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Christine Anne Pratilas, M.D.

Photo of Dr. Christine Anne Pratilas, M.D.

Assistant Professor of Oncology

Specializes in: Infants (up to 1 year), Adolescents (12-18 years)


Expertise: Bone Cancer, Bone Tumors, Chemotherapy, Clinical Trials, Ewing's Sarcoma, Medical Oncology, Melanoma, Osteosarcoma, Pediatric Cancer, Pediatric Oncology, Rhabdomyosarcoma, Sarcoma, Sarcoma and Musculoskeletal Tumors , Soft Tissue Sarcoma, Soft Tissue Tumors more

Research Interests: oncogenes; BRAF mutations; cancer cell signaling pathways; molecularly targeted therapy; RAF and MEK inhibitor therapy; pediatric sarcomas; pediatric phase I clinical trials more

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The Johns Hopkins Hospital (Main Entrance)
Appointment Phone: 410-955-8751

1800 Orleans St.
The Charlotte R. Bloomberg Children's Center Building, 11th Floor
Baltimore, MD 21287 map


Dr. Christine Pratilas is a hematologist and medical oncologist at the Sidney Kimmel Comprehensive Cancer Center and an Assistant Professor of Oncology and Pediatrics at the Johns Hopkins University School of Medicine. She joined the Hopkins pediatric sarcoma/solid tumor team in 2014.

Dr. Pratilas received her undergraduate degree in Biology from Drew University in New Jersey and her medical degree from the Robert Wood Johnson Medical School, where she completed her internship and residency between 1999 and 2002. From 2002 to 2005 she was a fellow in hematology and oncology in the Memorial Sloan Kettering Cancer Center (MSKCC) Department of Pediatrics, and in the Department of Pediatric Hematology and Oncology at New York Weill Cornell Medical Center. She also worked for three years as a postdoctoral research fellow in Dr. Neal Rosen’s Molecular Oncogenesis Laboratory at MSKCC. 

From 2006 to 2014 she attended on the Pediatric Oncology unit at MSKCC, supervising the care of children while overseeing the work of fellows, residents, and nurse practitioners. In 2011 she began her specialization in the care of pediatric sarcoma patients, overseeing their care in a weekly clinic.

During her years in the lab of Dr. Rosen, a distinguished molecular geneticist, Dr. Pratilas focused her research on signal transduction, which involves figuring out how a cell’s internal molecular pathways work, and how those pathways can be molecularly controlled. This knowledge is the basis for developing promising new molecularly targeted cancer therapies, which is the focus of Dr. Pratilas’s research. One of her most important contributions to date has been to advance our understanding of how certain proteins that can be mutated in cancer known as RAF kinases affect a cancer cell’s behavior.

Dr. Pratilas continues her research on signal transduction pathways, concentrating on pediatric sarcomas, in order to develop novel therapeutics for children with these tumors. more


  • Assistant Professor of Oncology

Departments / Divisions



  • MD; Pediatrics, Rutgers - Robert Wood Johnson Medical School (1999)


  • Robert Wood Johnson University Hospital / Pediatrics (2002)


  • Memorial Sloan-Kettering Cancer Center / Hematology and Oncology (2005)

Board Certifications

  • American Board of Pediatrics / Pediatric Hematology (2006)
  • American Board of Pediatrics / Pediatrics - General (2002)

Additional Training

  • 2015 (exp.) DEA

Research & Publications


10/12/10 Awarded, Biomarkers for Cancer Treatment - U.S. Patent No. 7,812,143 B2; Inventors: Pratilas, C; Rosen, N
Patent # U.S. Patent No. 7,812,143 B2 | 10/12/2010

Activities & Honors


  • Young Investigator Award, Melanoma Research Alliance, 2011
  • ASCO Foundation Young Investigators Award, 2004
  • AACR Scholar-in-Training Award, 2004
  • Doris Duke Award, MSKCC, 2004
  • Medical Society Scholarship, Morris County, NJ, 1997
  • Magna cum laude, Phi Beta Kappa, Drew University, 1995
  • Merit Scholarship, Drew University, 1992 - 1995
  • Edward Bloustein Garden State Scholarship, New Jersey, 1992 - 1995


  • American Association for Cancer Research, 2003
  • American Society of Clinical Oncology, 2003
  • Pediatric Oncology Experimental Therapeutics Investigators Consortium, 2006 - 2014
  • Children’s Oncology Group, 2008
  • AACR Pediatric Cancer Working Group, 2012
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