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Lonny Brett Yarmus, D.O.

Photo of Dr. Lonny Brett Yarmus, D.O.
  • Clinical Director, Division of Pulmonary and Critical Care Medicine
  • Associate Professor of Medicine


Interventional Pulmonology, Lung Cancer, Lung Nodules, Pulmonary and Critical Care Medicine

Research Interests

Central airway obstruction; Lung Cancer; Lung Transplant Airway Stenosis; Interventional Pulmonology


The Johns Hopkins Hospital (Main Entrance)

1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-502-2533 | Fax: 410-630-7491

Johns Hopkins Outpatient Center

Appointment Phone: 410-502-2533
601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 410-955-3408


Dr. Yarmus is a specialist in Interventional Pulmonary and serves as the clinical chief for the Division of Pulmonary and Critical Care and the research director of  Interventional Pulmonology at Johns Hopkins. He is an expert in the minimally invasive diagnosis of all forms of lung cancer. His areas of clinical expertise include interventional pulmonology, minimal invasive diagnostics and lung cancer and leads the lung cancer-screening program at Johns Hopkins. He also has extensive experience in the minimally invasive management of malignant airway obstruction, complex airway management and difficulty airways. In addition, he specializes in the diagnosis and management of pleural diseases and symptom relief with minimally invasive procedures such as indwelling pleural catheters and pleurodesis. He is a fellow of the American College of Chest Physicians and the American Thoracic Society. more


  • Clinical Director, Division of Pulmonary and Critical Care Medicine
  • Director, Interventional Pulmonary Research Core
  • Director, Interventional Pulmonary at Johns Hopkins Bayview
  • Associate Professor of Medicine
  • Associate Professor of Oncology

Departments / Divisions

Centers & Institutes



  • DO, University Of New England College of Osteopathic Medicine (2003)


  • Maine Medical Center / Pulmonary and Critical Care Medicine (2006)


  • Johns Hopkins University School of Medicine / Pulmonary Medicine (2009)
  • Maine Medical Center / Pulmonary and Critical Care Medicine (2009)

Research & Publications

Research Summary

Dr. Yarmus' primary research focus in on the minimally invasive diagnosis of lung cancer and treatment of malignant central airway obstruction. One of his areas of interest is the development of minimally invasive devices to optimize lung cancer diagnostics as well as develop novel minimally invasive therapeutics in the lung. Dr. Yarmus is the PI of the first Interventional Pulmonary NIH award, which studied the effects of endobronchial intratumoral chemotherapy for malignant airway obstruction. In addition, he is investigating a novel micro optical coherence imaging technology for assessing COPD severity and treatment effect in asthma patients after bronchial thermoplasty. He is also is leading a study investigating a breath analysis for diagnosing lung cancer. Dr. Yarmus headed the establishment of the Interventional Pulmonary Outcomes Group (IPOG) whose mission is to provide and support multicenter prospective trials in the Interventional Pulmonary space. His goal is to advance the translational science of Interventional Pulmonology in order to develop new strategies to diagnosis, prevent or treat lung cancer and ultimately improve outcomes in lung cancer patients.

Clinical Trial Keywords

Lung Cancer, EBUS, Navigational Bronchoscopy, Cryobiopsy, Airway Obstruction, Lung Transplantation

Clinical Trials

Local Therapy for Malignant Airway Obstruction

Minimally Invasive Diagnostic Testing for Lung Cancer

Navigational Bronchoscopy



Contact for Research Inquiries

Phone: 410-502-2533

Academic Affiliations & Courses

Graduate Program Affiliation


Activities & Honors


  • American College of Chest Physicians, 2006
  • American Thoracic Society, 2006
  • Society for Critical Care Medicine, 2006

Professional Activities

  • Firm Faculty, Janeway Firm, William Osler Medical Service, Johns Hopkins Hospital
  • Interventional Pulmonary Inpatient Service

Videos & Media

Lung Cancer Screening | Q&A

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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