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Reza Sedighi Manesh, M.D.

Photo of Dr. Reza Sedighi Manesh, M.D.
  • Assistant Program Director for Clinical Reasoning, Osler Medical Training Program
  • Assistant Professor of Medicine

Languages: English, Farsi

Research Interests

Diagnostic expertise; Clinical reasoning


The Johns Hopkins Hospital

600 N. Wolfe Street
Nelson/Harvey Building, Suite 215
Baltimore, MD 21287 map


Dr. Reza Manesh is an Assistant Professor of Medicine at the Johns Hopkins University School of Medicine. He is the Assistant Program Director for Clinical Reasoning of the Osler Medical Training Program. He is the co-founder and host of the Clinical Problem Solvers – a podcast dedicated to diagnostic medicine. His academic interests include the study and teaching of clinical reasoning and diagnostic expertise to both undergraduate and graduate medical trainees. more


  • Assistant Program Director for Clinical Reasoning, Osler Medical Training Program
  • Assistant Professor of Medicine

Departments / Divisions



  • MD, University of Pittsburgh School of Medicine (2012)


  • University of California San Francisco School of Medicine / Internal Medicine (2015)

Board Certifications

  • American Board of Internal Medicine / Internal Medicine (2015)

Additional Training

  • American Board of Internal Medicine/Internal Medicine (2015)

Research & Publications

Selected Publications

View all on Pubmed

Geha RM, Dhaliwal G, Winston LG, Kickler TS, Manesh R. Overcoming the Barrier. N Engl J. 2018 Dec 6;379(23):2256-61.

Atri D, Furfaro D, Dhaliwal G, Feingold KR, Manesh R. Going from A to Z. N Engl J Med. 2018 Jan 4;378(1):73-79

Handy Marshall C., Nahas-Vigon J., Manesh R., Gelber A.C. 2018. Just Beneath the Surface. N Engl J Med, 379(10), pp.968-973.

Manesh R. Mistakes Were Made (by Me). JAMA Intern Med. 2017 Oct 1;177(10):1422-1423

Mixter S, Manesh R, Keller SC, Platt L, Hollander H. Spiraling Out of Control. N Engl J Med. 2017 Jun 1;376(22):2183-8

Contact for Research Inquiries

The Johns Hopkins Hospital
600 N. Wolfe Street
Nelson 215
Baltimore, MD 21287 map

Activities & Honors


  • Faculty Marshal at the School of Medicine Convocation, Class of 2019
  • Inducted into the Distinguished Teaching Society of Johns Hopkins University School of Medicine, 2019
  • Jeremiah A. Barondess Fellowship in the Clinical Transaction of The New York Academy of Medicine, 2017
  • Osler Housestaff Full-Time Faculty Teaching Award, Johns Hopkins, 2016
  • The Jeffrey Weingarten Award, UCSF, 2015
  • The Elizabeth Safar Memorial Award for Providing Compassionate Care, University of Pittsburgh, 2012
  • Mayar A. Green, M.D. Student Award for Academic Achievement and Human Qualities, University of Pittsburgh, 2012

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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