Dr. Stevens’ vision is to apply Precision Medicine for the benefit of acutely and critically ill patients. His research seeks to identify signatures associated with trauma, surgery, and acute conditions such as stroke, cardiac arrest, and sepsis. To achieve this, he engages with an interdisciplinary team of basic and systems neuroscientists, biomedical and computer engineers, biostatisticians, data scientists, and neuroradiologists. One area of Dr. Stevens' research examines MRI features of the brain connectome to enhance classification and prediction in patients recovering from severe brain injury. Other projects use artificial intelligence methods to analyze features captured through physiologic monitoring, EEG, genomics, and wearable sensors. The overarching aim is to decode phenotypes and increase the accuracy of classification, prediction, and therapy in acutely ill patients. For more details visit our lab website https://lcicm.jhmi.edu/
Lab Website: Laboratory of Computational Intensive Care Medicine
Technology Expertise Keywords
Precision Heath; Data Science; Machine Learning; Brain Mapping
Clinical Trial Keywords
Precision Medicine, Data Science, Artificial Intelligence
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Robba C, Poole D, McNett M, Asehnoune K, Bösel J, Bruder N, Chieregato A, Cinotti R, Duranteau J, Einav S, Ercole A, Ferguson N, Guerin C, Siempos II, Kurtz P, Juffermans NP, Mancebo J, Mascia L, McCredie V, Nin N, Oddo M, Pelosi P, Rabinstein AA, Neto AS, Seder DB, Skrifvars MB, Suarez JI, Taccone FS, van der Jagt M, Citerio G, Stevens RD. Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus. Intensive Care Med. 2020 Dec;46(12):2397-2410. doi: 10.1007/s00134-020-06283-0. Epub 2020 Nov 11. PMID: 33175276
Hannawi Y, Muschelli J, Mulder M, Sharrock M, Storm C, Leithner C, Crainiceanu CM, Stevens RD. Postcardiac arrest neurological prognostication with quantitative regional cerebral densitometry. Resuscitation. 2020 Sep;154:101-109. doi: 10.1016/j.resuscitation.2020.06.023. Epub 2020 Jul 3. PMID: 32629092
Sair HI, Hannawi Y, Li S, Kornbluth J, Demertzi A, Di Perri C, Chabanne R, Jean B, Benali H, Perlbarg V, Pekar J, Luyt CE, Galanaud D, Velly L, Puybasset L, Laureys S, Caffo B, Stevens RD; Neuroimaging for Coma Emergence and Recovery (NICER) Consortium. Early Functional Connectome Integrity and 1-Year Recovery in Comatose Survivors of Cardiac Arrest. Radiology. 2018 Apr;287(1):247-255. doi: 10.1148/radiol.2017162161. Epub 2017 Oct 18. PMID: 29043908
Salluh JI, Wang H, Schneider EB, Nagaraja N, Yenokyan G, Damluji A, Serafim RB, Stevens RD. Outcome of delirium in critically ill patients: systematic review and meta-analysis. BMJ. 2015 Jun 3;350:h2538. doi: 10.1136/bmj.h2538. PMID: 26041151 Free PMC article. Review.
Hannawi Y, Lindquist MA, Caffo BS, Sair HI, Stevens RD. Resting brain activity in disorders of consciousness: a systematic review and meta-analysis. Neurology. 2015 Mar 24;84(12):1272-80. doi: 10.1212/WNL.0000000000001404. Epub 2015 Feb 20. PMID: 25713001 Free PMC article. Review.