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Alvaro Ordonez, M.D.

Photo of Dr. Alvaro Ordonez, M.D.
  • Assistant Professor of Pediatrics

Background

Dr. Alvaro Ordonez is an Assistant Professor of Pediatrics at the Johns Hopkins University School of Medicine. 

After earning his medical degree at the Universidad Industrial de Santander in Colombia, Dr. Ordonez completed a post-doctoral fellowship at Johns Hopkins School of Medicine. He joined the faculty of the Division of Pediatric Infectious Diseases and the Center for Tuberculosis Research in 2018.

His research interests include molecular imaging of bacterial and viral infections, the evaluation of host-directed therapies to modulate the infection-associated inflammatory response, and the use of PET imaging to characterize the intralesional pharmacokinetics of antibiotics. He has led the development of bacteria-specific molecular imaging agents to allow longitudinal, noninvasive assessments and provide key information about infectious processes deep within the body.

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Titles

  • Assistant Professor of Pediatrics

Departments / Divisions

Centers & Institutes

Education

Degrees

  • M.D., Universidad Indust Santander - Division de Ciencias de la Salud - Bucaramanga (Colombia) (2011)

Research & Publications

Selected Publications

View all on Pubmed

Ordonez AA, Wang H, Magombedze G, Ruiz-Bedoya CA, Srivastava S, Chen A, Tucker EW, Urbanowski ME, Pieterse L, Cardozo EF, Lodge MA, Shah MR, Holt DP, Mathews WB, Dannals RF, Gobburu JVS, Peloquin CA, Rower SP, Gumbo T, Ivaturi VD, Jain SK. Dynamic Imaging in Tuberculosis Patients Reveals Heterogeneous Drug Exposures in Pulmonary Lesions. Nature Medicine. 2020. Apr;26(4):529-534.

Ordonez AA, Carroll LS, Abhishek S, Mota F, Ruiz-Bedoya CA, Klunk MH, Singh AK, Freundlich JS, Mease RC, Jain SK. Radiosynthesis and PET Bioimaging of 76Br-Bedaquiline in a Murine Model of Tuberculosis. ACS Infectious Diseases. 2019;5(12),1996-2002.

Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, Kübler A, Bishai WR, Elkington PT, Jain SK. Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology. Journal of Infectious Diseases. 2019;219(4):633-636.

Ordonez AA, Sellmyer MA, Gowrishankar G, Ruiz-Bedoya CA, Tucker EW, Palestro CJ, Hammoud DA, Jain SK. Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation. Science Translational Medicine. 2019 Sep 4;11(508).

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Activities & Honors

Honors

  • Arthur M Dannenberg Jr. Award for excellence in Tuberculosis Research, Johns Hopkins University School of Medicine, 2014
  • A. McGhee Harvey Research Award, Johns Hopkins University School of Medicine, 2017
  • Alavi-Mandell Award, Society of Nuclear Medicine and Molecular Imaging, 2018
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