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Seth Martin, M.D., M.H.S.

Seth Shay Martin, M.D., M.H.S.

Photo of Dr. Seth Martin, M.D., M.H.S.

Co-Director, Advanced Lipid Disorders Center

Assistant Professor of Medicine


Expertise: Abdominal Aneurysms, Arterial Occlusive Disease, Atherosclerosis, Atherosclerosis Imaging, Cardiac Disease, Cardiology, Cardiovascular Diseases, Cardiovascular Medicine, Cardiovascular Risk Stratification, Chest Pain, Clinical Cardiology, Clinical Lipidology, Coronary Artery Disease, Dyslipidemia, General Cardiology, Heart Attack, Heart Disease, High Cholesterol, Hypertension, Inherited Heart Diseases, Ischemic Heart Disease, Preventive Cardiology, Risk Factor Modification, Stress Testing, Subclinical Atherosclerosis, Valvular Heart Disease more

Research Interests: Cardiovascular Risk Assessment; Dyslipidemia; Mobile Health Technology; Primary and secondary prevention of coronary heart disease; Individuals with a family history of heart disease; Improved strategies for management of cardiovascular risk factors; Preventive Cardiology more

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The Johns Hopkins Hospital
Appointment Phone: 410-502-0469

600 N. Wolfe Street
Carnegie 591
Baltimore, MD 21287 map
Fax: 410-367-2224


Dr. Seth S. Martin received his Bachelor of Science degree from Washington and Lee University, graduating summa cum laude and Phi Beta Kappa. He went on to receive his medical degree from the University of Pennsylvania and completed his internal medicine training at Duke University.

Dr. Martin then completed a cardiology fellowship at the Johns Hopkins University School of Medicine. He was designated the Henry R. Kravis & Marie-Josée Cardiovascular Fellow and also served as a Pollin Cardiovascular Prevention Fellow. Dr. Martin was awarded the Howard S. Silverman Research Award for originality and creativity in medical research. Additionally, he was recognized as an Up and Coming Future Star of Cardiology by the American College of Cardiology. During his fellowship, Dr. Martin obtained a Master of Health Science degree at the Johns Hopkins Bloomberg School of Public Health.

After completing the fellowship, Dr. Martin joined the Johns Hopkins Cardiology faculty. He is a core faculty member with the Ciccarone Center for the Prevention of Heart Disease and co-directs the Advanced Lipid Disorders Center. Dr. Martin also serves as an Associate Faculty member in the Welch Center for Prevention, Epidemiology, and Clinical Research. He has a longstanding interest in preventive cardiology, in particular cardiovascular risk assessment, lipidology, and mobile health technology.

Dr. Martin cares for patients with both acute and chronic illnesses and serves on the Hopkins Bedside Medicine Faculty. He is a Firm Faculty Clinical Coach and Educator with the Janeway Firm of the Osler Medical Residency. He also participates in teaching medical students and public health students.

Dr. Martin has published more than 150 articles in leading cardiology and medicine journals, as well as 12 book chapters. He contributed to an update to preventive cardiology published in Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. He serves as Associate Editor for the American College of Cardiology’s CardioSource Dyslipidemia Clinical Community and as an Associate Editor for the Journal of Clinical Lipidology. more


  • Co-Director, Advanced Lipid Disorders Center
  • Assistant Professor of Medicine

Departments / Divisions



  • MD, University of Pennsylvania School of Medicine (2008)


  • Duke University School of Medicine / Internal Medicine (2011)


  • Johns Hopkins University School of Medicine / Cardiology (2015)

Board Certifications

  • American Board of Internal Medicine / Internal Medicine (2011)

Research & Publications

Clinical Trials

mActive: A Blinded, Randomized mHealth Activity Trial

Selected Publications

View all on Pubmed

Plante TB, Urrea B, MacFarlane ZT, Blumenthal RS, Miller ER 3rd, Appel LJ, Martin SS. Validation of the Instant Blood Pressure Smartphone App. JAMA Intern Med. 2016 May 1;176(5):700-2. doi: 10.1001/jamainternmed.2016.0157. PubMed PMID: 26938174; PubMed Central PMCID: PMC4922794.

Martin SS, Blaha MJ, Elshazly MB, Toth PP, Kwiterovich PO, Blumenthal RS, Jones SR. Comparison of a novel method vs the Friedewald equation for estimating low-density lipoprotein cholesterol levels from the standard lipid profile. JAMA. 2013 Nov 20;310(19):2061-8. doi: 10.1001/jama.2013.280532. PubMed PMID: 24240933; PubMed Central PMCID: PMC4226221

Martin SS, Blaha MJ, Elshazly MB, Brinton EA, Toth PP, McEvoy JW, Joshi PH, Kulkarni KR, Mize PD, Kwiterovich PO, Defilippis AP, Blumenthal RS, Jones SR. Friedewald-estimated versus directly measured low-density lipoprotein cholesterol and treatment implications. J Am Coll Cardiol. 2013 Aug 20;62(8):732-9. doi:10.1016/j.jacc.2013.01.079. Epub 2013 Mar 21. PubMed PMID: 23524048

Collins R, Reith C, Emberson J, Armitage J, Baigent C, Blackwell L, Blumenthal R, Danesh J, Smith GD, DeMets D, Evans S, Law M, MacMahon S, Martin S, Neal B, Poulter N, Preiss D, Ridker P, Roberts I, Rodgers A, Sandercock P, Schulz K, Sever P, Simes J, Smeeth L, Wald N, Yusuf S, Peto R. Interpretation of the evidence for the efficacy and safety of statin therapy. Lancet. 2016 Nov 19;388(10059):2532-2561. doi: 10.1016/S0140-6736(16)31357-5. Epub 2016 Sep 8. Review. PubMed PMID: 27616593

Martin SS, Blaha MJ, Blankstein R, Agatston A, Rivera JJ, Virani SS, Ouyang P, Jones SR, Blumenthal RS, Budoff MJ, Nasir K. Dyslipidemia, coronary artery calcium, and incident atherosclerotic cardiovascular disease: implications for statin therapy from the multi-ethnic study of atherosclerosis. Circulation. 2014 Jan 7;129(1):77-86. doi: 10.1161/CIRCULATIONAHA.113.003625. Epub 2013 Oct 20. PubMed PMID: 24141324; PubMed Central PMCID: PMC3919521

Activities & Honors


  • Robert M. Califf & Barton F. Haynes House Staff Research Award, Duke University Medical Center
  • Stanley L. Blumenthal, MD Cardiology Research Award, Johns Hopkins University School of Medicine
  • Up and Coming Future Stars of Cardiology, American College of Cardiology
  • Howard S. Silverman Research Award for Originality & Creativity in Medical Research, Johns Hopkins University School of Medicine
  • Steven N. Blair Award for Excellence in Physical Activity Research, AHA Council on Lifestyle and Cardiometabolic Health
  • Anna Huffstutler Stiles Award in recognition of outstanding academic achievement and innovative thesis research, Johns Hopkins Bloomberg School of Public Health


  • American Heart Association
  • American College of Cardiology
  • Johns Hopkins Institute for Data-Intensive Engineering and Science
  • The Thistle Society, Perelman School of Medicine at the University of Pennsylvania
  • The FH Foundation
  • The American Society for Preventive Cardiology

Professional Activities

  • Member, State Advisory Council on Heart Disease and Stroke Prevention, Maryland Department of Health and Mental Hygiene, Baltimore, MD
  • Co-Chair, Young Hearts Board of Directors, American Heart Association, Baltimore, MD
  • Team Leader, American Heart Association Greater Baltimore Heart Walk, Baltimore, MD
  • Member, American Heart Association Advocacy Coordinating Committee, Maryland
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