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Matthew Michael Ladra, M.D., M.P.H.

Photo of Dr. Matthew Michael Ladra, M.D., M.P.H.

Director, Pediatric Radiation Oncology, Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital

Assistant Professor of Radiation Oncology and Molecular Radiation Sciences


Expertise: Acute Lymphoblastic Leukemia (ALL), Head and Neck Cancers, Leukemia, Pediatric Radiation Oncology, Primary central nervous system (CNS) lymphoma, Rhabdomyosarcoma, Soft Tissue Sarcoma, Spine Tumors more

Research Interests: Pediatric Rhabdomyosarcoma; Proton Therapy

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Sibley Memorial Hospital


5255 Loughboro Road NW Washington, DC 20016 map

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

401 N. Broadway Weinberg Suite 1440 Baltimore, MD 21231 map

Phone: 410-614-1642


Matthew M. Ladra, M.D., M.P.H., is the director of the pediatric radiation oncology program for the Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital, a clinical collaboration between Children’s National Medical Center, the Johns Hopkins Sidney Kimmel Cancer Center and Sibley Memorial Hospital that provides the highest level of multidisciplinary care for the region’s pediatric oncology patients. Dr. Ladra also serves as an assistant professor in the Department of Radiation Oncology and Molecular Radiation Sciences at Johns Hopkins University School of Medicine. He is board certified in radiation oncology by the American Board of Radiology.

Dr. Ladra has expertise in pediatric radiation clinical care and research, in addition to proton therapy. His clinical interests include pediatric tumors, tumors of the central nervous system and spine, head and neck malignancies, and soft tissue sarcomas. 

Dr. Ladra earned both his medical degree and Masters in Public Health at Tulane University. He completed a residency in radiation oncology at the University of Washington Medical Center, followed by a fellowship in pediatric proton therapy at Massachusetts General Hospital. Dr. Ladra also completed a year-long research fellowship in conjunction with St. Jude Children's Research Hospital, studying and treating pediatric leukemia in Morocco. He trained doctors and data managers to use the Pediatric Online Networked Database, developed by St. Jude, to allow low-income countries to store pediatric oncology patient data and outcomes in a secure, online environment that can be shared with other countries and institutions. 

Dr. Ladra currently serves as a radiation oncology faculty consultant for Children's National Medical Center, a member of the Children's Oncology Group Renal Tumors Committee and a co-organizer for the International Society of Pediatric Oncology's Radiation Oncology Session. He previously served as the director of pediatric radiation oncology at the Provision Center for Proton Therapy—the only proton center open in Tennessee, and along with the University of Florida Proton Institute, one of only two centers treating pediatric patients in the Southeast.

Dr. Ladra is a member of the Children's Oncology Group, the American Society for Therapeutic Radiology and Oncology, and the American College of Radiology. 

Dr. Ladra has been a guest lecturer on pediatric radiation oncology and has contributed to numerous papers, book chapters and international presentations. His research interests focus on pediatric rhabdomyosarcoma and proton therapy. more


  • Director, Pediatric Radiation Oncology, Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital
  • Assistant Professor of Radiation Oncology and Molecular Radiation Sciences

Departments / Divisions



  • MD, Tulane University School of Medicine (2007)


  • University of Washington Medical Center / Radiation Oncology (2012)


  • Massachusetts General Hospital / Radiation Oncology (2014)

Research & Publications

Clinical Trials

View Dr. Ladra's clinical trials at the Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital. 

Selected Publications

Rao AD, Chen Q, Ermoian RP, Alcorn SR, Figueiredo MLS, Chen MJ, Dieckmann K, MacDonald SM, Ladra MM, Kobyzeva D, Nechesnyuk AV, Nilsson K, Ford EC, Winey BA, Villar RC, Terezakis SA. "Practice patterns of palliative radiation therapy in pediatric oncology patients in an international pediatric research consortium." Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26589. Epub 2017 Jul 11.

Shen CJ, Hu C, Ladra MM, Narang AK, Pollack CE, Terezakis SA. "Socioeconomic factors affect the selection of proton radiation therapy for children." Cancer. 2017 Oct 15;123(20):4048-4056. doi: 10.1002/cncr.30849. Epub 2017 Jun 27.

Ladra MM, Wang KK, Terezakis SA. "Pencil-beam scanning for pediatric rhabdomyosarcoma: Promise and precautions." Pediatr Blood Cancer. 2016 Oct;63(10):1698-9. doi: 10.1002/pbc.26103. Epub 2016 Jun 14.

Ladra MM, Mandeville HC, Niemierko A, Padera TP, Friedmann AM, MacDonald SM, Ebb D, Chen YL, Tarbell NJ, Yock TI. "Local failure in parameningeal rhabdomyosarcoma correlates with poor response to induction chemotherapy." Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):358-67. doi: 10.1016/j.ijrobp.2015.01.049. Epub 2015 Apr 8.

Lucas JT Jr, Ladra MM, MacDonald SM, Busse PM, Friedmann AM, Ebb DH, Marcus KJ, Tarbell NJ, Yock TI. "Proton therapy for pediatric and adolescent esthesioneuroblastoma." Pediatr Blood Cancer. 2015 Sep;62(9):1523-8. doi: 10.1002/pbc.25494. Epub 2015 Mar 27.

Activities & Honors


  • Children's Oncology Group


  • American Society for Therapeutic Radiology and Oncology


  • American College of Radiology


Videos & Media

Recent News Articles and Media Coverage

"Washingtonian's 40 Under 40." Washingtonian Magazine. (04/05/2017)

"Matthew Ladra to Head New Johns Hopkins and Children's National Health System Pediatric Radiation Oncology Program at Sibley Memorial Hospital." Johns Hopkins Medicine. (08/30/2016)

"Sibley Memorial Hospital, Children's National announce key hire for proton therapy." Washington Business Journal. (08/30/2016)

"Proton Therapy in East Tennessee: A Healing Environment." Medical Tourism Magazine. (10/13/2015)

"Gray 9-year-old becomes state's first pediatric patient for proton therapy." Johnson City Press. (12/17/2014)

"First child treated at Provision proton therapy center." Knoxville News Sentinel. (11/26/2014)

"Dr. Ladra Speaks About Proton Therapy for Pediatric Cancer Patients." Provision Healthcare. (09/24/2014)

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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