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Murray Ramanathan, Jr, M.D.
Murugappan Ramanathan, Jr, M.D.
4.8 out of 5
Medical Director, Johns Hopkins Otolaryngology-Head and Neck Surgery- National Capital Region
Associate Professor of Otolaryngology - Head and Neck Surgery
Specializes in: Adults (18+ years)
Languages: English, Tamil
Expertise: Cerebrospinal Fluid (CSF) Leaks, Chronic Sinusitis with Polyps, Complex Skull Reconstruction, Endoscopic Frontal Sinus Surgery, Esthesioneuroblastoma, Nasal Obstruction, Nasal Polyps, Otolaryngology, Paranasal Sinus Tumors, Pituitary Tumors, Revision Endoscopic Sinus Surgery, Revision Frontal Sinus Surgery, Sellar Tumors, Sinonasal Inverting Papillomas, Sinus Problems, Sinusitis, Sinusitis and Nasal Polyposis, Skull Base Tumors, Suprasellar Tumors ...read more
Research Interests: Molecular and immunologic (innate and adaptive) mechanisms underlying the pathogenesis of chronic rhinosinusitis with nasal polyps; Role of Allergy and Environmental pollutants in propagating sinonasal inflammation ...read more
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Johns Hopkins Health Care and Surgery Center
APPOINTMENT PHONE: 301-896-3330
6420 Rockledge Drive Suite 4920 Bethesda, MD 20817
Dr. Ramanathan was born and raised in Dallas, TX, and received a bachelor's degree in Molecular Biophysics and Biochemistry from Yale University. He subsequently received his M.D. from The University of Texas Medical Branch at Galveston where he graduated with highest honors and completed his internship in general surgery and residency in otolaryngology-head and neck surgery at Johns Hopkins. Upon completion of his residency, he received additional fellowship training in advanced endoscopic sinus and minimally invasive skull base surgery at Johns Hopkins.
Dr. Ramanathan evaluates patients primarily at the Johns Hopkins Healthcare and Surgery Center in Bethesda, Maryland, as a part of the greater Washington D.C. region practice of Johns Hopkins Otolaryngology-Head and Neck Surgery. If indicated, he can also perform surgery at Suburban Hospital in Bethesda or at Johns Hopkins Hospital in Baltimore.
He maintains a very busy clinical practice primarily focused on complex revision endoscopic sinus surgery, endoscopic approaches to the orbit, and the endoscopic management of sinonasal and skull base tumors including inverted papilloma and esthesioneuroblastoma. Dr. Ramanathan is also the consultant rhinologist/skull base surgeon for complicated sinusitis and sinonasal/skull base tumor patients at the Warren Grant Magnuson Clinical Center at the National Institutes of Health in Bethesda
As a surgeon-scientist, Dr. Ramanathan also directs an National Institutes of Health funded laboratory to study the role of air pollution in causing chronic rhinosinusitis. He is the recipient of numerous prestigious research awards and grants. He has published over 65 peer reviewed articles, reviews, and book chapters and is frequently invited to speak about his research at national and international meetings.
- Medical Director, Johns Hopkins Otolaryngology-Head and Neck Surgery- National Capital Region
- Chief, Otolaryngology, Suburban Hospital/Johns Hopkins Medicine
- Associate Professor of Otolaryngology - Head and Neck Surgery
- Associate Professor of Neurosurgery
Departments / Divisions
- MD, University of Texas Medical Branch School of Medicine (2004)
- Johns Hopkins University School of Medicine / Otolaryngology (2009)
- American Board of Otolaryngology - Head and Neck Surgery / Otolaryngology (2010)
Research & Publications
Selected PublicationsView all on Pubmed
Mendiola M, Tharakan A, Chen M, Asempa T, Lane AP, Ramanathan M Jr. Characterization of a High Dose Ovalbumin Model of Allergic Sinonasal Inflammation. International Forum of Allergy and Rhinology, 2016 Apr 5. doi: 10.1002/alr.21768
Tharakan A, Halderman A, Lane AP, Biswal S, Ramanathan M Jr.Reversal of Cigarette Smoke Extract Induced Sinonasal Epithelial Cell Barrier Dysfunction Through Nrf2 Activation. International Forum of Allergy and Rhinology, 2016 Aug 31. doi: 10.1002/alr.21827
London NR, Tharakan A, Rule A, Lane AP, Biswal S, and Ramanathan M Jr. Air pollutant mediated disruption of sinonasal epithelial cell barrier function is reversed by activation of the Nrf2 pathway. Journal of Allergy and Clinical Immunology (2016), doi: 10.1016/j.jaci.2016.06.027
London NR, Tharakan A, Lane AP, Biswal S, Ramanathan M Jr. Nrf2 activation restores house dust mite induced sinonasal epithelial cell barrier dysfunction, International Forum of Allergy and Rhinology, 2017 May;7(5):536-541. doi: 10.1002/alr.21916
Ramanathan M Jr., London, NR Jr., Tharakan A, Surya, N., Sussan, TE, Rao, X, Lin, SY, Toskala E, Rajagopalan S, Biswal, S. Airborne particulate matter induces non-allergic eosinophilic sinonasal inflammation in mice. Am J Respir Cell Mol Biol. 2017 Feb 28. doi: 10.1165/rcmb.2016-0351OC
London NR Jr, Tharakan A, Mendiola M, Sussan TE, Chen M, Dobzanski A, Lane AP, Sidhaye V, Biswal S, Ramanathan M Jr. Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis. Int Forum Allergy Rhinol. 2018 Oct 3. doi: 10.1002/alr.22222. PMID: 30281933
Activities & Honors
- Prince Edmund Fowler Award for Outstanding Basic Science Thesis, Triological Society
- Johns Hopkins Clinician Scientist Award
- American Rhinologic Society Basic Science Research Award
Videos & Media
Sinus Surgery Myths | Murray Ramanathan, M.D.”
Recent News Articles and Media Coverage
Treatment Options for Sinus Relief Webinar
Air Pollution May Directly Cause Those Year-Round Runny Noses, According to a Mouse Study Johns Hopkins Press Release April 18, 2017
Sinonasal Inverted Papilloma Masquerading As Nasal Polyps Johns Hopkins Clinical Connection video