Background
Titles
- Associate Professor of Surgery
- Associate Professor of Surgery
Research Interests
Pulmonary Infectious and Inflammatory Diseases; Renin-Angiotensin System; Stem Cell Biology; Immunology ...read more
Hongpeng Jia, M.D., M.Sc.
Education
Degrees
- M.D.; Hebei Medical University - Shijiazhuang (China) (1987)
- M.Sc.; Peking Union Medical College (China) (1990)
Research & Publications
Technology Expertise Keywords
Molecular Biology, immunology, virology, Stem cell biology, small animal models of infectious and inflammatory lung diseases
Selected Publications
Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB Jr. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol. 2005 Dec;79(23):14614-21. doi: 10.1128/JVI.79.23.14614-14621.2005. PubMed PMID: 16282461; PubMed Central PMCID: PMC1287568
Jia H. Pulmonary Angiotensin-Converting Enzyme 2 (ACE2) and Inflammatory Lung Disease. Shock.2016 Sep;46(3):239-48. doi:
Sodhi CP, Wohlford-Lenane C, Yamaguchi Y, Prindle T, Fulton WB, Wang S, McCray PB Jr, Chappell M, Hackam DJ, Jia H. Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration. Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L17-L31. doi: 10.1152/ajplung.00498.2016. Epub 2017 Sep 21. PubMed PMID: 28935640; PubMed Central PMCID: PMC5866432
Sodhi CP, Nguyen J, Yamaguchi Y, Werts AD, Lu P, Ladd MR, Fulton WB, Kovler ML, Wang S, Prindle T Jr, Zhang Y, Lazartigues ED, Holtzman MJ, Alcorn JF, Hackam DJ, Jia H. A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice. J Immunol. 2019 Dec 1;203(11):3000-3012. doi: 10.4049/jimmunol.1900579. Epub 2019 Oct 23. PubMed PMID: 31645418; PubMed Central PMCID: PMC7458157
Jia H, Yue X, Lazartigues E. ACE2 mouse models: a toolbox for cardiovascular and pulmonary research. Nat Commun. 2020 Oct 14;11(1):5165. doi: 10.1038/s41467-020-18880-0. Review. PubMed PMID: 33057007; PubMed Central PMCID: PMC7560817
Contact for Research Inquiries
735A Ross Building
1721 E Madison Street
Baltimore, MD 21205 map
Activities & Honors
Memberships
- International Endotoxin and Innate Immunity Society, American Thoracic Society, American Heart Association, International Shock Society
Patient Ratings & Comments
The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.