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Marcia Irene Canto, M.D.
Director of Clinical Research, Division of Gastroenterology
Professor of Medicine
Languages: English, Filipino, Tagalog
Expertise: Barrett's Esophagus, Digestive Disorders, Endoscopic Ultrasound, Endoscopy, Esophageal Cancer, Family History of Cancer, Gastroenterology, Gastroesophageal Reflux Disease (GERD), Gastrointestinal Cancers, Pancreatic and Biliary Disease, Pancreatic Cancer, Pancreatic Cysts ...read more
Research Interests: Familial pancreatic cancer; Barrett's esophagus; Endoscopic mucosal ablation and resection; Cryotherapy; Cryoablation; Endoscopic imaging
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Marcia (Mimi) Canto, M.D., M.H.S. is a Professor of Medicine at The Johns Hopkins University School of Medicine. She is also the Director of Endoscopy at the Johns Hopkins Hospital. Dr. Canto received her Bachelor of Science degree from the University of the Philippines in Manila in 1981 (summa cum laude). She received her Doctor of Medicine degree in 1985 from the University of the Philippines and completed her training in Internal Medicine from State University of New York Sciences Center in Brooklyn, Brooklyn, New York.
Dr. Canto completed a postdoctoral fellowship in Gastroenterology-Hepatology at The Johns Hopkins University School of Medicine and received a Master of Health Science in Clinical Epidemiology from The Johns Hopkins University School of Hygiene and Public Health in 1993. Dr. Canto came back to Johns Hopkins after spending three years at Case Western Reserve University in Cleveland, Ohio for advanced endoscopic training.
Her primary clinical interests include endoscopy, particularly the use of endoscopic ultrasound (EUS) in detecting early pancreatic cancer and its precursors. She has recently shown that endoscopic ultrasound can be used to detect asymptomatic precancerous lesions in patients with a family history of pancreatic cancer.
- Director of Clinical Research, Division of Gastroenterology
- Professor of Medicine
- Professor of Oncology
- MD, University of the Philippines Manila (1985)
- SUNY Downstate Medical Center / Internal Medicine (1990)
- Johns Hopkins University School of Medicine / Gastroenterology (1993)
- University Hospitals Cleveland Medical Center / Gastroenterology (1995)
- University of California at Irvine School of Medicine / Gastroenterology (1995)
- American Board of Internal Medicine / Internal Medicine (1989)
Research & Publications
Clinical Trial KeywordsEndoscopic radiofrequency ablation, Endoscopic cryotherapy, Cancer of the Pancreas Screening, Confocal endomicroscopy Barrett's esophagus
Selected PublicationsView all on Pubmed
Wang, J.S.; Guo, M.; Montgomery, E.A.; Thompson, R.E.; Cosby, H.; Hicks, L.; Wang, S.; Herman, J.G.; Canto, M.I. DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett''s esophagus. Am J Gastroenterol. 2009 Sep;104(9):2153-2160.
Brune, K.A.; Lau, B.; Palmisano, E.; Canto, M.; Goggins, M.G.; Hruban, R.H.; Klein, A.P. Importance of age of onset in pancreatic cancer kindreds. J Natl Cancer Inst. 2010 Jan 20;102(2):119-126.
Harinck, F.; Canto, M.I.; Schulick, R.; Goggins, M.; Poley, J.W.; Fockens, P.; Kluijt, I.; Bruno, M. Surveillance in individuals at high risk of pancreatic cancer: too early to tell? Gut. 2010 Jul;59(7):1005; author reply 1006-1007.
Hector, A.; Montgomery, E.A.; Karikari, C.; Canto, M.; Dunbar, K.B.; Wang, J.S.; Feldmann, G.; Hong, S.M.; Haffner, M.C.; Meeker, A.K.; Holland, S.J.; Yu, J.; Heckrodt, T.J.; Zhang, J.; Ding, P.; Goff, D.; Singh, R.; Roa, J.C.; Marimuthu, A.; Riggins, G.J.; Eshleman, J.R.; Nelkin, B.D.; Pandey, A.; Maitra, A. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer Biol Ther. 2010 Nov 29;10(10):1009-1018.
Hruban, R.H.; Canto, M.I.; Goggins, M.; Schulick, R.; Klein, A.P. Update on familial pancreatic cancer. Adv Surg. 2010;44:293-311.
Lennon, A.M.; Newman, N.; Makary, M.A.; Edil, B.H.; Shin, E.J.; Khashab, M.A.; Hruban, R.H.; Wolfgang, C.L.; Schulick, R.D.; Giday, S.; Canto, M.I. EUS-guided tattooing before laparoscopic distal pancreatic resection (with video). Gastrointest Endosc. 2010 Nov;72(5):1089-1094.
Newman, N.A.; Lennon, A.M.; Edil, B.H.; Gilson, M.M.; Giday, S.A.; Canto, M.I.; Schulick, R.D.; Makary, M.A. Preoperative endoscopic tattooing of pancreatic body and tail lesions decreases operative time for laparoscopic distal pancreatectomy. Surgery. 2010 Aug;148(2):371-377.