Xiaobu Ye is an Assistant Professor of Neurosurgery and Oncology/Biostatistics at the Johns Hopkins School of Medicine (JHMI). She earned her degrees in medicine and an MS in Biostatistics in 1983 and 1994, respectively. She was a faculty member at the Medical University of South Carolina before joining the Division of Oncology Biostatistics at JHMI in 2002.
The main focus of her work has been implementing statistical methods in practical clinical research with an emphasis in clinical trials, relying heavily on scientific rationales in medicine, biology and principles of statistics. Statistical methods include the continual reassessment method (CRM), response surface method, an entropy-based approach, the Bayesian method, and other general statistical approaches to anti-cancer therapeutic development.
Dr. Ye also served as a Senior Statistician for the Center for Complementary and Alternative Medicine and SPORE grants at Johns Hopkins. She is the faculty biostatistician for a research training grant in neuro-oncology mentoring junior investigators in developing basic clinical research skills.
Since 2003, she has been a statistician for the NCI-funded brain tumor clinical trial consortium (ABTC), a collaboration of multiple academic institutions, pharmaceutical companies, and the NCI Cancer Therapy Evaluation Program (CTEP). She is a member of the NCI Brain Malignancies Steering Committee (BMSC) for biostatistics.