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Deborah Persaud, M.D.
Director, Infectious Disease Fellowship Program
Professor of Pediatrics
Expertise: General Pediatrics, Infectious Diseases, Pediatric Infectious Disease
Research Interests: HIV/AIDS drug development; HIV in children; HIV persistence; Mother-to-child HIV transmission
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Johns Hopkins Pediatrics
APPOINTMENT PHONE: 410-614-0732
200 N. Wolfe Street Rubenstein Child Health Building Baltimore, MD 21287
Dr. Deborah Persaud is a professor of pediatrics at the Johns Hopkins University School of Medicine. She holds joint appointments in international health and molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health.
A clinician and researcher specializing in the study and treatment of HIV-1 infection in children, she directs the pediatric infectious diseases fellowship program at the Johns Hopkins Children’s Center.
Dr. Persaud received her B.S. in chemistry from York College in New York. A 1985 graduate of the New York University School of Medicine, she trained in pediatrics at Babies Hospital/Columbia Presbyterian Medical Center in New York, where she was chief resident. She was an infectious disease fellow, an Aaron Diamond postdoctoral research fellow and a faculty member at New York University. She joined the Johns Hopkins faculty in 1997, following a visiting lectureship at the Moi University in Eldoret, Kenya.
Her research interests include HIV/AIDS drug development and mother-to-child HIV transmission.
Dr. Persaud is the scientific chair of the HIV CURE Scientific Committee of the International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) group. She was awarded the prestigious Elizabeth Glaser Scientist Award for her HIV research and was recognized by Nature magazine in 2013 as one of “Ten People Who Mattered This Year.” She was recognized by Time magazine as among the “100 Most Influential People of 2013” for her pediatric HIV treatment research.
- Director, Infectious Disease Fellowship Program
- Professor of Pediatrics
- MD; Medicine, New York University School of Medicine (1985)
- Columbia Presbyterian Medical Center / Pediatrics (1989)
- New York University Medical Center / Pediatric Infectious Diseases (1992)
- New York University Medical Center (1995)
Research & Publications
Dr. Persaud’s research focuses on the mechanisms of HIV persistence in reservoirs in children. She studies the selection and transmission of drug-resistant HIV during chemoprophylaxis for prevention of mother-to-child transmission and their implications for antiretroviral therapy. She also focuses on therapeutic HIV vaccines and the development of field-friendly assays for infant diagnosis and drug-resistance testing.
Luzuriaga K, Gay H, Ziemniak C, Sanborn KB, Somasundaran M, Rainwater-Lovett K, Mellors JW, Rosenbloom D, Persaud D. "Viremic relapse after HIV-1 remission in a perinatally infected child." N Engl J Med. 2015 Feb 19;372(8):786-8. doi: 10.1056/NEJMc1413931.
Rainwater-Lovett K, Luzuriaga K, Persaud D. "Very early combination antiretroviral therapy in infants: prospects for cure." Curr Opin HIV AIDS. 2015 Jan;10(1):4-11
Persaud D, Patel K, Karalius B, Rainwater-Lovett K, Ziemniak C, Ellis A, Chen YH, Richman D, Siberry GK, Van Dyke RB, Burchett S, Seage GR 3rd, Luzuriaga K; Pediatric HIV/AIDS Cohort Study. "Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents." JAMA Pediatr. 2014 Dec;168(12):1138-46. doi: 10.1001/jamapediatrics.2014.1560. Erratum in: JAMA Pediatr. 2015 Jan;169(1):96
Shah SK, Persaud D, Wendler DS, Taylor HA, Gay H, Kruger M, Grady C. "Research on very early ART in neonates at risk of HIV infection." Lancet Infect Dis. 2014 Sep;14(9):797. doi: 10.1016/S1473-3099(14)70893-X.
Clarke DF, Acosta EP, Rizk ML, Bryson YJ, Spector SA, Mofenson LM, Handelsman E, Teppler H, Welebob C, Persaud D, Cababasay MP, Wang J, Mirochnick M; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1097 Study Team. "Raltegravir pharmacokinetics in neonates following maternal dosing." J Acquir Immune Defic Syndr. 2014 Nov 1;67(3):310-5.
Activities & Honors
- 100 Most Influential People, Time, 2013
- Ten People Who Mattered This Year, Nature, 2013
- Elizabeth Glaser Scientist Award, 2005
- Infectious Diseases Society of America
- Pediatric Infectious Diseases Society
- Society for Pediatric Research
- American Society of Microbiology
- Scientific Chair, International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group
- Committee Member, Pediatric AIDS Clinical Trials Group, 2001
- Scientific Chair, HIV CURE Scientific Committee, International Maternal, Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group
- Immunology Subcommittee, Pediatric AIDS Clinical Trials Group, 2001
- Vaccine Subcommittee, Pediatric AIDS Clinical Trials Group, 2001
- Virology Core Committee, Pediatric AIDS Clinical Trials Group, 2000
Videos & Media
Recent News Articles and Media Coverage
“Early Treatment Is Found to Clear H.I.V. in a 2nd Baby,” The New York Times, March 5, 2014