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Yumin Oh, Ph.D.

Photo of Dr. Yumin Oh, Ph.D.
  • Instructor of Radiology and Radiological Science

Research Interests

Role of TRAIL signaling in fibrosis and cancer

Background

Titles

  • Instructor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • Ph.D., Seoul National University (Korea) (2012)
  • B.S., Ajou University (South Korea) (2004)

Research & Publications

Selected Publications

View all on Pubmed

Lee H, Oh Y, Jeon YJ, Lee SY, Kim H, Lee HJ, Jung YK. DR4-Ser424 O-GlcNAcylation promotes sensitization of TRAIL-tolerant persisters and TRAIL-resistant cancer cells to death, Cancer Research, 2019

Park JS*, Oh Y*, Park YJ , Park O , Yang H , Slania S , Hummers L, Shah A, An HT, Jang J, Horton M , Shin J, Dietz H, Song E, Na DH, Park EJ, Kim K, Lee KC, Roschke V, Hanes J , Pomper MG, Lee S, Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma. Nature Communications, 2019 Mar 8;10(1):1128

Yun SP*, Kam TI,* Panicker N, Kim S, Oh Y, Park JS, Kwon SW, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke VV, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S#, Dawson TM#, Ko HS#. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease. Nature Medicine, 2018 Jul;24(7):931-938

OhY,* ParkO,* Swierczewska M,* Hamilton JO, ParkJS, KimTH, LimSM, EomH, Jo DG, Lee CE,Kechrid R, Mastorakos P, ZhangC, Hahn SK, Jeon OC, Byun R, KiK, Hanes J, Lee KC, PomperMG,Gao B, Lee S, Systemic TRAIL treatmentameliorates livercirrhosis in rats byeliminatingactivatedhepatic stellate cells. Hepatology, 2016 Jul;64(1):209-23

Oh Y,* Swierczewska M,* Kim TH, Lim SM, Eom HN, Park JH, Na DH, Kim K, Lee KC, Pomper MG,Lee S, Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistanttumors. Journal of Controlled Release, 2015 Dec 28;220(PtB):671-81

Activities & Honors

Honors

  • Peer Reviewed Cancer Research Program, Career Development Award – Nested Postdoctoral Fellowship, DOD, 2014 - 2017
  • Scholar in Training Award, American Association for Cancer Research, 2015
  • Travel grant recipient, Association for Research in Vision and Ophthalmology, 2017
  • Postdoctoral Fellowship, National Research Foundation, Korea, 2012 - 2013
  • Fellowship, National Research Foundation, Korea, 2016 - 2017
  • Best Research Award, Korea Society for Biochemistry and Molecular Biology, 2012
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