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Edward S Chen, M.D.

Photo of Dr. Edward S Chen, M.D.
  • Assistant Professor of Medicine

Languages: English, Chinese, Mandarin


Emergency Medicine, Pulmonary Medicine, Sarcoidosis

Research Interests

Granulomatous inflammation; Bleomycin induced pulmonary fibrosis; Clinical and translational research in sarcoidosis

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Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-5864
5501 Hopkins Bayview Circle
Asthma and Allergy Center
Baltimore, MD 21224 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-3467
601 N. Caroline St.
Baltimore, MD 21287 map

The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 410-955-2280
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map


Dr. Edward Chen is an assistant professor of medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include emergency medicine, pulmonary medicine and sarcoidosis.

Dr. Chen earned his M.D. from Johns Hopkins. He completed his residency at Columbia Presbyterian Medical Center. He performed a fellowship in pulmonary medicine and a fellowship in pulmonary diseases at Johns Hopkins. 

His research interests include granulomatous inflammation, bleomycin-induced pulmonary fibrosis and clinical and translational research in sarcoidosis. more


  • Assistant Professor of Medicine

Departments / Divisions



  • MD, Johns Hopkins University School of Medicine (1994)


  • New York-Presbyterian/Columbia University Irving Medical Center / Internal Medicine (1997)


  • Johns Hopkins University School of Medicine / Pulmonary Diseases (2002)
  • Johns Hopkins Bayview Medical Center / Pulmonary Medicine (2003)

Board Certifications

  • American Board of Internal Medicine / Critical Care Medicine (2003)
  • American Board of Internal Medicine / Internal Medicine (1997)
  • American Board of Internal Medicine / Pulmonary Disease (2002)

Research & Publications

Selected Publications

View all on Pubmed

Winden TJ, Chen ES, Wang Y, Sarkar IN, Carter EW, Melton GB. "Towards the standardized documentation of e-cigarette use in the electronic health record for population health surveillance and research." AMIA Jt Summits Transl Sci Proc. 2015 Mar 25;2015:199-203. eCollection 2015. PMID: 26306269 Free PMC Article

Oliveira FF, Machado FC, Sampaio G, Marin SM, Chen ES, Smith MC, Bertolucci PH. "Contrasts between patients with Lewy body dementia syndromes and APOE-ε3/ε3 patients with late-onset alzheimer disease dementia." Neurologist. 2015 Aug;20(2):35-41.

Melton GB, Wang Y, Arsoniadis E, Pakhomov SV, Adam TJ, Kwaan MR, Rothenberger DA, Chen ES. "Analyzing operative note structure in development of a section header resource." Stud Health Technol Inform. 2015;216:821-6.

Gigek CO, Chen ES, Smith MA. "Methyl-Cpg-Binding Protein (MBD) family: Epigenomic read-outs functions and roles in tumorigenesis and psychiatric diseases." J Cell Biochem. 2015 Jul 23. doi: 10.1002/jcb.25281. [Epub ahead of print]

Maussion G, Diallo AB, Gigek CO, Chen ES, Crapper L, Théroux JF, Chen GG, Vasuta C, Ernst C. "Investigation of genes important in neurodevelopment disorders in adult human brain." Hum Genet. 2015 Jul 21. [Epub ahead of print]

Pontes TB, Chen ES, Gigek CO, Calcagno DQ, Wisnieski F, Leal MF, Demachki S, Assumpção PP, Artigiani R, Lourenço LG, Burbano RR, Arruda Cardoso Smith M. Reduced mRNA expression levels of MBD2 and MBD3 in gastric carcinogenesis. Tumour Biol. 2013 Dec 13. [Epub ahead of print] PMID: 24338710

Chen ES, Hoch NC, Wang SC, Pellicioli A, Heierhorst J, Tsai MD. Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo. Mol Cell Proteomics. 2013 Dec 3. [Epub ahead of print] PMID: 24302356

Mazzotti DR, Singulane CC, Ota VK, Rodrigues TP, Furuya TK, de Souza FJ, Cordeiro BG, de Oliveira Amaral CM, Chen ES, Jacomini A, de Arruda Cardoso Smith M, Borsatto-Galera B. Association of APOE, GCPII and MMP9 polymorphisms with common diseases and lipid levels in an older adult/elderly cohort. Gene. 2013 Nov 28. pii: S0378-1119(13)01566-7. doi: 10.1016/j.gene.2013.11.040. [Epub ahead of print] PMID: 24291031

Wisnieski F, Calcagno DQ, Leal MF, Dos Santos LC, Gigek Cde O, Chen ES, Pontes TB, Assumpção PP, de Assumpção MB, Demachki S, Burbano RR, Smith Mde A. Reference genes for quantitative RT-PCR data in gastric tissues and cell lines. World J Gastroenterol. 2013 Nov 7;19(41):7121-8. doi: 10.3748/wjg.v19.i41.7121. PMID: 24222956

Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF. Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nat Med. 2013 Dec;19(12):1609-16. doi: 10.1038/nm.3385. Epub 2013 Nov 10. PMID: 24216752

de Oliveira FF, Bertolucci PH, Chen ES, Smith MD. Pharmacological modulation of cognitive and behavioral symptoms in patients with dementia due to Alzheimer's disease. J Neurol Sci. 2013 Oct 14. pii: S0022-510X(13)02961-4. doi: 10.1016/j.jns.2013.10.015. [Epub ahead of print] PMID: 24189208

Tay Z, Koo SH, Nguyen TT, Tan TS, Chen ML, Chin CF, Lim KK, Ang WH, Bay BH, Lee EJ, Chen ES. P-glycoprotein and Vacuolar ATPase Synergistically Confer Anthracycline Resistance to Fission Yeast and Human Cells. Curr Med Chem. 2013;21(2):251-60. PMID: 24059229

Silva PN, Furuya TK, Braga IL, Rasmussen LT, Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payão SL, Mill J, Smith MC. Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. J Alzheimers Dis. 2014;38(1):165-70. doi: 10.3233/JAD-130428. PMID: 23948933

Rice KA, Chen ES, Metcalf Pate KA, Hutchinson EK, Adams RJ. Diagnosis of amyloidosis and differentiation from chronic, idiopathic enterocolitis in rhesus (Macaca mulatta) and pig-tailed (M. nemestrina) macaques. Comp Med. 2013 Jun;63(3):262-71. PMID: 23759529 [PubMed - in process]

Hoch NC, Chen ES, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, Heierhorst J. Molecular basis of the essential s phase function of the rad53 checkpoint kinase. Mol Cell Biol. 2013 Aug;33(16):3202-13. doi: 10.1128/MCB.00474-13. Epub 2013 Jun 10. PMID: 23754745

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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