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School of Medicine
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Kellie L. Tamashiro, Ph.D.
Associate Professor of Psychiatry and Behavioral Sciences
Research Interests: Stress, depression, obesity, ingestive behavior, eating disorders, Developmental Origins of Health and Disease (DOHaD), epigenetics, neuroendocrinology, animal models ...read more
- Associate Professor of Psychiatry and Behavioral Sciences
Departments / Divisions
- B.B.A., University of Hawaii (Hawaii) (1992)
- Ph.D., University of Cincinnati (Ohio) (2005)
Johns Hopkins University, Baltimore, Maryland, 2008, Psychiatry & Neuroscience
Research & Publications
Our research program focuses on the developmental origins of disease. Stressors, including altered diet, psychosocial stress, immune challenge, during gestation can have adverse consequences on the intrauterine environment and increase disease susceptibility of the developing fetus. The long-term effects on offspring include greater susceptibility to psychiatric disease, such as depression and anxiety disorders, and adverse metabolic conditions including obesity, diabetes and cardiovascular disease. Studies in the laboratory use rodent models and incorporate a multilevel approach to determine the behavioral, physiological, and neural correlates of disease development. Genetic and epigenetic approaches are used to further elucidate molecular mechanisms that may increase susceptibility to psychiatric disease and will facilitate development of diagnostic biomarkers and novel clinical interventions for such conditions.
Another area of interest in the lab is in eating disorders. We use a rat animal model of anorexia (“activity-based anorexia”) to identify the factors that serve to perpetuate and sustain anorexia nervosa-like behavior and increase the likelihood of relapse.
Lab Website: Behavioral Neuroscience Laboratory
Academic Affiliations & Courses
Graduate Program Affiliation
Faculty, Cellular & Molecular Medicine Graduate Program
Activities & Honors
- Fellowship, Albert J. Ryan Foundation, 2002 - 2004
- Omicron Delta Kappa National Leadership Honor Society, 2004
- Alan N. Epstein Research Award, Society for the Study of Ingestive Behavior, 2014
- Ethan Sims Young Investigator Award Finalist, The Obesity Society, 2007
- Pre-Doctoral Fellow, Training Grant in Neuroendocrinology (T32 DK-59803), 2003 - 2004
- Post-Doctoral Fellow, Training Grant in Psychiatry & Neuroscience (T32 MH-15330), 2005 - 2006
- Fellowship, University Distinguished Graduate, 2000 - 2003
- Society for Neuroscience
- Society for the Study of Ingestive Behavior
- The Obesity Society
Videos & Media
Lectures and Presentations
Developmental Origins of Health and Disease
Grand Rounds Lectures, Baltimore, MD (12/01/2013)
Johns Hopkins Department of Psychiatry & Behavioral Sciences
Recent News Articles and Media Coverage
Poor prenatal nutrition linked to negative metabolic changes, obesity, American Diabetes Association, Diabetes Dispatch, June 16, 2014
Hope for Staying Off the Fat Track, Hopkins Brain Wise, Spring 2014
Happy Thanksgiving: If Kids Exercise, They Are Not Doomed By Maternal Epigenetics To Be Obese, Science 2.0, November 28, 2013
Olanzapine? Can't Say No to Dough, Hopkins Brain Wise, Winter 2012