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Research Interests: Cancer etiology; evolution; risk prediction; early detection. Aging.
Tomasetti C*, Vogelstein B. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 2015, 347(6217):78-81.
Tomasetti C*, Marchionni L, Nowak MA, Parmigiani G, Vogelstein B. Only three driver gene mutations are required for the development of lung and colorectal cancer. Proc Natl Acad Sci USA 2015, 112(1):118-123.
Tomasetti C*, Vogelstein B, Parmigiani G. Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation. Proc Natl Acad Sci USA 2013, 110(6):1999-2004.
Tomasetti C*. On the probability of random genetic mutations for various types of tumor growth. Bulletin of Mathematical Biology 2012, 74(6):1379-1395.
Tomasetti C*, Levy D. Role of symmetric and asymmetric division of stem cells in developing drug resistance. Proc Natl Acad Sci USA 2010, 107(39):16766-16771.
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