrum disorder." Disabil Health J. 2016 Jul;9(3):544-51. doi: 10.1016/j.dhjo.2016.01.005. Epub 2016 Jan 29.

Bakulski KM, Feinberg JI, Andrews SV, Yang J, Brown S, L McKenney S, Witter F, Walston J, Feinberg AP, Fallin MD. "DNA methylation of cord blood cell types: Applications for mixed cell birth studies." Epigenetics. 2016 May 3;11(5):354-62. doi: 10.1080/15592294.2016.1161875. Epub 2016 Mar 28.

Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue MW, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hardy J, Hendrie HC, Hall KS, Goate AM, Lang R, Byrd GS, Kukull WA, Foroud TM, Farrer LA, Martin ER, Pericak-Vance MA, Schellenberg GD, Mayeux R, Haines JL, Thornton-Wells TA; Alzheimer Disease Genetics Consortium. "Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk." Alzheimers Dement. 2016 Mar;12(3):233-43. doi: 10.1016/j.jalz.2015.02.012. Epub 2015 Jun 16.

Fallin MD, Duggal P, Beaty TH. "Genetic epidemiology and public health: the evolution from theory to technology." Am J Epidemiol. 2016 Mar 1;183(5):387-93. doi: 10.1093/aje/kww001. Epub 2016 Feb 22.

Ladd-Acosta C, Shu C, Lee BK, Gidaya N, Singer A, Schieve LA, Schendel DE, Jones N, Daniels JL, Windham GC, Newschaffer CJ, Croen LA, Feinberg AP, Daniele Fallin M. "Presence of an epigenetic signature of prenatal cigarette smoke exposure in childhood." Environ Res. 2016 Jan;144(Pt A):139-48. doi: 10.1016/j.envres.2015.11.014. Epub 2015 Nov 21.

Academic Affiliations & Courses

Courses and Syllabi

  • Public Mental Health (330.662.01)
  • Public Health Approaches in Autism and Developmental Disabilities (330.700.01)
  • Autism Spectrum Disorders in Public Health (330.646.11)
  • Applications and Analysis of Epigenetic Data in Public Health Research (330.690.11)
  • Computer Lab: Epigenetic Data in Public Health Research (330.990.11)

Activities & Honors

Professional Activities

  • Co-Director, Genetic Epidemiology Laboratory, Johns Hopkins Bloomberg School of Public Health, 2003
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