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Maureen A. Lefton-Greif, M.A., Ph.D.

Photo of Dr. Maureen A. Lefton-Greif, M.A., Ph.D.

Director, Johns Hopkins Feeding/Swallowing Disorders Program

Professor of Pediatrics

Specializes in: Children (1-11 years), Infants (up to 1 year), Adolescents (12-18 years)

Expertise: Dysphagia, Swallowing Disorders

Research Interests: Oropharyngeal dysphagia in infants and children, development of standardized Videofluoroscopic Swallow Study procedures and outcome measures, development of respiratory-swallow coordination, respiratory-swallow coordination in Ataxia-Telangiectasia and Neuromuscular Disorders, aspiration-induced lung disease, aerodigestive disorders in infants and children ...read more

Contact for Research Inquiries

The Johns Hopkins Hospital
200 N. Wolfe Street
Baltimore, MD 21287 map

Background

Dr. Maureen A. Lefton-Greif is a Professor of Pediatrics, Otolaryngology Head and Neck Surgery, and Physical Medicine and Rehabilitation at the Johns Hopkins University School of Medicine.  Her areas of clinical expertise include feeding/swallowing development and disorders.  Her research focuses on standardization of fluoroscopic images from bottle-fed children with dysphagia and respiratory-swallow coordination in progressive diseases with pediatric origins.

Dr. Lefton-Greif co-authored the book dedicated to Videofluoroscopic Swallow Studies in infants and young children. She is a board certified specialist in swallowing and swallowing disorders, and serves on the editorial advisory boards of the Journal of Dysphagia, the Canadian Journal of Speech-Language Pathology and Audiology, and American Journal of Speech-Language Pathology. She is an active member of the Dysphagia Research Society. 

As a nationally and internationally renowned clinician, Dr. Lefton-Greif has served on multidisciplinary, graduate education, and clinical practice guidelines committees. Her work has changed standards of clinical care including diagnostic, surveillance, and management protocols; improved the outcomes and survival of affected children; and resulted in clinical referrals beyond the local/regional area.  Her clinical opinions, expertise, and instruction have been requested here and abroad.

 

 

 

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Titles

  • Director, Johns Hopkins Feeding/Swallowing Disorders Program
  • Professor of Pediatrics
  • Associate Professor of Physical Medicine and Rehabilitation
  • Professor of Otolaryngology - Head and Neck Surgery

Education

Degrees

  • B.A., Brooklyn College of the City University of New York (New York) (1972)
  • M.A., Case Western Reserve University (Ohio) (1973)
  • Ph.D., Temple University (Pennsylvania) (1988)

Additional Training

  • Certificate of Clinical Competence in Speech-Language Pathology, American Speech-Language Hearing Association (ASHA)

Research & Publications

Research Summary

Dr. Lefton-Greif’s research focuses on standardization of protocols and images from bottle-fed children with dysphagia and respiratory-swallow coordination in progressive diseases with pediatric origins.

Her publications were the first to identify the presence of oropharyngeal dysphagia in children with unexplained respiratory presentations; identify dysphagia as a significant contributor to respiratory compromise in Ataxia-Telangiectasia, which is the leading cause of death and had been previously attributed to immunologic problems; and report on a novel scale that quantifies the impact on caregivers of feeding/swallowing problems in their children.

Selected Publications

View all on Pubmed

1. Lefton-Greif MA, Crawford TO, Winkelstein JA, Loughlin GM, Koerner CB, Zahurak M, Lederman HM. Oropharyngeal dysphagia and aspiration in patients with Ataxia-Telangiectasia. J Pediatrics. 2000;136(2):225-231.

2. Crawford TO, Mandir, AS, Lefton-Greif MA, Goodman, SN, Goodman B.K, Sengul H, Lederman HM. Quantitative neurologic assessment of ataxia-telangiectasia. Neurology. 2000; 54:1505-1509.

3. Lefton-Greif MA, Carroll JL, Loughlin GM. Long-Term Follow-Up of Oropharyngeal Dysphagia in Children without Apparent Risk Factors. Pediatr Pulmonol. 2006; 41(11): 1040-1048.

4. Lefton-Greif MA, Crawford TO, McGrath-Morrow S A, Carson KA, Lederman HM. Safety and caregiver satisfaction with gastrostomy in patients with Ataxia Telangiectasia. Orphanet J Rare Diseases. 2011 May 15;6(1):23.

5. McGrath-Morrow SA, Ryan T, Riekert K, Lefton-Greif MA, Eakin M, Collaco JM. The impact of bronchopulmonary dysplasia on caregiver health related quality of life during the first 2 years of life. Pediatr Pulmonol. 2013. 48:579-586.

6. Lefton-Greif MA, Okelo SO, Wright JM, Collaco JM, McGrath-Morrow SA, Eakin MN. Impact of Children's Feeding/Swallowing Problems: Validation of a New Caregiver Instrument. Dysphagia. 2014 Aug27. December; 29(6):671-677.

7. Collaco JM, Aherrera AD, Au Yeung KJ, Lefton-Greif MA, Hoch J, Skinner ML. Interdisciplinary Pediatric Aerodigestive Care and Reduction in Health Care Costs and Burden. JAMA Otolaryngol Head Neck Surg. 2015.141:101-105.

8. Leder SB, Siner JM, Bizzarro MJ, McGinley BM, Lefton-Greif MA. Oral Alimentation in Neonatal and Adult Populations Requiring High-Flow Oxygen via Nasal Cannula. Dysphagia Dysphagia. 2016 Apr;31(2):154-9. doi: 10.1007/s00455-015-9669-3. Epub 2015 Nov 21.

9. Skinner ML, Lee SK, Collaco JM, Lefton-Greif MA, Hoch J, Au Yeung KJ (2016) Financial and Health Impacts of Multidisciplinary Aerodigestive Care. Otolaryngol Head Neck Surg 154 (6):1064-1067. doi:10.1177/0194599816637830

10. Flax-Goldenberg R, Kulkani KS, Carson KA, Pinto JM, Martin-Harris B, Lefton-Greif MA. Concordance Between Aspiration Detected on Upper Gastrointestinal Series and Videofluoroscopic Swallow Study in Bottle-Fed Children. Dysphagia. 2016 Aug;31(4):505-10. doi: 10.1007/s00455-016-9705-y. Epub 2016 Apr 6.

11. Lefton-Greif MA, Perlman AL, He X, Lederman HM, Crawford TO. Assessment of Impaired Coordination between Respiration and Deglutition in Children and Young Adults with Ataxia Telangiectasia. Developmental Medicine & Child Neurology. 2016 Oct;58(10):1069-75. doi: 10.1111/dmcn.13156. Epub 2016 May 23.

McGrattan K, McGhee H, DeToma A, Hill EG, Zyblewski SC, Lefton-Greif MA, Halstead L, Bradley S, Martin-Harris B. Dysphagia in Infants with Single Ventricle Anatomy Following Stage 1 Palliation: Physiologic Correlates and Response to Treatment. Congential Heart Disease. 2017 Feb 28. doi: 10.1111/chd.12456. [Epub ahead of print]

Activities & Honors

Honors

  • Certificate of Honor, College of Health Professionals Alumni Association, Temple University
  • Scientific Abstract Oral Presentation Winner, Dysphagia Society
  • National Foundation of Swallowing Disorders Award
  • 15th Award for Continuing Education, American Speech-Language Hearing Association
  • Mentor for Student Research Travel Award, American Speech-Language Hearing Association

Memberships

  • Dysphagia Research Society
  • American Speech-Language-Hearing Association
  • Society for Ear, Nose and Throat Advances in Children
  • Maryland Speech-Language Hearing Association

Professional Activities

  • Editorial Advisory Board Member, An International Multidisciplinary Journal Devoted to Swallowing and Its Disorders
  • Editorial Review Board Member, Canadian Journal of Speech-Language Pathology and Audiology
  • Editorial Board Member, American Journal of Speech-Language Pathology
  • Mentor - Student Research Travel Award Recipient, American Speech-Language Hearing Association (2009)
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