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Karisa Schreck, M.D., Ph.D.

Karisa Colleen Schreck, M.D., Ph.D.

Photo of Dr. Karisa Schreck, M.D., Ph.D.
  • Assistant Professor of Neurology

Specializes in: Adults (18+ years), Geriatrics (55+ years)



Brain Cancer, Brain Tumors, Gliomas, Meningiomas, Neurology, Targeted/Biologic Therapy

Research Interests

Clinical Trials; Resistance to Small-Molecule Targeted Therapies; Personalized Medicine; Predictive Biomarkers for Treatment.


The Johns Hopkins Hospital

600 N. Wolfe Street
Baltimore, MD 21287 map


Karisa Schreck, assistant professor of neurology, oncology and neurosurgery, is co-director of the BRAF Brain Tumor Center at Johns Hopkins. Her research focuses on the development of small-molecule targeted therapies for patients with primary brain tumors. Dr. Schreck has specific expertise in the treatment of BRAF gene mutations. As such, she works with Christine Pratilas’ laboratory to investigate resistance mechanisms to BRAF-targeted therapy. Dr. Schreck also writes and runs clinical trials for novel targeted agents through the Adult Brain Tumor Consortium and the Alliance for Clinical Trials in Oncology. more


  • Assistant Professor of Neurology
  • Assistant Professor of Neurosurgery
  • Assistant Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD PhD, Johns Hopkins University School of Medicine (2012)


  • Johns Hopkins University School of Medicine / Neurology (2016)


  • Johns Hopkins University School of Medicine / Neuro-Oncology (2019)
  • National Institutes of Health / Neuro-Oncology (2019)

Board Certifications

  • American Board of Psychiatry And Neurology / Neurology (2016)

Research & Publications

Clinical Trial Keywords

BRAF, ketogenic diet,

Clinical Trials

Dr. Schreck conducts clinical trials of small molecule targeted therapies in glioma and other primary brain tumors.

Contact for Research Inquiries

201 N Broadway
Viragh Bldg, Rm. 9179, Box#3
Baltimore, MD 21287 map

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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