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David Mingdar Wu, M.D., Ph.D.

Photo of Dr. David Mingdar Wu, M.D., Ph.D.
  • Assistant Professor of Ophthalmology


Diabetic Retinopathy, Epiretinal Membranes, Macular Degeneration, Macular Degeneration (Age-Related), Ophthalmology, Retinal Detachment, Vitreoretinal Diseases and Surgery Service more

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Johns Hopkins Wilmer Eye Institute - Bethesda

Appointment Phone: 240-482-1100
6430 Rockledge Drive
Westmoreland Building, Suite 600
Bethesda, MD 20817 map

The Johns Hopkins Hospital

Appointment Phone: 410-955-5080
600 N. Wolfe Street
Wilmer Eye Institute
Baltimore, MD 21287 map
Phone: 410-955-5080


David M. Wu, M.D., Ph.D., is a vitreoretinal surgeon and scientist seeing patients in Baltimore and Bethesda, Maryland. He specializes in diseases of the retina, including retinal detachments, diabetic retinopathy, retinal vascular occlusions, age-related macular degeneration, vitreomacular traction, macular holes, and epiretinal membranes. 

Dr. Wu is an expert in the repair of complex retinal detachments including those secondary to diabetic tractional detachment, proliferative vitreoretinopathy and trauma. Before joining the Wilmer Eye Institute, in 2019 he was on the faculty at Harvard Medical School, where he was a sought after teacher of retinal surgery and named one of Boston’s top doctors. Dr. Wu is one of the few vitreoretinal surgeons with expertise in using cutting-edge molecular technologies to advance research from bench to bedside. more


  • Assistant Professor of Ophthalmology

Departments / Divisions



  • MD, University of Michigan Medical School (2005)


  • University of Michigan Health System / Ophthalmology (2009)


  • University of Michigan Health System (2010)
  • Keck School of Medicine of USC / Vitreoretinal Surgery (2012)

Board Certifications

  • American Board of Ophthalmology / Ophthalmology (2011)

Research & Publications

Research Summary

Dr. Wu’s research technologies include next-generation sequencing and viral vectors to identify and develop new therapies for retinal diseases. He is working to understand the relationship between neighboring layers of the eye — the retinal pigment epithelium and the retina — and how stress in this relationship may lead to damage for people with conditions such as age-related macular degeneration (AMD) and retinal detachment.  

Dr. Wu is a co-inventor of a gene therapy vector that has the potential to treat AMD and retinal degenerations, and he has received funding from the National Institutes of Health/National Eye Institute. He has presented nationally and internationally on retina surgery and retinal laboratory research, and has published multiple research and clinical manuscripts as well as book chapters.


Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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