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Mark Yarchoan, M.D.

Photo of Dr. Mark Yarchoan, M.D.
  • Assistant Professor of Oncology

Expertise

Cholangiocarcinoma, Gastrointestinal Cancers, Hepatobiliary Malignancies, Hepatocellular Cancer, Liver Cancer

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Insurance Information

Maryland

410-955-8964

Outside of Maryland

410-464-6641
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International Patients

+1-410-502-7683
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Locations

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Appointment Phone: 410-955-8964
401 N. Broadway
Baltimore, MD 21231 map
Phone: 410-955-8974

The Bunting Blaustein Cancer Research Building

1650 Orleans Street
Baltimore, MD 21287 map

Background

Dr. Mark Yarchoan is an oncologist in Baltimore, caring for patients with gastrointestinal cancers.

Dr. Yarchoan received his undergraduate degree (cum laude) in neuroscience from Amherst College and earned his M.D. from the Perelman School of Medicine at the University of Pennsylvania. He completed his residency in internal medicine at the Hospital of the University of Pennsylvania and performed a fellowship in medical oncology at Johns Hopkins University School of Medicine. Dr. Yarchoan joined the Johns Hopkins faculty in 2018.

His research interests include cancer immunotherapy.

Dr. Yarchoan serves on the editorial board of the Cureus Journal of Medical Science. He has been recognized with a Director’s Teaching Award in Clinical Science.

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Education

Degrees

  • MD, University of Pennsylvania School of Medicine (2012)

Residencies

  • Hospital of the University of Pennsylvania / Internal Medicine (2015)

Fellowships

  • Johns Hopkins University School of Medicine / Medical Oncology (2018)

Board Certifications

  • American Board of Internal Medicine / Internal Medicine (2015)
  • American Board of Internal Medicine / Medical Oncology (2017)

Research & Publications

Clinical Trial Keywords

Hepatocellular Carcinoma (HCC), Cholangiocarcinoma, Liver Cancer, Immunotherapy

Clinical Trials

GVAX Pancreas Vaccine (With CY) in Combination With Nivolumab and SBRT for Patients With Borderline Resectable Pancreatic Cancer Pancreatic Cancer

DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma Fibrolamellar Hepatocellular Carcinoma (FLC)

Selected Publications

Leaf RK, Ferreri C, Rangachari D, Mier J, Witteles W, Ansstas G, Anagnostou T, Zubiri L, Piotrowska Z, Oo TH, Iberri D, Yarchoan M, Salama AKS, Johnson DB, Leavitt AD, Rahma OE, Reynolds KL, Leaf DE. "Clinical and laboratory features of autoimmune hemolytic anemia associated with immune checkpoint inhibitors." Am J Hematol. 2019 May;94(5):563-574. doi: 10.1002/ajh.25448. Epub 2019 Mar 13.

Yarchoan M, Albacker LA, Hopkins AC, Montesion M, Murugesan K, Vithayathil TT, Zaidi N, Azad NS, Laheru DA, Frampton GM, Jaffee EM. "PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers." JCI Insight. 2019 Mar 21;4(6). pii: 126908. doi: 10.1172/jci.insight.126908. eCollection 2019 Mar 21.

Danilova L, Ho WJ, Zhu Q, Vithayathil T, De Jesus-Acosta A, Azad NS, Laheru DA, Fertig EJ, Anders R, Jaffee EM, Yarchoan M. "Programmed cell death ligand-1 (PD-L1) and CD8 expression profiling identify an immunologic subtype of pancreatic ductal adenocarcinomas with favorable survival." Cancer Immunol Res. 2019 Jun;7(6):886-895. doi: 10.1158/2326-6066.CIR-18-0822. Epub 2019 May 1.

Balaji A, Zhang J, Wills B, Marrone KA, Elmariah H, Yarchoan M, Zimmerman JW, Hajjir K, Venkatraman D, Armstrong DK, Laheru DA, Mehra R, Ho WJ, Reuss JE, Heng J, Vellanki P, Donehower RC, Holdhoff M, Naidoo J. "Immune-related adverse events requiring hospitalization: spectrum of toxicity, treatment, and outcomes." J Oncol Pract. 2019 Sep;15(9):e825-e834. doi: 10.1200/JOP.18.00703. Epub 2019 Aug 6.

Leaf RK, Ferreri C, Rangachari D, Mier J, Witteles W, Ansstas G, Anagnostou T, Zubiri L, Piotrowska Z, Oo TH, Iberri D, Yarchoan M, Salama AKS, Johnson DB, Leavitt AD, Rahma OE, Reynolds KL, Leaf DE. "Clinical and laboratory features of autoimmune hemolytic anemia associated with immune checkpoint inhibitors." Am J Hematol. 2019 May;94(5):563-574. doi: 10.1002/ajh.25448. Epub 2019 Mar 13.

Activities & Honors

Honors

  • Director’s Teaching Award in Clinical Science, 2019
  • Incyte Young Investigator Award for Translational Science, 2019
  • Young Investigator Award, American Society for Clinical Oncology, 2017
  • ASCO Young Investigator Award, Conquer Cancer Foundation, 2017
  • Inaugural Linda Rubin Fellowship Recipient, Johns Hopkins, 2017
  • Selected Participant, American Association for Cancer Research/American Society for Clinical Oncology Workshop Methods in Clinical Cancer Research, 2016
  • Maurice F. Attie Senior Resident Teaching Award, Hospital of the University of Pennsylvania, 2015
  • Maurice F. Attie Junior Resident Teaching Award, Hospital of the University of Pennsylvania, 2014
  • Honorable Mention, Frederick F. Samaha Award for Resident Scholarship, University of Pennsylvania, 2014
  • Sarle H. Cohen Award for Geriatric Medicine, University of Pennsylvania, 2012
  • Medical Student Achievement Award, Endocrine Society, 2010

Professional Activities

  • Editorial Board, Cureus Journal of Medical Science, 2016

Videos & Media

Lectures and Presentations

  • Liver Cancer Provocative Questions
    Keynote Speaker, Baltimore, MD (05/09/2019)
    Johns Hopkins
  • Updates in Hepatocellular Carcinoma (HCC)
    Lecture, Chinese Executive Oncologist Education Program, Baltimore, MD (07/30/2018)
    Johns Hopkins
  • Overview of Cancer Immunotherapy
    Lecture, Johns Hopkins Internal Medicine Residency Housestaff Lecture Series (02/13/2017)
  • Chest Advanced Clinical Training Program
    Lecture, Baltimore, MD (11/29/2016)
    Johns Hopkins
  • Morbidity and Mortality Grand Rounds
    Lecture, Baltimore, MD (11/11/2016)
    Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
  • Introduction to Solid Tumors
    Lecture, Johns Hopkins Internal Medicine Residency, House Staff Noon Lecture Series (10/17/2016)

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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