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Rajat Mittal, M.S., Ph.D.

Photo of Dr. Rajat Mittal, M.S., Ph.D.
  • Joint Appointment in Medicine

Research Interests

Computational ?uid dynamics; Hemodynamics; Bio?uid dynamics; Fluid-structure interaction; Biomedical engineering

Background

Dr. Rajat Mittal is a professor of medicine at the Johns Hopkins University School of Medicine and professor of mechanical engineering at the Whiting School of Engineering. His research focuses on developing computational methods to model a variety of physiological flows, with particular focus on cardiovascular, cerebrovascular and cardiac hemodynamics, and phonatory aerodynamics. Dr. Mittal also works as a core faculty member at the Johns Hopkins Institute for Computational Medicine and Institute for Data Intensive Engineering and Science.

Dr. Mittal received his undergraduate degree from the Indian Institute of Technology in Kanpur, India. He earned a master’s degree from the University of Florida and a doctorate in applied mechanics from the University of Illinois Urbana-Champaign. He completed postdoc research in flow mechanics at Stanford University.

Prior to joining Johns Hopkins in 2009, Dr. Mittal was director of the George Washington University Center for Biomimetics and Bioinspired Engineering and a professor at George Washington University.

Dr. Mittal was most recently honored with American Physical Society and American Society of Mechanical Engineers fellowships.

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Titles

  • Joint Appointment in Medicine

Departments / Divisions

Education

Degrees

  • Ph.D., University of Illinois (Urbana-Champaign) (Illinois) (1995)
  • M.S., University of Florida (Florida) (1991)

Additional Training

Postdoctoral Fellow, Center for Turbulence Research, Stanford University / Flow Turbulence (1996)

Research & Publications

Research Summary

Dr. Mittal conducts research in computational modeling of physiological fluid dynamics. He was trained as a fluid dynamicist, and has extensive background in computational fluid dynamics, turbulence, fluid-structure interaction, high-performance computing and biomechanics. For the past fifteen years, he has been developing computational methods to model a variety of physiological flows with particular focus on cardiovascular and cardiac hemodynamics, and phonatory aerodynamics. A hallmark of his research is the development of multiphysics models that couple a variety of physical domains such as fluid flow, solid mechanics, acoustics and biochemistry, in order to provide unique modeling capabilities and insights into the biophysics of organ function in health and disease. Current research focuses on CT based diagnostics for coronary artery disease, biophysics of cardiac auscultation and mechanisms for thrombogenesis, prosthetic heart valves and cerebral aneurysms.

Lab Website: Flow Physics and Computation Lab

Technology Expertise Keywords

Fluid dynamics, hemodynamics, cardiac biomechanics, cardiovascular biomechanics, aneurysms, cardiac prostheses, phonation, speech, biomechanical modeling, speech, acoustics, organ biomechanics, thrombosis.

Selected Publications

Seo, J.H., Bakhshaee, H., Garreau, G., Zhu, C., Andreou, A., Thompson, W.R. and Mittal, R., 2017. A method for the computational modeling of the physics of heart murmurs. Journal of Computational Physics, 336, pp.546-568.

Harfi, Thura T., Jung-hee Seo, Hayder S. Yasir, Nathaniel Welsh, Susan A. Mayer, Theodore P. Abraham, Richard T. George, and Rajat Mittal. The E-wave propagation index (EPI): A novel echocardiographic parameter for prediction of left ventricular thrombus. Derivation from computational fluid dynamic modeling and validation on human subjects. International journal of cardiology 227 (2017): 662-667.

Seo, J.H., Abd, T., George, R.T. and Mittal, R., 2016. A coupled chemo-fluidic computational model for thrombogenesis in infarcted left ventricles. American Journal of Physiology-Heart and Circulatory Physiology, 310(11), pp.H1567-H1582.

Xue, Q., Zheng, X., Mittal, R. and Bielamowicz, S., 2014. Subject-specific computational modeling of human phonation. The Journal of the Acoustical Society of America, 135(3), pp.1445-1456.

Mittal, R., Erath, B.D. and Plesniak, M.W., 2013. Fluid dynamics of human phonation and speech. Annual Review of Fluid Mechanics, 45, pp.437-467.

Activities & Honors

Honors

  • Fellow, American Physical Society, 2011 - 2012
  • Fellow, American Society of Mechanical Engineers, 2011 - 2012
  • Lewis Moody Award from the American Society of Mechanical Engineers, 2006 - 2007
  • Associate Fellow, American Institute of Aeronautics and Astronautics, 2005 - 2006
  • Fellows Lecture, Pratt & Whitney, East Hartford, CT, 1999 - 1999
  • Francois Frenkiel Award, American Physical Society, 1996

Memberships

  • American Society of Mechanical Engineers
  • American Institute of Aeronautics and Astronautics

Videos & Media

Recent News Articles and Media Coverage

Preventing blood clots with a new metric for heart function,  Texas Advanced Computing Center (January 30, 2017)

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