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Abhinav Kumar Jha, M.S., Ph.D.

Photo of Dr. Abhinav Kumar Jha, M.S., Ph.D.

Instructor of Radiology and Radiological Science


Dr. Abhinav K. Jha is an Instructor in the Division of Medical Imaging Physics, Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine. 

Dr. Jha obtained his PhD from the College of Optical Sciences, University of Arizona. He was the valedictorian of his graduating batch. In his PhD, Dr. Jha developed novel tools to retrieve clinically relevant information from scattered photons in diffuse optical imaging and gamma-ray imaging.

Dr. Jha’s research is based on the theme that medical images are acquired for a certain clinical task. Thus, the design, optimization, and evaluation of medical imaging systems and methods should be based on the performance in the clinical task. His research includes devising novel tools for quantitative imaging, objective evaluation of image quality, simulating imaging systems, designing image reconstruction methods and image-analysis tools, and the use of high-performance computing in medical imaging.

A major theme of his current research is in improving the application of quantitative imaging in the clinic. Current projects are in developing methods for improved quantitation of clinically relevant quantitative parameters (both in nuclear medicine and diffusion MRI), designing improved imaging systems and optimized protocols for quantitative imaging, and finally, designing frameworks for evaluating these systems and methods with patient data (no-gold-standard evaluation). While most projects are on applications in oncology, there are also projects on transcranial and myocardial imaging. 

Dr. Jha has been given several awards for his research, including those from ECOG-ACRIN, Society of Nuclear Medicine and Molecular Imaging, and SPIE Medical Imaging societies. more


  • Instructor of Radiology and Radiological Science



  • B.Tech., Motilal Nehru National Institute of Technology Allahabad (India) (2005)
  • M.S., University of Arizona (Arizona) (2009)
  • Ph.D., University of Arizona (Arizona) (2013)

Research & Publications

Selected Publications

View all on Pubmed

A. K. Jha, E. Mena, B. Caffo, S. Ashrafinia, A. Rahmim, E. C. Frey and R. Subramaniam, "A practical no-gold-standard evaluation framework for quantitative imaging methods: Application to lesion segmentation in PET", J. Med. Imag. (special section on PET imaging), 2017

A. K. Jha, J. J. Rodriguez and A. T. Stopeck, "A maximum-likelihood method to estimate a single ADC value of lesions using diffusion MRI, Mag Res Med, 76 (6), 1919-31, 2016

A. K. Jha, B. Caffo, and E. Frey, "Developing and investigating the performance of a no-gold-standard technique for objective assessment of quantitative nuclear-medicine imaging methods", Phys. Med. Biol., 61(7); 2016

A. K. Jha, H. H. Barrett, E. Frey, E. Clarkson, L. Caucci, and M. A. Kupinski, "Singular value decomposition for photon-processing nuclear imaging systems and applications for reconstruction and computing null functions", Phys. Med. Biol., 60 (2015) 7359-7385

A. K. Jha, E. Clarkson, and M. A. Kupinski, "An ideal-observer framework to investigate signal detectability in diffuse optical imaging", Biomed. Opt. Express, 4(10), 2107-23, 2013

Activities & Honors


  • Valedictorian, College of Optical Sciences, University of Arizona, 2013
  • Young Investigator Symposium Award of Distinction for Translational Sciences, ECOG-ACRIN Fall Meeting, 2015
  • Bradley Alavi Fellowship, Society of Nuclear Medicine and Molecular Imaging, 2012
  • William Wolfe Family Endowed Scholarship, College of Optical Sciences, University of Arizona, 2011
  • Technology Research Initiative Fund Imaging Fellowship, University of Arizona
  • Michael B. Merickel Best Student Paper Award, SPIE, 2010
  • KVPY - National Science Fellow of the Indian Institute of Science (IISc), Bangalore, Department of Science and Technology, Govt. of India
  • Rolyn Optics Outstanding Graduate Student Teaching Assistant Award, University of Arizona
  • Young Investigator Award, Therapy Center for Excellence SNMMI, 2017


  • IEEE

Professional Activities

  • Reviewer, 2009
    Reviewer for IEEE Transactions on Medical Imaging, Optics Express, Medical Physics, IEEE Transactions on Nuclear Science, Applied Optics, Journal of Medical Imaging, Multidimensional Systems and Signal Processing, and the IEEE Medical Imaging conference

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