Dr. Geraldine Seydoux is the Huntington Sheldon Professor in Medical Discovery in the Department of Molecular Biology and Genetics at the Johns Hopkins University School of Medicine and an investigator with the Howard Hughes Medical Institute. Her work examines how early embryos develop into complex asymmetric structures comprising many cell types.
Seydoux is best known for finding that global inhibition of mRNA synthesis is an essential first step in the establishment of the germline. Currently, her lab is studying a family of intrinsically-disordered proteins that scaffold RNA granules. The Seydoux lab is also developing new methods for genome editing using CRISPR technology.
Dr. Seydoux received her B.S. in biochemistry from the University of Maine at Orono in 1986, and completed her Ph.D. in molecular biology at Princeton University in 1991. After a postdoctoral fellowship in developmental biology at the Carnegie Institute of Washington, she joined the faculty of Johns Hopkins in 1995 as an assistant professor. She became an associate professor in 2000, and a full professor in 2005.
Dr. Seydoux's work has garnered several awards, including a MacArthur Fellowship in 2001. She was elected to the American Academy of Arts and Sciences in 2013 and to the National Academy of Sciences in 2016. She assumed the role of vice dean for Basic Research at the Johns Hopkins School of Medicine in 2017.