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Nestoras Nicolas Mathioudakis, M.D., M.H.S.

Photo of Dr. Nestoras Nicolas Mathioudakis, M.D., M.H.S.
  • Clinical Director, Endocrinology, Diabetes, & Metabolism
  • Associate Professor of Medicine
Male

Languages: English, French, Greek

Expertise

Continuous Glucose Monitoring, Diabetes, Diabetes Mellitus, Diabetic Foot Ulcers, Endocrinology, Hypoglycemia, Insulin Pump, Insulinoma

Research Interests

Patient Safety and Quality; Inpatient Glucose Management; Type 2 Diabetes Mellitus; Diabetic Foot Ulcers; Type 1 Diabetes; Diabetes Technology; Machine Learning; Clinical Decision Support Systems ...read more

Locations

Johns Hopkins Medicine - Green Spring Station

10751 Falls Road
Falls Concourse Suite 412
Lutherville, MD 21093 map
Phone: 410-955-9270

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-9270
601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 410-955-2908 | Fax: 410-614-9586

Background

A board-certified endocrinologist, Dr. Mathioudakis focuses his clinical practice on the care of patients with endocrine disorders, with a particular clinical interest and research focus on diabetes mellitus.   His main research focus is on discovering ways to improve patient safety and quality among hospitalized patients with diabetes.  He is the Endocrine Director of the Johns Hopkins Multidisciplinary Diabetic Foot and Wound Clinic and is actively investigating the causes and treatment of diabetic foot ulcers.  In addition, Dr. Mathioudakis has a basic science and clinical research background in pituitary tumors.  Dr. Nestoras Mathioudakis graduated from the Johns Hopkins University School of Medicine and trained in Internal Medicine at Johns Hopkins Bayview Medical Center.  He did a fellowship in Endocrinology, Diabetes, & Metabolism at the Johns Hopkins Hospital and then joined the faculty in this division in 2012. Dr. Mathioudakis received his Master of Health Science degree in clinical investigation from the Johns Hopkins Bloomberg School of Public Health in 2015.  He is currently the recipient of an NIH funded grant to develop and evaluate a real-time informatics alert for prevention of insulin-associated hypoglycemia in hospitalized patients.

...read more

Titles

  • Clinical Director, Endocrinology, Diabetes, & Metabolism
  • Core Faculty, Armstrong Institute for Patient Safety and Quality
  • Associate Professor of Medicine

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD, Johns Hopkins University School of Medicine (2006)

Residencies

  • Johns Hopkins Bayview Medical Center / Internal Medicine (2009)

Fellowships

  • Johns Hopkins University School of Medicine / Endocrinology (2012)

Board Certifications

  • American Board of Internal Medicine / Endocrinology/Diabetes/Metabolism (2011)

Research & Publications

Lab

Our lab is focused on improving the safety and quality of care for patients with diabetes mellitus.

Lab Website: Nestoras Mathioudakis Lab

Technology Expertise Keywords

Machine Learning; Continuous Glucose Monitoring; Insulin Pumps

Clinical Trial Keywords

diabetes prevention

Clinical Trials

  • Diabetes Prevention Program Outcomes Study (DPPOS), Co-PI
  • Digital vs. In-Person Diabetes Prevention Program (R01), PI

Selected Publications

View all on Pubmed

Ashok A, Abusamaan MS, Parker P, Pilla SJ, Mathioudakis NN. Provider Response to Critical Action Values for Hypoglycemia in the Ambulatory Setting: A Retrospective Cohort Study. J Gen Intern Med 2020 Sept 15.

Lane KL, Abusamaan MS, Voss BF, Thurber EG, Al-Hajri N, Gopakumar S, Le JT, Gill S, Blanck J, Prichett L, Hicks CW, Sherman RL, Abularrage CJ, Mathioudakis NN. Glycemic control and diabetic foot ulcer outcomes: A systematic review and meta-analysis of observational studies. J Diabetes Complications. 2020 May

Mathioudakis N, Jeun R, Godwin G, Perschke A, Yalamanchi S, Everett E, Greene P, Knight A, Yuan C, Golden SH. Development and Implementation of a Subcutaneous Insulin Clinical Decision Support Tool for Hospitalized Patients. J Diabetes Sci Technol. 2018 Sept 10

Mathioudakis NN, Everett E, Routh S, Pronovost PJ, Yeh HC, Golden SH, and Saria S. Development and validation of a prediction model for insulin-associated hypoglycemia in non-critically ill hospitalized adults. BMJ Open Diabetes Research and Care 2018;6:e000499. doi: 10.1136/bmjdrc-2017-000499

Mathioudakis N, Everett E, Golden SH. Prevention and Management of Insulin-Associated Hypoglycemia in Hospitalized Patients. Endocr Pract. 2016;22(8):959-969

Contact for Research Inquiries

Phone: 410-502-8089

Academic Affiliations & Courses

Courses and Syllabi

  • Thyroid Disorders
    Lecturer
    2012 - 2013
  • Diabetes Management
    Lecturer
    2012 - 2012
  • Hyperglycemic Emergencies
    Lecturer
    2012
  • Thyroid Nodules and Thyroid Cancer
    Genes to Society- Endocrinology
    2012 - 2012
  • Diabetes Mellitus
    Small group instructor
    2012
  • Endocrinology (Genes to Society - Year 2 Course)
    Small group instructor
    2012
  • Epidemiology (Genes to Society- Year 1 Course)
    Small group instructor
    2018

Activities & Honors

Honors

  • Phi Beta Kappa, Johns Hopkins University, 1999
  • Leonie Shorey Scholar, Johns Hopkins University, 2001
  • Departmental Honors, Johns Hopkins University, 2001
  • First Place Oral Clinical Vignette, American College of Physicians, 2009
  • Endocrinology Mentor of the Year Award, 2012
  • Elected to Epic Endocrinology National Steering Board, Epic, 2017
  • Baltimore Top Doctor 2018, Endocrinology, 2018
  • Nominated Clinical Member to the national Merit-Based Incentive Program (MIPS) of the Center for Medicare and Medicaid Service (CMS) for development of two outpatient diabetes quality measures, 2018
  • Elected Member, Alpha Omega Alpha Medical Honor Society, 2020

Memberships

  • American Association of Clinical Endocrinologists (AACE)
  • American Diabetes Association (ADA), 2012
  • Endocrine Society, 2011
  • PRIDE (Planning Research in Inpatient Diabetes), 2012
  • Journal of Diabetes and Its Complications, 2020

    Editorial Board Member

Professional Activities

  • Attending Physician, Endocrinology Consultation Service, Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center, 2012
  • Consulting physician, General Endocrinology Outpatient Clinic, Johns Hopkins Outpatient Center, Green Spring Station, 2012
  • Diabetes Center Outpatient Clinics
  • Education (medical students, residents, fellows)
  • Preceptor, Johns Hopkins Endocrinology, Diabetes & Metabolism Fellows' Outpatient Clinic

Videos & Media

Lectures and Presentations

  • Ectopic ACTH syndrome
    Maryland Endocrine Society Meeting, Baltimore, MD (02/01/2011)
    Union Memorial Hospital
  • Prevention of Type 2 Diabetes Mellitus in 2013
    Lecture to Employees and clients of Butterfield Bank, Bermuda (05/01/2013)
    Butterfield Bank
  • Insulin Therapy in Type 2 Diabetes
    Department of Medicine Grand Rounds, Kuwait (09/01/2012)
    Al Adan Hospital
  • Principles in Insulin Pump Management
    Department of Medicine Grand Rounds, Kuwait (09/01/2012)
    Al Adan Hospital
  • Diabetic Nephropathy: Current Understanding and Standards of Care
    Endocrine Grand Rounds, Baltimore, MD (10/01/2012)
    Johns Hopkins Hospital
  • Prevention of Type 2 Diabetes in 2013
    Medical Grand Rounds, San Fernando, Trinidad and Tobago (01/01/2012)
    San Fernando General Hospital
  • Top 10 Inpatient Glycemic Management Errors at Johns Hopkins Hospital in 2012
    Endocrine Grand Rounds, Baltimore, MD (04/01/2013)
    Johns Hopkins Hospital
  • Medical Strategies for the Diabetic Foot Ulcer
    Endocrine Grand Rounds, Baltimore, MD (10/01/2013)
    Johns Hopkins Hospital
  • Insulin Therapy in Type 2 Diabetes
    Department of Medicine Grand Rounds, Kuwait (01/01/2012)
    Al Adan Hospital
  • Principles in Insulin Pump Management
    Department of Medicine Grand Rounds, Kuwait (01/01/2012)
    Al Adan Hospital
  • Diabetic Nephropathy, Current Understanding and Standards of Care
    Endocrine Grand Rounds, Baltimore (01/01/2012)
    Johns Hopkins Hospital
  • Prevention of Type 2 Diabetes in 2013
    Medical Grand Rounds, San Fernando (01/01/2012)
    San Fernando General Hospital
  • Top 10 Inpatient Glycemic Management Errors at Johns Hopkins Hospital in 2012
    Endocrine Grand Rounds, Baltimore (01/01/2013)
    Johns Hopkins Hospital
  • Medical Strategies for the Diabetic Foot Ulcer
    Endocrine Grand Rounds, Baltimore (01/01/2013)
    Johns Hopkins Hospital
  • Insulin-Associated Hypoglycemia
    Invited Talk, Grand Rounds, Department of Medicine, Johns Hopkins Hospital (01/15/2016)
    Johns Hopkins University
  • Insulin-Associated Hypoglycemia in the Hospital
    Invited Talk, Grand Rounds, Medical Grand Rounds, Bayview Medical Center (01/26/2016)
    Johns Hopkins University
  • Diabetic Foot Ulcers: Prevention and Treatment Strategies
    Invited Talk, Grand Rounds, Endocrine Grand Rounds, Johns Hopkins Hospital (01/28/2016)
    Johns Hopkins University
  • Weight Loss Strategies for Diabetes Prevention and Management
    Invited Talk, CME, Maryland Chapter Scientific Meeting, Ellicott City, Maryland (02/17/2017)
    American College of Physicians
  • Predicting Insulin-Associated Hypoglycemia in Hospitalized Patients- Moving Towards a Real-Time Alerting System
    Invited Talk, Grand Rounds, Endocrine Grand Rounds, Johns Hopkins Hospital (02/07/2018)
    Johns Hopkins University
  • Racial Differences of AKI of Hospitalized Adults with Diabetes
    Invited Talk, Scientific Meeting, American Association of Clinical Endocrinologists Scientific Meeting, Nashville, TN (05/07/2015)
    AACE
  • Development of an Ambulatory Medication Smartset
    Invited Talk, Scientific Meeting, Epic User Group Meeting, Verona, WI (09/19/2016)
    Epic
  • Glucose Management in the Hospital: From Clinical Care to Systems Interventions
    Invited Talk, Scientific Meeting, Quality Improvement Workshop of Inpatient Blood Glucose Management, Beijing, China (03/20/2015)
    Peking University
  • Real-Time Model of Insulin-Associated Hypoglycemia
    Invited Talk, Scientific Meeting, 77th Scientific Session, San Diego, CA (06/09/2017)
    American Diabetes Association

Recent News Articles and Media Coverage

  • The pancreas loses 40 percent of its function at the pre-diabetic stage, The Royal Gazette (May 14, 2013)
  • Physicians must clearly inform patients with diabetes risks for ketoacidosis when using SGLT2 inhibitors, Healio (September 5, 2016)
  • Hospitals work to improve inpatient diabetes management, Healio (July 2015)
  • Diabetes and the flu. "Flu Streak." WebMD (November 2013)
  • Five Terrifying Signs of Diabetes You Probably Don't Know About  MensHealth (April 2018)
  • Researcher Spotlight: Nestoras Mathioudakis, MD MHS. Practical Diabetology (Jan 2019)
  • Hemoglobin A1C and Wound Healing unrelated in diabetic foot ulcers.  Endocrinology Advisor (May, 2018)
  • What are ketones? Prevention.com (June, 2018)
  • Insulin is getting so expensive that people with diabetes are switching to older versions of the drug.  It's having deadly consequences. INSIDER (August 16, 2019)

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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