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Beth L. Laube, Ph.D.
Professor of Pediatrics
Research Interests: Asthma; Cystic fibrosis; Dysphagia; Diabetes; Pulmonary Medicine
Dr. Beth L. Laube is a professor of pediatrics at the Johns Hopkins University School of Medicine. Her specialty is pulmonary medicine.
Dr. Laube is an aerosol scientist whose research involves in vivo and in vitro quantification of the deposition and removal of particles in healthy and diseased lungs and noses using radiolabeled aerosols and scintigraphic imaging assessments.
She attended Lake Forest College and received her Ph.D. from the Johns Hopkins Bloomberg School of Public Health.
Dr. Laube served as president of the International Society for Aerosols in Medicine from 2003 to 2005. She also served on the advisory committee to the World Health Organization Product Development Group for the Aerosolized Measles Vaccine Project and on the National Academy of Science’s Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents.
She is a member of the American Thoracic Society and is on the editorial board of the Journal of Aerosol Medicine. Dr. Laube is a frequent advisor to pre-doctoral candidates and post-doctoral fellows at the Johns Hopkins University and at the University of Maryland and has published over 40 peer-reviewed articles.
- Professor of Pediatrics
- Joint Appointment in Medicine
- Joint Appointment in Radiology and Radiological Science
Departments / Divisions
Johns Hopkins Bloomberg School of Public Health
Lake Forest College
Lake Forest, IL
Research & Publications
Dr. Laube’s research involves in vivo and in vitro quantification of the deposition and removal of particles in healthy and diseased lungs and noses using radiolabeled aerosols and scintigraphic imaging assessments.
Computer analyses of the scintigraphic images provide improved methods for assessing the efficacy of a variety of inhaled medications that are administered to the lung or nose. This approach is very useful in the development of aerosol therapies for treating asthma and cystic fibrosis and for answering basic physiologic questions about mucociliary clearance, a major lung defense mechanism.
Laube BL, Sharpless G, Vikani AR, Harrand V, Zinreich SJ, Sedberry K, Knaus D, Barry J, Papania M. "Intranasal Deposition of Accuspray™ Aerosol in Anatomically Correct Models of 2-, 5-, and 12-Year-Old Children." J Aerosol Med Pulm Drug Deliv. 2015 Feb 13. [Epub ahead of print]
Laube BL. "The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination." Respir Care. 2005 Sep;50(9):1161-76.
Garvey C, Fahy B, Lareau S, Braman S, Laube B. "Using your metered dose inhaler (MDI)." Am J Respir Crit Care Med. 2014 Oct 15;190(8):P5-6. doi: 10.1164/rccm.1908P5.
Lin WH, Pan CH, Adams RJ, Laube BL, Griffin DE. "Vaccine-induced measles virus-specific T cells do not prevent infection or disease but facilitate subsequent clearance of viral RNA." MBio. 2014 Apr 15;5(2):e01047. doi: 10.1128/mBio.01047-14.
Laube BL, Sharpless G, Benson J, Carson KA, Mogayzel PJ Jr. "Mucus removal is impaired in children with cystic fibrosis who have been infected by Pseudomonas aeruginosa." J Pediatr. 2014 Apr;164(4):839-45. doi: 10.1016/j.jpeds.2013.11.031. Epub 2013 Dec 24.
Activities & Honors
- Bloomberg School of Public Health Faculty Development Award
- American Thoracic Society
- International Society for Aerosols in Medicine
- Chair, Pediatric Protocol Review Committee, Johns Hopkins Institutional Review Board
- Editorial board, Journal of Aerosol Medicine
- Advisory Committee to the World Health Organization Product Development Group for the Aerosolized Measles Vaccine Project, 2003
- National Academy of Science’s Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents, 2005
- President, International Society for Aerosols in Medicine, 2003