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Heitham Talal Hassoun, M.D.

Photo of Dr. Heitham Talal Hassoun, M.D.

Medical Director, Global Services

Associate Professor of Surgery


Expertise: Angioplasty, Aortic Aneurysms, Carotid Artery Stenosis, Claudication, Extractional Atherectomy, General Vascular Surgery, Non-Invasive Flow Studies (NIFS), Peripheral Arterial Disease (PAD), Peripheral Vascular Disease, Stenting, Vascular Disease , Vascular Surgery more

Research Interests: Sepsis; Innate Immunity; Molecular mechanisms of visceral organ ischemia/reperfusion injury and inflammation

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The Johns Hopkins Hospital (Main Entrance)
Appointment Phone: 410-955-2618

1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map

Johns Hopkins Outpatient Center
Appointment Phone: 410-955-2618

601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 443-287-2312
Fax: 410-614-2079

Johns Hopkins Bayview Medical Center
Appointment Phone: 410-550-0400

4940 Eastern Avenue
Baltimore, MD 21224 map


Dr. Hassoun joined Johns Hopkins Medicine International in 2012 as the medical director for Global Services and an associate professor in the Department of Surgery.

Dr. Hassoun brings with him a wealth of experience in global health care consulting, including business development, critical planning, knowledge transfer, physician governance and interdisciplinary program development. Dr. Hassoun began his academic career as an assistant professor in the Department of Surgery at The Johns Hopkins Hospital, and he was also part of the initial Johns Hopkins Medicine International management team at Tawam Hospital in the United Arab Emirates, serving as chief of surgery and director of vascular interventional therapy.

Dr. Hassoun’s areas of medical expertise include aortic aneurysms, peripheral arterial disease and venous disorders. more


  • Medical Director, Global Services
  • Associate Professor of Surgery

Departments / Divisions

  • Surgery - Vascular Surgery and Endovascular Therapy

Centers & Institutes



  • MD, Baylor College of Medicine (1997)


  • University of Texas Health Science Center at Houston / General Surgery (2004)


  • Northwestern Memorial Hospital / Vascular Surgery (2005)

Board Certifications

  • American Board of Surgery / General Surgery (2005)
  • American Board of Surgery / Vascular Surgery (2006)

Research & Publications

Selected Publications

Heitham T. Hassoun; Bruce C. Kone; David W. Mercer; Frank G. Moody; Norman W. Weisbrodt; Frederick A. Moore. Post-injury multiple organ failure: The role of the gut. Shock. 2001;15(1):1-10.

Hazim J. Safi; Charles C. Miller III; Tam T. T. Huynh; Anthony L. Estrera; Eyal E. Porat; Anders N. Winnerkvist; Bradley S. Allen; Heitham T. Hassoun; Frederick A. Moore; Richard P. Cambria; et al. Distal Aortic Perfusion and Cerebrospinal Fluid Drainage for Thoracoabdominal and Descending Thoracic Aortic Repair: Ten Years of Organ Protection. Annals of Surgery. 2003;238(3):372-381.

Dmitry N. Grigoryev; Manchang Liu; Heitham T. Hassoun; Chris Cheadle; Kathleen C. Barnes; Hamid Rabb. The local and systemic inflammatory transcriptome after acute kidney injury. Journal of the American Society of Nephrology. 2008;19(3):547-558.

Heitham T. Hassoun; Dmitry N. Grigoryev; Mihaela L. Lie; Manchang Liu; Chris Cheadle; Rubin M. Tuder; Hamid Rabb. Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy. American Journal of Physiology - Renal Physiology. 2007;293(1):F30-F40.

Hazim J. Safi; George V. Letsou; Dimitrios C. Iliopoulos; Mahesh H. Subramaniam; Charles C. Miller III; Heitham Hassoun; Panayiotis J. Asimacopoulos; John C. Baldwin. Impact of retrograde cerebral perfusion on ascending aortic and arch aneurysm repair. Annals of Thoracic Surgery. 1997;63(6):1601-1607.

Heitham T. Hassoun; Norman W. Weisbrodt; David W. Mercer; Rosemary A. Kozar; Frank G. Moody; Frederick A. Moore. Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults. Journal of Surgical Research. 2001;97(2):150-154.

Xiang Li; Heitham T. Hassoun; Rachel Santora; Hamid Rabb. Organ crosstalk: The role of the kidney. Current Opinion in Critical Care. 2009;15(6):481-487.

Heitham T. Hassoun; Lei Zou; Frederick A. Moore; Rosemary A. Kozar; Norman W. Weisbrodt; Bruce C. Kone. α-melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury. American Journal of Physiology - Gastrointestinal and Liver Physiology. 2002;282(6 45-6):G1059-G1068.

Heitham T Hassoun; Rosemary A Kozar; Bruce C Kone; Hazim J Safi; Frederick A Moore. Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric ischemia/reperfusion. Surgery. 2002;132(2):369-376.

Hassoun HT, Matsumura JS: The Cook TX@ thoracic stent graft; Preliminary experience and trial design. Semin in Vascular Surgery 19, 32-39, 2006.

Hassoun HT, Chiou AC, Biggs KL, Matsumura JS: Endovascular graft for thoracic aortic aneurysms. Chapter in Trends in Vascular Surgery 2005, WH Pearce, JS Matsumura, JST Yao, eds., Greenwood Academic, 2005.

"Aortic neck morphology after endovascular repair of descending thoracic aneurysms." Society for Vascular Surgery, 2005.

Kibbe MR, Hassoun HT: 16 Acute mesenteric ischemia. 5 Vascular system. Chapter in ACS Surgery: Principles & Practice, Souba WW, Fink MP, Jurkovich GJ, et al, Eds. WebMD Inc., 2005.

Hassoun HT, Miller CC, Huynh TT, Estrera AL, Smith JJ, Safi HJ: Cold visceral perfusion improves early survival in patients with acute renal failure after thoraco-abdominal aortic aneurysm repair. J Vasc Surg. 39:506-512, 2004.

Hassoun HT, Moore FA: The role of gut hypoperfusion in multiple organ failure. Chapter in Current Techniques in Modern Vascular Surgery, JST Yao, WH Pearce, eds., McGraw-Hill Publishers, 2000, pp. 419-430.

Activities & Honors


  • Lifeline Clinician Scientist Career Development Award, National Heart Lung and Blood Institute and American Vascular Association
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