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Neeha Zaidi, M.D.

Photo of Dr. Neeha Zaidi, M.D.
  • Assistant Professor of Oncology

Background

Dr. Neeha Zaidi is a physician scientist and a medical oncologist, caring for patients with gastrointestinal malignancies, including pancreatic and colorectal cancer.

Dr. Zaidi received her undergraduate degree (Magna Cum Laude) in Biology from Cornell University and earned her M.D. from the Mount Sinai School of Medicine where she graduated with Distinction in Research. During medical school, she spent a year as a Howard Hughes Medical Institute (HHMI) Research Fellow at The Rockefeller University studying dendritic cell vaccines. She completed her residency in internal medicine at Weill Cornell and subsequently received an Intramural Research Training Award to perform a year-long post-doctoral fellowship at the Vaccine Research Center (NIAID) at the NIH. She then completed a fellowship in medical oncology at the Sidney Simmel Comprehensive Cancer Center at Johns Hopkins. Dr. Zaidi joined the Johns Hopkins faculty in 2019.

Dr. Zaidi’s laboratory focuses on developing novel personalized immunotherapy approaches for the treatment and prevention of pancreatic cancer.

Dr. Zaidi has most recently been recognized with an ASCO Young Investigator Award and a GI SPORE Career Enhancement Award.

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Education

Degrees

  • MD, Mount Sinai School of Medicine (2012)

Residencies

  • New York-Presbyterian/Weill Cornell Med Center / Internal Medicine (2015)

Fellowships

  • Johns Hopkins University School of Medicine / Oncology (2019)

Board Certifications

  • American Board of Internal Medicine / Internal Medicine (2015)
  • Pending/Scheduled / Hematology/Oncology

Research & Publications

Selected Publications

View all on Pubmed

Kinkead HL, Hopkins A, Lutz E, Wu AA, Yarchoan M, Cruz K, Woolman S, Vithayathil T, Glickman LH, Ndubaku CO, McWhirter SM, Dubensky TW Jr, Armstrong TD, Jaffee EM*, Zaidi N*. (2018) Combining STING–based neoantigen–targeted vaccine with checkpoint modulators enhances anti–tumor immunity in murine pancreatic cancer. JCI Insight 3 (20): pii: 122857. PMID: 30333318. [*EMJ and NZ Corresponding Authors].

Zaidi N, Soban M, Chen F, Mathew J, Kinkead, HL, Armstrong TA, Haider S, Jaffee EM (2020) Role of in silico structural modeling in predicting immunogenic neoepitopes for cancer vaccine development. (2020) JCI Insight 5(17): 136911. PMID: 32879142

Zaidi N, Quezada S, Kuroiwa JM, Zhang L, Jaffee EM, Steinman RM, Wang B (2019) Anti-CTLA-4 therapy synergizes with dendritic cell targeting vaccines to promote effector T cell infiltration in an IL-3–dependent manner. Annals of the New York Academy of Sciences 1445: 62-73. PMID: 30954313

Lynn GM, Sedlik C, Baharom F, Zhu Y, Ramirez-Valdez RA, Coble VL, Tobin K, Nichols SR, Itzkowitz Y, Zaidi N, Gammon JM, Blobel NJ, Denizeau J, de la Rochere P, Francica BJ, Decker B, Maciejewski M, Cheung J, Yamane H, Smelkinson MG, Francica JR, Laga R, Bernstock JD, Seymour LW, Drake CG, Jewell CM, Lantz O, Piaggio E, Ishizuka AS, Seder RA. (2020) Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens. Nature Biotechnology 38: 320-332. PMID: 31932728

Sohal DPS, Kennedy EB, Cinar P, Conroy T, Copur MS, Crane CH, Garrido-Laguna I, Lau MW, Johnson T, Krishnamurthi S, Moravek C, O’Reilly EM, Philip PA, Pant S, Shah MA, Sahai V, Uronis HE, Zaidi N, Laheru D. Metastatic Pancreatic Cancer: ASCO Guideline Update. Journal of Clinical Oncology. 2020. PMID: 32755482

Activities & Honors

Honors

  • Young Investigator Award, American Society of Clinical Oncology, 2018
  • Career Enhancement Award, GI SPORE, 2019
  • The Linda Rubin Fellowship in Pancreatic Cancer Research and Patient Care (2nd recipient), Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 2018
  • Inaugural PSTP Scholar, Physician–Scientist Training Program, Johns Hopkins University School of Medicine, 2017
  • Intramural Research Training Award, National Institute of Health, 2015
  • Jeffrey Modell Clinical Immunology Prize, Mount Sinai School of Medicine, 2012
  • Distinction in Research, Mount Sinai School of Medicine, 2015
  • Howard Hughes Medical Research Fellow, HHMI, 2011
  • American Physician–Scientist Association (APSA) Annual Meeting Travel Award, Joint ASCI–AAP–APSA Meeting, 2012
  • Magna Cum Laude, Cornell University, 2007
  • Dean's List, Cornell University, 2005 - 2007
  • Young Invesitagor, Stand Up 2 Cancer, 2017
  • Member of ASCO Expert Panel for Metastatic Pancreatic Cancer Guidelines, American Society of Clinical Oncology, 2018

Memberships

  • American Society of Cancer Oncology

    Member

  • American Association of Cancer Research

    Member

  • American Physician–Scientist Association

    Member

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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