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Nicole Schmitt, M.D.

Nicole Cherie Schmitt, M.D.

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Photo of Dr. Nicole Schmitt, M.D.

Assistant Professor of Otolaryngology - Head and Neck Surgery

Female

Languages: English, French

Expertise: Aerodigestive Disorders, Benign Thyroid Disorders, Benign Tumors of the Head and Neck, Carcinoma of the Tongue, Clinical Trials, Head and Neck Cancers, Head and Neck Conditions, Head and Neck Surgery, Head and Neck Tumors, Laryngeal Cancer, Melanoma, Minor Salivary Gland Cancers, Oral Cancers, Oral Cavity Cancers, Otolaryngology (ENT), Parathyroid Diseases, Parathyroid Surgery, Parotid Cancer, Parotid Gland Tumors, Robotic Surgery, Salivary Gland Tumors, Sentinel Lymph Node Biopsy, Sleep Apnea, Sleep Apnea Surgery, Thyroid Cancer, Thyroid Diseases, Thyroid Disorders, Thyroid Masses, Thyroid Surgery, Thyroid Tumors, Tongue Cancer, Tonsil Cancer ...read more

Research Interests: Platinum-based chemotherapy drugs and immunotherapy for head and neck cancer treatment

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Locations

Johns Hopkins Health Care and Surgery Center
Appointment Phone: 301-896-3330

6420 Rockledge Drive
Suite 4920
Bethesda, MD 20817 map

Background

Nicole C. Schmitt, M.D., is a head and neck cancer surgeon with the Johns Hopkins Kimmel Cancer Center in the Washington, D.C. area, as well as an assistant professor of otolaryngology-head and neck surgery for Johns Hopkins University School of Medicine. Dr. Schmitt has been integral in building Johns Hopkins' head and neck oncology multidisciplinary program and multidisciplinary sleep apnea program in the National Capital Region, and is a member and alternate surgical representative for the Suburban Hospital Cancer Committee. She is board certified in head and neck surgery by the American Board of Otolaryngology.

Dr. Schmitt has an expertise in surgical treatment and surveillance of patients with benign and malignant tumors of the head and neck; robotic surgery; benign and malignant thyroid and parathyroid disease; melanoma and non-melanoma skin cancers of the head and neck; squamous cell carcinoma of the upper aerodigestive tract; salivary tumors; and surgery for obstructive sleep apneas. 

Dr. Schmitt earned her medical degree from the Washington University School of Medicine in St. Louis, Missouri. She completed a residency in otolaryngology at the University of Washington in Seattle, Washington, where she also completed a research fellowship that studied toxicities of cisplatin chemotherapy in the mouse inner ear and kidney. Dr. Schmitt continued her studies with a fellowship in head and neck surgical oncology and tumor biology at the University of Pittsburgh, where she went on to serve as a clinical instructor for their Department of Otolaryngology-Head and Neck Surgery. 

Dr. Schmitt is a special volunteer in the Head and Neck Surgery Branch of the National Institute of Deafness and Communication Disorders for the National Institutes of Health (NIDCD/NIH). She is also a member of the Endocrine Committee, Head and Neck Surgery Committee and the Head and Neck Surgery Education Committee for the American Academy of Otolaryngology-Head and Neck Surgery, as well as a member of the Women's Committee and the Research Committee for the American Head and Neck Society. 

Dr. Schmitt is the principal investigator for the Otolaryngology Surgeon Scientist Program for the Head and Neck Surgery Branch of NIDCD/NIH. Her research interests include the use of platinum-based chemotherapy drugs and immunotherapy for the treatment of head and neck cancer. She has contributed to numerous publications, presentations, posters and book chapters. Dr. Schmitt has received research funding from the Johns Hopkins University Department of Otolaryngology, the NIDCD/NIH, the American Hearing Research Foundation and the American Academy of Otolaryngology-Head and Neck Surgery. She is an ad hoc reviewer for Otolaryngology-Head and Neck Surgery, Head and Neck, JAMA Otolaryngology-Head and Neck Surgery, and Oral Oncology, where she also serves as an editorial board member. Dr. Schmitt is also a clinical mentor of otolaryngology for residents from Walter Reed National Military Medical Center. 

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Titles

  • Assistant Professor of Otolaryngology - Head and Neck Surgery

Departments / Divisions

Education

Degrees

  • MD, Washington University School of Medicine in St Louis (2006)

Residencies

  • University of Washington Medical Center / Otolaryngology Head and Neck Surgery (2013)

Fellowships

  • University of Pittsburgh Medical Center / Head and Neck Surgery (2015)

Board Certifications

  • American Board of Otolaryngology - Head and Neck Surgery / Otolaryngology (2014)

Research & Publications

Research Summary

Dr. Schmitt’s research interests include mechanisms and toxicity profiles of platinum-based chemotherapy drugs. Current studies are focused on improving our understanding of the mechanisms by which these drugs kill head and neck cancer cells, as well as ways to combine them with other chemotherapeutic, targeted or immune therapies to improve their efficacy and decrease associated toxicities. Dr. Schmitt has also published on hearing loss associated with platinum-based chemotherapy agents.

Clinical Trials

Dr. Schmitt is the principal investigator for the Otolaryngology Surgeon Scientist Program for the Head and Neck Surgery Branch of NIDCD/NIH. Learn more here

Selected Publications

View all on Pubmed

Schmitt NC, Sharma A, Gilbert MR, Kim S. Early T stage salivary duct carcinoma: Outcomes and implications for patient counseling. Otolaryngol Head Neck Surg, in press.

Schmitt NC, Ferris RL. STAT1 activation is enhanced by cisplatin and variably affected by EGFR inhibition in HNSCC cells. Mol Cancer Ther. 2015 Jul 3. pii: molcanther.0305.2015.

Mitchell RM, Mendez E, Schmitt NC, Bhrany AD, Futran ND. Antibiotic prophylaxis in patients receiving free flap reconstruction. JAMA Otolaryngol 2015; doi:10.1001/jamaoto.2015.0513.

Schmitt NC, Duvvuri U. Transoral robotic surgery for oropharyngeal squamous cell carcinoma. Curr Opin Otolaryngol Head Neck Surg 2015; 23: 127-131.

Trivedi S, Concha-Benavente F, Srivastava RM, Jie HB, Gibson SP, Schmitt NC, Ferris RL. Immune biomarkers of anti-EGFR monoclonal antibody therapy in squamous cell carcinomas of the head and neck. Ann Oncol 2014; 26:40-47.

Activities & Honors

Honors

  • Young Investigator Award, American Head and Neck Society and American Academy of Otolaryngology – Head and Neck Surgery, 2013

Memberships

  • American Head and Neck Society, 2015

    Member

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    • Women's Committee
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    • Research Committee
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  • American Thyroid Association, 2015
  • American Society of Clinical Oncology, 2014
  • American Academy of Otolaryngology-Head and Neck Surgery, 2006

    Member

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    • Endocrine Committee
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    • Head and Neck Surgery Committee
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    • Head and Neck Surgery Education Committee
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Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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