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School of Medicine
Aaron Michael Milstone, M.D., M.H.S.
Associate Hospital Epidemiologist, Johns Hopkins Hospital
Associate Professor of Pediatrics
Expertise: Pediatric Infectious Disease
Research Interests: Prevention of hospital-acquired infections; Epidemiology of multi-drug-resistant bacteria in hospitalized children; Diagnosis and transmission of respiratory viruses in hospitalized children; Methicillin-resistant staphylococcus aureus; Hospital epidemiology; Respiratory infections in children; Epidemiology of multidrug-resistant bacteria in hospitalized children ...read more
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Johns Hopkins Pediatrics
Appointment Phone: 410-614-0732
200 N. Wolfe Street
Rubenstein Child Health Building
Baltimore, MD 21287 map
Dr. Aaron M. Milstone is an associate professor of pediatrics at the Johns Hopkins University School of Medicine. He holds a joint appointment in epidemiology at the Bloomberg School of Public Health.
A pediatric epidemiologist, Dr. Milstone specializes in treating infectious diseases in children. He serves as an associate hospital epidemiologist at The Johns Hopkins Hospital and is a member of the Armstrong Institute for Patient Safety and Quality.
Dr. Milstone earned his medical degree from Yale University School of Medicine. He completed both a pediatrics residency and a research fellowship in pediatric infectious diseases at Children's Hospital of Philadelphia. He also completed a pediatric infectious diseases fellowship at Johns Hopkins. He holds a M.H.S. (Graduate Training Program in Clinical Investigation) from the Johns Hopkins Bloomberg School of Public Health and Johns Hopkins University School of Medicine. Dr. Milstone joined the Johns Hopkins faculty in 2007.
His research interests focus on the prevention of hospital-acquired infections in children, respiratory viruses and bloodstream infections in children, and the epidemiology of multidrug-resistant bacteria in hospitalized children.
Dr. Milstone is a fellow of the American Academy of Pediatrics, the Infectious Diseases Society of America, and the Society for Healthcare Epidemiology of America. His many other professional honors include the Pediatric Infectious Diseases Society’s 2014 Young Investigator Award and the inaugural 2013 Caroline B. Hall Clinical Innovation Award.
- Associate Hospital Epidemiologist, Johns Hopkins Hospital
- Associate Professor of Pediatrics
Centers & Institutes
- MD, Yale School of Medicine (2000)
- The Children's Hospital of Philadelphia / Pediatric Infectious Diseases (2003)
- Johns Hopkins University School of Medicine / Pediatric Infectious Diseases (2007)
- American Board of Pediatrics / Pediatric Infectious Diseases (2007)
- American Board of Pediatrics / Pediatrics (2003)
Research & Publications
Dr. Milstone’s research focuses on the prevention of hospital- acquired infections (HAIs) and the emergence of antibiotic resistance in children.
His work is helping to define the prevalence and transmission of multi-drug-resistant bacteria in hospitalized children and to identify interventions to reduce their spread and prevent HAIs.
Dr. Milstone is investigating topics that include:
- Interventions to reduce the spread of multi-drug-resistant bacteria and prevent HAIs in hospitalized children
- Safety and efficacy of chlorhexidine antisepsis in preventing HAIs in children
- Epidemiology and prevention of central line-associated bloodstream infections
- Whether rapid diagnostic tests can enable early access to therapy and reduce transmission of respiratory viruses among hospitalized children
Some of Dr. Milstone’s recent work has focused on understanding the mechanisms of bacterial drug-resistance and on developing strategies to prevent hospital-acquired infections among critically ill children. His research findings have fueled innovative risk-reduction protocols—including the use of daily antiseptic baths to reduce the risk of bloodstream infections in critically ill children—and led to their widespread practice in pediatric hospitals across the U.S.
- Treating Parents to Reduce NICU Transmission of Staphylococcus Aureus Trial (TREAT PARENTS)
- Community Central Line Infection Prevention Trial (CCLIP)
Selected PublicationsView all on Pubmed
Milstone AM, Reich NG, Advani S, Yuan G, Bryant K, Coffin SE, Huskins WC, Livingston R, Saiman L, Smith RB, Song X. "Catheter Dwell Time and CLABSIs in Neonates with PICCs: A Multicenter Cohort Study." Pediatrics 2013 Dec;132(6):e1609-15. Epub 2013 Nov 11
Popoola VO, Carroll KC, Ross T, Reich NG, Perl TM, Milstone AM. "Impact of Colonization Pressure and Strain Type on MRSA Transmission in Children." Clin Infect Dis 2013 Nov;57(10):1458-60. Epub 2013 Aug 13.
Jumani K, Advani S, Gosey L, Reich NG, Milstone AM. "Risk Factors for Peripherally Inserted Central Venous Catheter Complications in Children." JAMA Pediatr. 2013 May 1;167(5):429-35. Epub 2013 Mar 18
Milstone AM, Elward A, Song X, Zerr DM, Orscheln R, Speck K, Obeng D, Reich NG, Coffin SE, Perl TM. "Daily Chlorhexidine Bathing to Reduce Bacteraemia in Critically Ill Children: a Multicentre, Cluster-Randomised, Crossover Trial." Lancet. 2013 Mar 30;381(9872):1099-106. Epub 2013 Jan 28.
Milstone AM, Goldner BW, Ross R, Shepard JW, Carroll KC, Perl TM. "Methicillin- Resistant Staphylococcus aureus Colonization and Risk of Subsequent Infection in Critically Ill Children: Importance of Prevention Nosocomial Transmission." Clin Infect Dis. 2011 Nov;53(9):853-9. Epub 2011 Aug 29.
Academic Affiliations & Courses
Courses and Syllabi
Activities & Honors
- Young Investigator Award, Pediatric Infectious Diseases Society, 2014
- Fellow, Infectious Diseases Society of America, 2014
- Top Doctors (Infectious Diseases), Baltimore magazine, 2012 - 2014
- Fellow, Society for Healthcare Epidemiology of America, 2013
- Election to Society for Pediatric Research, 2013
- Inaugural Caroline B. Hall Clinical Innovation Award, Pediatric Infectious Diseases Society, 2013
- Excellence in Teaching Award, Johns Hopkins Bloomberg School of Public Health, 2011
- Pediatric Investigator Award, Society for Healthcare Epidemiology of America, 2010
- Clinical Research Scholars Award, Johns Hopkins Medicine, 2007 - 2009
- Pediatric Infectious Diseases Society Award recognizing outstanding poster presentation at IDSA National Meeting, 2007
- Fellowship Award, National Pediatric Infectious Disease Society, 2005 - 2007
- Fellow, American Academy of Pediatrics, 2005
- Pediatric Infectious Diseases Society Award recognizing outstanding poster presentation at IDSA National Meeting, 2005
- Election to Alpha Omega Alpha, 2000
- William U. Gardner Prize, “Outstanding medical thesis”, Yale University School of Medicine, 2000
- Medical Student Research Award, Society for Pediatric Research, 2000
- American Academy of Pediatrics
- Infectious Diseases Society of America
- Pediatric Infectious Diseases Society
- Society for Healthcare Epidemiology of America
Videos & Media
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