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Maria L. Golson, Ph.D.

Photo of Dr. Maria L. Golson, Ph.D.
  • Assistant Professor of Medicine

Background

Dr. Maria Golson joined the Division of Endocrinology, Obesity and Metabolism in 2019. Her laboratory is interested in the intrinsic and extrinsic regulators of beta-cell function and insulin secretion.

Dr. Golson received her B.S. in Biology with a concentration in Genetics from Duke University. She then pursued her Ph.D. in Cell and Molecular Biology with a concentration in Genetics and Gene Regulation at the University of Pennsylvania. She completed her postdoctoral training at Vanderbilt University before starting her faculty career as a Research Assistant Professor in the Department of Genetics at the University of Pennsylvania. Throughout her career, Dr. Golson has studied various aspects of pancreatic endocrine cell development and function.

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Titles

  • Assistant Professor of Medicine

Departments / Divisions

Education

Degrees

  • Ph.D., University of Pennsylvania (Pennsylvania) (2008)
  • B.S., Duke University (North Carolina) (2000)

Research & Publications

Selected Publications

Kameswaran, V, Golson M, Rodriguez M, Ou K, Wang YJ, Zhang J, Pasquali L, and Kaestner, K. The dysregulation of the DLK1-MEG3 locus in islets from type 2 diabetics is mimicked by targeted epimutation of its promoter with TALE-DNMT constructs. Diabetes. 2018 Sep; 67(9):1807-1815. Doi: 10.2337/db17-0682. Epub 2018 Jul 3

Wang YJ, Golson ML, Schug J, Traum D, Liu C, Vivek K, Dorrell C, Naji A, Powers AC, Chang KM, Grompe M, and Kaestner KH. Single-Cell Mass Cytometry of the Human Endocrine Pancreas. Cell Metabolism. 2016 Oct: 24(4): 616-626

Wang YJ, Schug J, Won KJ, Liu C, Naji A, Avrahami D, Golson ML, and Kaestner KH. Single-Cell Transcriptomics of the Human Endocrine Pancreas. Diabetes. 2016 Oct;65(10):3028-38. doi: 10.2337/db16-0405. Epub 2016 Jun 30

Golson ML, Dunn J, Dadi PK, Osipovich AB, Magnuson MA, Jacobson DA, and Gannon M. Activation of FoxM1 revitalizes the replicative potential of aged beta-cells in male mice and enhances insulin secretion. Diabetes. 2015 Nov;64(11):3829-38

Golson ML, Maulis MF, Dunn JC, Poffenberger G, Schug J, Kaestner, KH, and Gannon MA. Activated FoxM1 attenuates STZ-mediated beta-cell death. Molecular Endocrinology. 2014 Sep;28(9):1435-47

Contact for Research Inquiries

Lab
5501 Hopkins Bayview Circle
Allergy and Asthma 2A.20
BALTIMORE, MD 21224 map

Activities & Honors

Memberships

  • American Diabetes Association
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