Dr. Peter J. Espenshade is a professor of cell biology at the Johns Hopkins University School of Medicine. He also serves as director of the Center for Innovation in Graduate Biomedical Education.
The Espenshade Lab studies the mechanisms of molecular sensing, including the regulation of cellular cholesterol homeostasis and the cellular response to hypoxia.
Dr. Espenshade currently serves as the principal investigator (PI) of both an American Heart Association-funded study of prolyl hydroxylase Ofd1 and a National Institute of Allergy and Infectious Disease-funded study of the mechanisms of host adaptation for candida albicans. He also served as PI of two externally funded studies that concluded in 2014. One examined the regulation of cellular cholesterol homeostasis; the other looked at the SREBP pathway as a target for pancreatic cancer therapy.
Dr. Espenshade earned an A.B. in molecular biology from Princeton University. He earned his Ph.D. in cell biology/genetics from the Massachusetts Institute of Technology before completing postdoctoral training in molecular cell biology at UT Southwestern Medical Center in Dallas. Dr. Espenshade joined the Johns Hopkins faculty as an Assistant Professor in 2003.
Dr. Espenshade has published more than 40 journal articles and contributed chapters to four books, including The Encyclopedia of Biological Chemistry and The Johns Hopkins Textbook of Dyslipidemia. He has received many professional honors, including the 2012 Avanti Young Investigator Award in Lipid Research by the American Society for Biochemistry and Molecular Biology.