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Chloe Lynne Thio, M.D.

Photo of Dr. Chloe Lynne Thio, M.D.

Professor of Medicine


Expertise: Hepatitis, HIV/AIDS, Infectious Disease

Research Interests: Hepatitis B, hepatitis C, HIV

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The Johns Hopkins Hospital
Appointment Phone: 443-997-1900

600 N. Wolfe Street
Carnegie 346
Baltimore, MD 21287 map
Phone: 410-955-1725


Dr. Chloe Thio is a professor of medicine and an associate professor of molecular microbiology and immunology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include hepatitis, HIV/AIDS and infectious disease. 

Dr. Thio received her B.A. from the University of Pennsylvania. She earned her M.D. from the Yale University School of Medicine. She completed her residency at Hospital of the University of Pennsylvania and performed a fellowship in infectious diseases at Johns Hopkins. 

Her research interests include hepatitis and HIV/AIDS. Her recent research revealed that certain HIV drugs provide added benefit of protecting against hepatitis B. 

Dr. Thio serves on the Research Compensation Subcommittee for the Department of Medicine. She is a member of the American College of Physicians, the American Association for the Study of Liver Disease, the American Society of Clinical Investigation, HIVMA and the Infectious Diseases Society of America. more


  • Professor of Medicine

Departments / Divisions



  • MD, Yale University School of Medicine (1992)


  • Hospital of the University of Pennsylvania - GME / Internal Medicine (1995)


  • Johns Hopkins University School of Medicine / Infectious Diseases (2000)

Board Certifications

  • American Board of Internal Medicine / Infectious Disease (1998)

Research & Publications

Research Summary

Dr. Thio has two primary research interests. The first is HIV-HBV co-infection, where she has projects in Nigeria, Australia and the United States. In addition, she is leading a multicenter international study looking at HIV-HBV co-infection within the ACTG framework.

Her second area is on the human genetic determinants of HBV and HCV clearance, where she examines polymorphisms in human genes in persons that have either recovered from or have a persistent viral hepatitis infection.

Selected Publications

Thio CL, Guo N, Xie C, Nelson KE, Ehrhardt S. "Global elimination of mother-to-child transmission of hepatitis B: Revisiting the current strategy." The Lancet Infectious Diseases. 2015;15(8):981-985.

Ehrhardt S, Xie C, Guo N, Nelson KE, Thio CL. "Breastfeeding while taking lamivudine or tenofovir disoproxil fumarate: A review of the evidence." Clinical Infectious Diseases. 2015;60(2):275-278.

Vergara C, Thio CL, Thomas D, Duggal P. "Polymorphisms in melanoma differentiation-associated gene 5 are not associated with clearance of hepatitis C virus in a European American population." Hepatology. 2015 Jun 23. doi: 10.1002/hep.27954. [Epub ahead of print].

Geller G, Dvoskin R, Thio CL, Duggal P, Lewis MH, Bailey TC, Sutherland A, Salmon DA, Kahn JP. "Genomics and infectious disease: A call to identify the ethical, legal and social implications for public health and clinical practice." Genome Med. 2014 Nov 18;6(11):106. doi: 10.1186/s13073-014-0106-2. eCollection 2014.

Chun HM, Mesner O, Thio CT, Bebu I, Macalino G, Agan BK, Bradley WP, Malia J, Peel SA, Jagodzinski LL, et al.?"HIV outcomes in hepatitis B virus coinfected individuals on HAART." Journal of Acquired Immune Deficiency Syndromes. 2014;66(2):197-205.

Contact for Research Inquiries

855 N Wolfe Street
Room 533
Baltimore, MD 21205 map
Phone: 410-614-6088

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Academic Affiliations & Courses

Graduate Program Affiliation

Molecular Microbiology and Immunology

Activities & Honors


  • American College of Physicians
  • American Society of Clinical Investigation
  • Infectious Diseases Society of America
  • American Association for the Study of Liver Disease

Professional Activities

  • Research Compensation Subcommittee, Johns Hopkins Department of Medicine, 2015

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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