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Jonathan Agner Forsberg, M.D., Ph.D.
Expertise: Bone Sarcoma, Chondrosarcoma, Ewing's Sarcoma, Metastatic Bone Disease, Musculoskeletal Tumors Involving the Extremities, Orthopaedic Surgery, Osseointegration Amputation Surgery, Osteosarcoma, Soft Tissue Sarcoma ...read more
Research Interests: Precision Medicine; Orthopaedic Oncology; Machine Learning; Osseointegration; Heterotopic Ossification; Clinical Bioinformatics
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Sibley Memorial Hospital
Appointment Phone: 202-660-7511
5255 Loughboro Road NW
Washington, DC 20016 map
The Johns Hopkins Hospital
600 N. Wolfe Street
Baltimore, MD 21287 map
Jonathan A. Forsberg, M.D., is an orthopaedic oncologist at Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital and an adjunct associate professor of orthopaedic surgery at Johns Hopkins University School of Medicine. Dr. Forsberg is board certified in orthopaedic surgery by the American Board of Orthopaedic Surgery.
Dr. Forsberg specializes in the treatment of children and adults with bone and soft tissue sarcomas, a rare group of cancers, including osteosarcoma and Ewing's sarcoma. In addition, Dr. Forsberg has considerable expertise in the management of metastatic bone disease and metabolic bone disease, as well as blast- and other combat-related wounds, and limb-sparing surgery. He developed the first validated model to help guide surgical treatment of metastatic bone disease and has completed research to further the understanding of soft tissue sarcomas of the extremities.
Dr. Forsberg earned his medical degree from the F. Edward Hebert School of Medicine. He completed a residency in orthopaedic surgery at the National Naval Medical Center, followed by a fellowship in orthopaedic oncology at the Memorial Sloan-Kettering Cancer Center. Dr. Forsberg also earned a Ph.D. in clinical bioinformatics at Karolinska University in Stockholm, Sweden.
Dr. Forsberg is an active researcher and principle investigator focusing on applying precision medicine to oncologic surgery by using machine-learning approaches, preventing combat-related heterotopic ossification and developing next-generation osseointegration techniques for patients with amputations. He is a regular contributor and previous guest editor for Clinical Orthopaedics and Related Research, the specialty's premier peer-reviewed journal, and previously served as a guest editor for the Journal of Surgical Orthopaedic Advances as well.
Besides seeing patients and conducting research at Johns Hopkins, Dr. Forsberg is also affiliated with several other institutions. He holds appointments at the Murtha Cancer Center at the Walter Reed National Military Medical Center and the National Institutes of Health; is the director of the Department of Defense Osseointegration Program; a professor of surgery at the F. Edward Helbert School of Medicine; and a United States Navy Commander. He has received the Team Award for Distinguished Service by the Defense Health Agency, as well as the Ellis Island Medal of Honor by the National Ethnic Coalition of Organizations. Dr. Forsberg previously served as a medical officer in the 31st Marine Expeditionary Unit in Okinawa, Japan; the director of orthopaedic research in the Department of Regenerative Medicine at the Naval Medical Research Center; and deputy director of the Surgical Critical Care Initiative.
Dr. Forsberg is a fellow of the American Academy of Orthopaedic Surgeons and a member of the Musculoskeletal Tumor Society, the Orthopaedic Surgery Osseointegration Society, the Orthopaedic Research Society, the Association of Bone and Joint Surgeons and the American Orthopaedic Association.
Departments / Divisions
- Orthopaedic Surgery
- Surgery at Sibley Memorial Hospital
- MD, Uniformed Services University of the Health Sciences (2001)
- National Naval Medical Center / Orthopaedic Surgery (2007)
- Memorial Sloan-Kettering Cancer Center (2011)
- American Board of Orthopaedic Surgery / Orthopaedic Surgery (2009)
Research & Publications
Dr. Forsberg is the principle investigator on numerous clinical research protocols, including an international cancer registry and two FDA-regulated clinical trials. His research is focused on applying precision medicine to oncologic surgery by using machine-learning approaches and developing next-generation osseointegration techniques for patients with amputations.
- Improving a Bayesian Model's Survival Estimates in Patients Needing Surgery for Bone Metastases
- Transhumeral Amputation Osseointegration Study (TAOS), an FDA Early Feasibility Study
- Transfemoral Amputation Osseointegration Study (TFAOS)
Selected PublicationsView all on Pubmed
Davis EL Sonnet C, Lazard ZW, Henslee G, Gugala Z, Salisbury EA, Strecker EV, Davis TA, Forsberg JA, Davis AR, *Olmsted-Davis EA, Location-dependent heterotopic ossification in the rat model: The role of activated matrix metalloproteinase, J Orthop Res. 2016 March.
Pavey GJ, Qureshi AT, Tomasino AM, Honnold CL, Bishop DK, Agarwal S, Loder S, Levi B, Pacifici M, Iwamoto M, Potter BK, *Davis TA, Forsberg JA, Targeted stimulation of retinoic acid receptor-γ mitigates the formation of heterotopic ossification in an established blast-related traumatic injury model. Bone. 2016 Jun 28;90:159-167.
Forsberg JA, Potter BK, Wagner MB, Vickers A, Dente CJ, Kirk AD, *Elster EA. Lessons of war: Turning data into decisions, EBioMedicine. 2015 Jul 17;2(9):1235-42.
Forsberg JA, Brown TS, Potter BK, Basic Science of War Wounds. In Owens BD, Belmont P Jr. ed. Combat Orthopedic Surgery: Lessons Learned in Iraq and Afghanistan (2011) 83-90.
Forsberg JA, Editorial: Orthopaedic research after a decade of war. Clin Orthop Relat Res. 2015 Sep;473(9):2769-70.
Method for the analysis of progression of heterotopic ossification by Raman Spectroscopy
Patent # US 20150182119 A1 | 07/02/2015
Analysis is by determination of a number of Raman spectral parameters including the area under one or more of the vibrational bands, band area ratios, band height, ratios of band heights and shift in band center.
Bayesian clinical decision model for determining probability of transplant glomerulopathy
Patent # US 8510245 B2 | 08/13/2013
An embodiment of the invention provides a method for determining a patient-specific probability of transplant glomerulopathy.
Bayesian Clinical Decision Model for Determining Patient Specific Probability of Malignancy in a Thyroid Nodule
Patent # US11/0295782 | 01/01/2009
Bayesian Clinical Decision Model for Determining Patient Specific Probability of Impaired Wound Healing
Patent # US 09/60850 | 01/01/2009
Activities & Honors
- Distinguished Service, Team Award, Defense Health Agency, 2014
- Ellis Island Medal of Honor, National Ethnic Coalition of Organizations
- Musculoskeletal Tumor Society (MSTS), 2010
- Orthopaedic Surgery Osseointegration Society (OSOS), 2010
- Orthopaedic Research Society (ORS), 2013
- American Academy of Orthopaedic Surgeons (AAOS), 2013
- Association of Bone and Joint Surgeons (ABJS), 2015
- Guest Editor, Journal of Surgical Orthopaedic Advances, 2011
- Guest Editor, Clinical Orthopaedics and Related Research, 2015
Videos & Media
Lectures and Presentations
Heterotopic Ossification in Combat Wounds
oral presentation, Houston TX (09/14/2014)
American Society of Bone and Mineral Research
The PATHFx project: Decision analysis and Bayesian estimation of survival
oral presentation, Update on Bone Metastases, Rome Italy (04/15/2016)
Combat Related Amputations
oral presentation, Orthopaedic Grand Rounds, Stockholm, Sweden (09/12/2012)
Karolinska University Hospital
Recent News Articles and Media Coverage
Osseointegration Offers Amputees a Revolutionary New Option in Prosthesis, Naval Medical Research and Development (June 2017)
Military Medicine Provides 'World-Class Solutions for Combat Casualties,' The Military Health System and the Defense Health Agency (January 2017)
A Day in Life of an Orthopaedic Oncologist and Navy Commander Jonathan Forsberg, Medicine + the Military (September 2015)
Researchers Identify Model to Predict Successful Wound Healing, Science Daily (July 2015)
Soldier Blown Apart by War Stages Stirring Comeback, USA Today (December 2013)