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Charles Bradford Holmes, M.D., M.P.H.

Photo of Dr. Charles Bradford Holmes, M.D., M.P.H.
  • Director and CEO, Centre for Infectious Disease Research in Zambia


Infectious Disease

Research Interests

Infectious diseases; HIV; Tuberculosis; Maternal-child health; Childhood vaccines

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The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 443-997-1900
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-1725


Dr. Charles Holmes is an associate professor of medicine at the Johns Hopkins University School of Medicine. His area of clinical expertise is infectious disease. 

Dr. Holmes earned his M.D. from the Wayne State University School of Medicine. He completed his residency and performed a fellowship in infectious diseases at Massachusetts General Hospital. Dr. Holmes subsequently joined the faculty at Harvard Medical School. He then went on to serve in leadership positions in the Office of the U.S. Global AIDS Coordinator (OGAC) for the President’s Emergency Plan for AIDS Relief (PEPFAR) during both the Bush and Obama administrations (2008– 2012), where he was founding director of the Office of Research and Science and later chief medical officer and deputy U.S. global AIDS coordinator. 

He joined the faculty of the School of Medicine’s Division of Infectious Diseases in February 2015.

Dr. Holmes is internationally recognized for his work on strategies to expand access to antiretroviral treatment and PMTCT services and the integration of evolving science into policy, and has served on numerous WHO and other advisory and guidelines committees. 

As director and CEO at the Centre for Infectious Disease Research, he directs an organization serving Zambians with innovative research, training and service delivery programs in HIV, tuberculosis, maternal-child health, childhood vaccines and other areas. His multidisciplinary research group is focused on large-scale strategies to improve information for public health decision-making and the development of more effective and efficient models of health care delivery. more


  • Director and CEO, Centre for Infectious Disease Research in Zambia

Departments / Divisions



  • MD, Wayne State University School Of Medicine (1999)


  • Massachusetts General Hospital / Internal Medicine (2002)


  • Massachusetts General Hospital / Infectious Diseases (2005)

Board Certifications

  • American Board of Internal Medicine / Infectious Disease (2005)

Activities & Honors


  • Infectious Disease Society of America, Center for Global Health Policy, 2013

    Member, Scientific Advisory Board

  • Center for Global Health Policy

    Center for Global Health Policy, an organization of physicians and scientists dedicated to promoting the effective use of U.S. funding for addressing the global HIV/AIDS and TB epidemics

  • Scientific Advisory Board

    Scientific Advisory Board, an international community of science and medical experts

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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