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Arvind P. Pathak, Ph.D.

Photo of Dr. Arvind P. Pathak, Ph.D.
  • Associate Professor of Radiology and Radiological Science
Male

Research Interests

Functional and Molecular Imaging; Systems Biology; Tumor Microenvironment; Multiscale Imaging; Computational and Visualization Tools; Tissue Engineering ...read more

Background

Dr. Arvind P. Pathak is Associate Professor of Radiology and Oncology at the Johns Hopkins University School of Medicine and a member of the Johns Hopkins Kimmel Cancer Center. His work focuses on developing new imaging methods, computational models and visualization tools to ‘make visible’ critical aspects of cancer, neurobiology and tissue engineering.

Dr. Pathak received his BS in electronics engineering from the University of Poona, India, in 1993, and in 2001 completed his PhD in Functional Imaging from the joint graduate program between the Biophysics Department at the Medical College of Wisconsin and the Biomedical Engineering Dept at Marquette University. During his PhD he was the recipient of a Whitaker Fellowship. After a postdoctoral fellowship in the Molecular Imaging Program at Johns Hopkins University, he joined the Johns Hopkins faculty in 2003.

Dr. Pathak's research has been recognized by several awards and journal covers. These include the Bill Negendank Young Investigator Award from the International Society for Magnetic Resonance in Medicine (ISMRM) given to “outstanding young investigators in the field of cancer MR” and the ISMRM's Outstanding Teacher Award for 2014. He has advised over sixty students and is a much sought after mentor.

...read more

Titles

  • Associate Professor of Radiology and Radiological Science
  • Associate Professor of Biomedical Engineering
  • Associate Professor of Oncology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • Ph.D., Medical College of Wisconsin - Milwaukee (Wisconsin) (2001)

Additional Training

Radiological Sciences, Johns Hopkins University, Baltimore, MD, 2003, Postdoctoral Fellowship

Research & Publications

Research Summary

Dr. Pathak’s lab employs biomedical imaging, computational models and visualization tools to answer critical questions in cancer, neuroscience and tissue engineering. Specifically, his team investigates the microenvironment of tumors with the goal of developing clinical biomarkers and a deeper understanding of disease progression and metastasis. The Pathak lab also develops miniaturized microscopes and optical imaging methods to interrogate brain function in health and disease. Finally, they also use imaging to inform the development of tissue engineered constructs.

Lab

Visit his laboratory:

www.pathaklab.org

Lab Website: Pathak Laboratory

Selected Publications

View all on Pubmed

Assessing breast cancer angiogenesis in vivo: which susceptibility contrast MRI biomarkers are relevant?
Kim E, Cebulla J, Ward BD, Rhie K, Zhang J, Pathak AP. Magn Reson Med. 2013 Oct;70(4):1106-16. doi: 10.1002/mrm.24530. Epub 2012 Dec 6.

Multiscale imaging and computational modeling of blood flow in the tumor vasculature.
Kim E, Stamatelos S, Cebulla J, Bhujwalla ZM, Popel AS, Pathak AP.
Ann Biomed Eng. 2012 Nov;40(11):2425-41. doi: 10.1007/s10439-012-0585-5. Epub 2012 May 8. Review.

Vascular phenotyping of brain tumors using magnetic resonance microscopy (μMRI).
Kim E, Zhang J, Hong K, Benoit NE, Pathak AP.
J Cereb Blood Flow Metab. 2011 Jul;31(7):1623-36. doi: 10.1038/jcbfm.2011.17. Epub 2011 Mar 9. Erratum in: J Cereb Blood Flow Metab. 2011 Aug;31(8):1817-8

Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area, and invasive phenotype.
Pathak AP, Artemov D, Neeman M, Bhujwalla ZM.
Cancer Res. 2006 May 15;66(10):5151-8.

Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by magnetic resonance imaging.
Pathak AP, Artemov D, Ward BD, Jackson DG, Neeman M, Bhujwalla ZM.
Cancer Res. 2005 Feb 15;65(4):1425-32.

Activities & Honors

Honors

  • The Bill Negendank Young Investigator Award First Place for Outstanding Young Investigators in the Field of Cancer MR, Awarded by the International Society for Magnetic Resonance in Medicine, 2002
  • Student Travel Award, Bioengineering Section of the American Society of Mechanical Engineering, 1996
  • Elmer L. Lindseth Lectureship, Case Western Reserve University, 2005
  • Student Stipend Awards, International Society for Magnetic Resonance in Medicine, 1998 - 2003
  • Provost’s Undergraduate Research Award, Johns Hopkins University
  • The Andrew Moissoff Young Investigator Award, Lymphatic Research Foundation, 2004
  • Research Assistantship, Marquette University, 1994
  • Whitaker Foundation Functional Imaging Fellowship, Marquette University and Biophysics Research Institute, 1997
  • Journal Publication Award, Medical College of Wisconsin Cancer Center Trainee Paper Competition, 2001
  • Junior Faculty Pilot Project Award, Johns Hopkins Institute for Nanobiotechnology, 2010
  • Susan Komen Career Catalyst Award in Breast Cancer, 2009
  • Young Investigator Scholarship/Awarded by the Lymphatic Research Foundation, The Susan G. Komen Breast Cancer Foundation, 2004

Memberships

  • World Molecular Imaging Society
  • International Society for Magnetic Resonance in Medicine (ISMRM)

Videos & Media

Recent News Articles and Media Coverage

Mini Microscope is the New GoPro for Studies of Brain Disease in Living Mice, Johns Hopkins Medicine News Releases (03/27/2019)

‘Google Maps’ for Cancer: Image-Based Computer Model Reveals Finer Details of Tumor Blood Flow Behavior, Johns Hopkins Medicine News Releases (05/06/2019)

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