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Rena Ruiyu Xian, M.D., M.S.

Photo of Dr. Rena Ruiyu Xian, M.D., M.S.
  • Assistant Professor of Pathology

Languages: English, Mandarin


Dr. Rena Xian is an assistant professor of Pathology and Oncology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include diagnostic hematopathology and molecular pathology. Dr. Xian has developed numerous molecular assays, and is an expert in clinical next-generation sequencing. 

Her research focuses on genetic alterations of hematologic malignancies, particularly B-cell neoplasms, non-invasive disease biomarkers, and telomerase regulation. Dr. Xian is interested in the application of large-scale genomics and novel molecular techniques to cancer diagnosis, prognosis and therapeutics. 

Dr. Xian is also passionate about medical education, and the training of genetically-informed physicians. She is active in several professional societies, including the Association for Molecular Pathology, the College of American Pathologists, the Society for Hematopathology, and the American Society of Hematology. 

Prior to joining Johns Hopkins, Dr. Xian was an assistant professor of Pathology and Lab Medicine at University of California, Los Angeles. more


  • Assistant Professor of Pathology
  • Assistant Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD, Northwestern University Feinberg School of Medicine (2009)


  • Hospital of the University of Pennsylvania / Anatomic and Clinical Pathology (2013)


  • Johns Hopkins University School of Medicine / Hematopathology (2014)
  • David Geffen School of Medicine at UCLA (2015)

Board Certifications

  • American Board of Pathology / Anatomic & Clinical Pathology (2013)
  • American Board of Pathology / Hematology (2014)
  • American Board of Pathology / Molecular Genetic Pathology (2015)

Research & Publications

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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