Ahizechukwu C Eke, M.B.Ch.B., Ph.D., M.P.H.

Headshot of Ahizechukwu C Eke
  • Director of Research, Division of Maternal Fetal Medicine
  • Associate Professor of Gynecology and Obstetrics
Male

Languages: English, Igbo

Expertise

Autoimmune Diseases, Cervical Cerclage, Genetic Diseases, High Blood Pressure (Hypertension), High-risk Pregnancy, Lupus, Maternal and Fetal Medicine, Maternal Cardiac and Renal Disease, Medication Use in Pregnancy, Multiple Gestations, Obstetrics, Obstetrics and Gynecology, Preeclampsia, Preterm Birth, Progersterone, Thyroid Disorders ...read more

Research Interests

Preterm birth; Pharmacokinetics; Pharmacodynamics; Pharmacoepidemiology; Pharmacogenomics; Pharmacomicrobiomics; HIV in pregnancy; Maternal Health Policy; Medical and Surgical Complications in Pregnancy ...read more

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Main Phone

Outside of Maryland & Washington D.C.

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Locations

The Johns Hopkins Hospital

Appointment Phone: 443-997-0400
600 N. Wolfe Street
Baltimore, MD 21287
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Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 443-997-0400
10753 Falls Road
Johns Hopkins Women's Center, Pavilion II, Suite 245
Lutherville, MD 21093
Phone: 443-997-0400 | Fax: 410-367-3312
Johns Hopkins Medicine - Green Spring Station - Google Maps

Background

Ahizechukwu C Eke, M.B. ChB., Ph.D., M.P.H., is a specialist in maternal-fetal medicine with areas of clinical and research expertise in medical and surgical complications of pregnancy with a focus on prediction and prevention of preterm birth, pharmacokinetics, pharmacodynamics, pharmacoepidemiology, pharmacogenomics, pharmacomicrobiomics, maternal-fetal medicine, multiple pregnancies, obstetric ultrasound and HIV in pregnancy.

Dr. Eke earned his undergraduate degree from Federal Government College, Wukari, Taraba State, Nigeria, and his medical degree from the College of Medicine, University of Calabar, Nigeria. He completed two obstetrics and gynecology residencies – at the Nnamdi Azikiwe University Teaching Hospital, Nigeria (2005-2010) and at Michigan State University/Sparrow Hospital, which he completed in 2016, and then completed Maternal-Fetal Medicine and Clinical Pharmacology fellowships at the Johns Hopkins University School of Medicine in Baltimore, Maryland in 2019. He earned an MPH from the Harvard University School of Public Health in 2011, and a PhD in Clinical Investigation from the Johns Hopkins University School of Public Health Graduate Training Program in Clinical Investigation (GTPCI) in 2021. He joined the Johns Hopkins faculty in 2019.

Dr. Eke serves on a number of national and international boards and committees. He is a member of Alpha Omega Alpha (AOA), Delta Omega Alpha (DOA), the American College of Obstetrics and Gynecology (ACOG), the American Medical Association (AMA), the American Society for Clinical Investigation (ASCI), the Society of Maternal-Fetal Medicine (SMFM), the American Public Health Association (APHA), the West African College of Surgeons (FWACS), and the Infectious Disease Society of Obstetrics and Gynecology. He currently serves on the Committee on Practice Bulletins (CPG) of ACOG, and is a member of the National Academies of Sciences, Engineering and Medicine (NASEM) committee on 'Developing a framework to address legal, ethical, regulatory, and policy issues for research specific to pregnant and lactating Persons'. Dr. Eke is an editorial board member of Obstetrics and Gynecology (the Green Journal) and the New England Journal of Medicine (NEJM Evidence). He is an active member of NIH study sections.

Dr. Eke has published several articles in obstetrics and maternal-fetal medicine journals, and written numerous textbook chapters. He is a journal reviewer for several peer-reviewed journals in his specialty, including Obstetrics & Gynecology (Green Journal), American Journal of Obstetrics and Gynecology (Gray Journal), and the International Journal of Obstetrics and Gynecology.

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Titles

  • Director of Research, Division of Maternal Fetal Medicine
  • Associate Professor of Gynecology and Obstetrics

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MBChB; University of Calabar (2003)

Residencies

  • Obstetrics and Gynecology; Nnamdi Azikwe University Teaching Hospital (2010)
  • Obstetrics and Gynecology; Sparrow Hospital (2016)

Fellowships

  • Maternal & Fetal Medicine; Johns Hopkins University School of Medicine (2019)

Board Certifications

  • American Board of Obstetrics and Gynecology (OB/GYN-General) (2017)
  • American Board of Obstetrics and Gynecology (OB/GYN-Maternal Fetal Medicine) (2021)

Additional Training

  • MPH:  Harvard T H Chan School of Public Health (2011)
  • PhD: Johns Hopkins Bloomberg School of Public Health (2021)

Research & Publications

Research Summary

Preterm birth, Pharmacokinetics, Pharmacodynamics, Pharmacoepidemiology, Pharmacogenomics, Pharmacomicrobiomics, HIV in pregnancy, Maternal Health Policy, medical and surgical complications in pregnancy. 

Clinical Trial Keywords

Pharmacoepidemiology, Pharmacokinetics, Pharmacodynamics, Pharmacogenomics, Pharmacomicrobiomics, Preterm birth

Selected Publications

View all on PubMed

Eke AC, Dooley KE, Sheffield JS. Pharmacologic Research in Pregnant Women - Time to Get It Right. N Engl J Med. 2019; 380(14):1293-1295.

Eke AC, Mirochnick M, Lockman S. Antiretroviral Therapy and Adverse Pregnancy Outcomes in People Living with HIV. N Engl J Med. 2023; 388(4):344-356.

Bienstock JL, Eke AC, Hueppchen NA. Postpartum Hemorrhage. N Eng J Med. 2021; 384(17):1635-1645.

Eke AC, McCormack SA, Best BM, Stek AM, Wang J, Kreitchmann R, Shapiro D, Smith E, Mofenson LM, Capparelli EV, Mirochnick M; IMPAACT P1026s Protocol Team. Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum. J Clin Pharmacol. 2019; 59(3):386-393.

Eke AC, Chakhtoura N, Kashuba A, Best BM, Sykes C, Wang J, Stek AM, Smith E, Calabrese S, Capparelli EV, Mirochnick M; IMPAACT P1026s Protocol Team. Rilpivirine Plasma and Cervicovaginal Concentrations in Women During Pregnancy and Postpartum. J Acquir Immune Defic Syndr. 2018; 78(3):308-313.

Contact for Research Inquiries

Johns Hopkins Hospital
600 N Wolfe Street
Phipps 228
Baltimore, MD 21287 map

Academic Affiliations & Courses

Graduate Program Affiliation

Director, Maternal-Fetal Medicine Research

Activities & Honors

Honors

  • Distinguished Teaching Society (DTS) of the JHU SOM, Johns Hopkins University School of Medicine, 2021
  • ASCI Young Physician Scientist Award, The American Society for Clinical Investigation (ASCI), 2023
  • American Congress of Obstetricians and Gynecologists (ACOG) Donald Richardson’s Paper Prize National Award, American Congress of Obstetricians and Gynecologists, 2016
  • Inductee, Delta Omega Alpha (DOA) Honor Public Health Society
  • Society for Reproductive Investigation (SRI) Pfizer Presidential Award, Society for Reproductive Investigation, 2019 - 2019
  • American College of Obstetrics & Gynecology (ACOG) Warren Pearse Health Policy Award, American College of Obstetrics & Gynecology, 2019
  • AGOS Presidential Travel Award, The American Gynecological Obstetrical Society (AGOS), 2022
  • Cochrane Kenneth Warren Prize for best high quality methodological review, Cochrane Collaboration, Cochrane Collaboration, 2017
  • Society for Reproductive Investigation (SRI) award for Best New Investigator poster presentation, Society for Reproductive Investigation, 2017
  • Paul Leitman’s Global Health Fellowship Travel Award, Johns Hopkins University School of Medicine, Johns Hopkins University School of Medicine, 2017
  • Michigan State University Outstanding Award for Best Medical Student/Resident Educator, Michigan State University, 2016
  • Michigan State University Outstanding Award for Best Medical Student/Resident Educator, Michigan State University, 2015
  • American Congress of Obstetricians and Gynecologists (ACOG) Junior Fellow Rising Star in Advocacy National Award, American Congress of Obstetricians and Gynecologists, 2015
  • Society for Maternal Fetal Medicine (SMFM) Quilligan Scholar, Society for Maternal Fetal Medicine, 2015
  • Society for Maternal Fetal Medicine (SMFM) Resident Award for Excellence in Obstetrics, Society for Maternal Fetal Medicine, 2015
  • Ephraim McDowell Award for best Junior Fellow research paper in ACOG District V, American College of Obstetrics & Gynecology, 2015
  • National Institute of Health (NIH)/National Medical Association Scholar, National Medical Association, 2015
  • Inductee, Alpha Omega Alpha (AOA) Honor Medical Society, Michigan State University, Alpha Omega Alpha (AOA) Honor Medical Society, 2014
  • American Medical Association (AMA) Foundation National Excellence in Medicine Leadership Award for outstanding leadership skills, American Medical Association, 2014
  • Winning oral presentation, ACOG Junior fellow District V Resident research day, Louisville Kentucky, American College of Obstetricians & Gynecologists, 2013
  • Diversity Minority Fellowship Award, Barnes Jewish Hospital, St Louis, Barnes Jewish Hospital, St Louis, 2012
  • HIVMA travel Scholarship, 2012 to the World’s AIDS Conference, Washington DC., HIVMA, 2012
  • Fellow, West African College of Surgeons (FWACS), 2012
  • Nominated for the Albert Schweitzer Award, the highest accolade for students graduating from the HSPH, Harvard School of Public Health, 2011
  • A.G. Leventis Scholarship Award for Academic Excellence, Harvard School of Public Health, Harvard School of Public Health, 2011
  • Essay winner, Global Forum for Health Research/Lancet International Essay Competition, 2007, Global Forum for Health Research, 2007

Memberships

  • Society for Maternal Fetal Medicine
  • American College of Obstetricians and Gynecologists (ACOG)
  • West African College of Surgeons (WACS)
  • National Postgraduate Medical College of Nigeria
  • Royal College of Obstetricians & Gynecologists
  • Cochrane Collaboration
  • American Public Health Association
  • American Medical Association
  • Nigerian Medical Association
  • International College of Surgeons (ICS)
  • International Leadership Association (ILA)

Professional Activities

  • American College of Obstetricians & Gynecologists (ACOG) Junior Fellow Immediate Past Chair for District IV, American College of Obstetricians and Gynecologists, 10/2018 to 10/2019
  • American College of Obstetricians & Gynecologists (ACOG) Junior Fellow Chair for District IV, American College of Obstetricians and Gynecologists, 10/2017 - 10/2018.
  • American College of Obstetricians & Gynecologists (ACOG) Junior Fellow Vice Chair for District IV, American College of Obstetricians and Gynecologists, 10/2016 - 10/2017
  • American College of Obstetricians & Gynecologists (ACOG) District V Junior Fellow Representative to the American Medical Association (AMA) Residents and Fellows Section (RFS), 10/2015 - 10/2016.
  • American College of Obstetricians & Gynecologists (ACOG) Junior Fellow Secretary/Treasurer for District V, American College of Obstetricians and Gynecologists, 10/2015 - 10/2016
  • American College of Obstetricians & Gynecologists (ACOG) Chair, Junior Fellows, Michigan Section of the American College of Obstetricians and Gynecologists, 10/2014 - 10/2015
  • American College of Obstetricians & Gynecologists (ACOG) Vice Chair, Junior Fellows, Michigan Section of the American College of Obstetricians and Gynecologists, 10/2013 - 10/2014
  • Vice President, Minority Students Association, Harvard School of Public Health, Boston Massachusetts, 9/2010 – 5/2011
  • Peer reviewer, Obstetrics & Gynecology (Green Journal)
  • Peer reviewer, International Journal of Gynecology and Obstetrics (IJGO)
  • Peer reviewer, American Journal of Perinatology (AJP)
  • Peer reviewer, American Journal of Obstetrics & Gynecology (AJOG)
  • Associate Editor, Journal of Maternal Health Neonatology and Perinatology
  • Diplomate, American Board of Clinical Pharmacology, 2020
  • Fellow, West African College of Surgeons, 2012
  • Fellow, American College of Obstetricians & Gynecologists (ACOG), 2017

Videos & Media

Recent News Articles and Media Coverage

Winning the 2017 Kenneth Warren Prize, Cochrane Collaboration (February 22, 2018)

Pharmacologic research in pregnant women – Time to get it right, Global News (April 21, 2019) 

Examining adverse pregnancy outcomes in people living with HIV, Managed Healthcare Executive (Mar 21, 2023)

New study affirms link between sickle cell disease and risk of increased mortality in pregnant people, NewsWise  (Feb 2, 2023)

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