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Reza Sedighi Manesh, M.D.

Photo of Dr. Reza Sedighi Manesh, M.D.

Assistant Professor of Medicine


Languages: English, Farsi

Research Interests: Diagnostic expertise; Clinical reasoning; Effective teaching


The Johns Hopkins Hospital

600 N. Wolfe Street
Nelson/Harvey Building, Suite 215
Baltimore, MD 21287 map

Contact for Research Inquiries

The Johns Hopkins Hospital
600 N. Wolfe Street
Nelson 215
Baltimore, MD 21287 map


Dr. Reza Sedighi Manesh is an assistant professor of medicine at the Johns Hopkins University School of Medicine. As a clinician-educator, he is passionate about patient care and the teaching of both graduate and undergraduate medical trainees. His academic interests include the study and teaching of clinical reasoning and diagnostic expertise. more


  • Assistant Professor of Medicine

Departments / Divisions



  • MD, University of Pittsburgh School of Medicine (2012)


  • University of California San Francisco School of Medicine / Internal Medicine (2015)

Board Certifications

  • American Board of Internal Medicine / Internal Medicine (2015)

Additional Training

  • American Board of Internal Medicine/Internal Medicine (2015)

Research & Publications

Selected Publications

View all on Pubmed

Mixter S, Manesh RS, Keller SC, Platt L, Hollander H. Spiraling Out of Control. N Engl J Med. 2017 Jun 1;376(22):2183-8

Sethi N, Sedighi Manesh R, Sperling A, Bresler SC, Connell NT, Tierney LM. Factoring in the missing link. Am J Hematol. 2017 Jan 1;92(1):110-3

Anderson ME, DeNiro KL, Harte BJ, Sedighi Manesh R. The missing element. J Hosp Med. 2016 Dec;11(12):879-882

Bailey CR, Ray-Mazumder N, Manesh RS. Carotid Cavernous Fistula. J Gen Intern Med. 2016 Sep 9:1-2

Martin M, Sedighi Manesh R, Henderson MC, Critchfield JM. Diagnostic Scheming. J Gen Intern Med. 2015 Dec;30(12):1874-8

Activities & Honors


  • Jeremiah A. Barondess Fellowship in the Clinical Transaction of The New York Academy of Medicine, 2017
  • Osler Housestaff Full-Time Faculty Teaching Award, Johns Hopkins, 2016
  • The Jeffrey Weingarten Award, UCSF, 2015
  • The Elizabeth Safar Memorial Award for Providing Compassionate Care, University of Pittsburgh, 2012
  • Mayar A. Green, M.D. Student Award for Academic Achievement and Human Qualities, University of Pittsburgh, 2012
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